What is Olopatadine Hydrochloride?
Olopatadine Hydrochloride has the dual functions of inhibiting histamine release and selectively antagonizing HI receptor, and it has no central nervous system inhibition and cardiac toxic side effects common to HI receptor antagonists. This product can not only inhibit mast cells from releasing histamine, but also antagonize H1 receptor with high selectivity. It has no effect on α-adrenergic receptor, dopamine receptor and M1, M2 receptor, and has few side effects in central nervous system, so it is the first choice for a new generation of antiallergic drugs.
Olopatadine Hydrochloride powder is white or off-white crystalline powder, which has a wide range of pharmaceutical effects.
| Product name | Olopatadine Hydrochloride |
| CAS | 140462-76-6 |
| Molecular formula | C21H24ClNO3 |
| Molecular weight | 373.88 |
| EINECS Number | 604-185-4 |
| Storage condition | Inert atmosphere,Room Temperature |
| Melting point | 242-245°C |
| Solubility | H2O：≥20mg/mL |
| Appearance | White powder |
| Boiling point | 545.7°C at 760 mmHg |
| Merck | 14,6840 |
What is the pharmacological action of Olopatadine Hydrochloride?
Olopatadine Hydrochloride powder is a dibenzoylmethane derivative. The alkaline group in the molecule has a strong antagonistic effect on the receptors and also inhibits the release of inflammatory mediators from mast cells by introducing hydrophilic fusyl acidic groups to overcome the central sedative side effect.
Product Specification
| Item | Specification | Results |
| Appearance | White or off-white solid powder | Complies |
| Identification | By IR | Complies |
| By HPLC | Complies | |
| Melting Point | 95ºC~105ºC | 101ºC~102ºC |
| Loss on Drying | ≤ 1.00% | 0.12% |
| Heavy Metals | ≤ 20ppm | Complies |
| Residue on Ignition | ≤ 0.10% | 0.05% |
| Isomer | ≤ 0.15% | ND |
| Related Substances | Any single impurity: ≤0.50% | 0.45% |
| Total Impurities: ≤1.00% | 0.67% | |
| Purity(HPLC) | ≥ 99.00% | 99.33% |
| Conclusion: | Conform with enterprise specification. |
What are the effects and functions of Olopatadine Hydrochloride powder?
Olopatadine Hydrochloride mainly has anti-allergic effects. First, it has a certain antagonistic effect on histamine receptors. Histamine is a substance related to allergic reactions. Olopatadine Hydrochloride antagonizes the binding of histamine to receptors, thereby blocking the effect of histamine on allergic reactions.
Secondly, Olopatadine Hydrochloride also has a certain inhibitory effect on chemical mediators, such as leukotrienes and other chemicals related to allergies. They can also play a certain inhibitory role, thereby inhibiting the occurrence of allergic reactions.
In addition, it can also be used for skin allergic diseases, as well as eczema or other allergic skin diseases. In short, Olopatadine Hydrochloride powder mainly has anti-allergic effects.
HTML5 atlas of Olopatadine Hydrochloride
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What is the difference between loratadine and Olopatadine hydrochloride?
Olopatadine hydrochloride powder and loratadine powder both have anti-allergic effects and are often used for diseases such as urticaria and allergic rhinitis. However, olopatadine hydrochloride is more suitable for people with strong skin adverse reactions, while loratadine is mainly used for people with obvious respiratory and eye allergic inflammation.
Olopatadine hydrochloride mainly has antihistamine, anti-allergic, and anti-inflammatory effects, and has some relief effects on nasal congestion and runny nose caused by allergic rhinitis. It should be noted that the use of olopatadine hydrochloride may cause drowsiness, and it is recommended to avoid driving or climbing activities after use. Loratadine is mainly used to relieve adverse symptoms of the nose, eyes and other parts caused by allergies. After using loratadine, nasal and eye symptoms can be relieved, but loratadine also has a partial effect on relieving skin itching symptoms.
What are the precautions of Olopatadine Hydrochloride powder?
1. Because the use of Olopatadine Hydrochloride powder will cause drowsiness, users should avoid engaging in dangerous mechanical operations such as driving motor vehicles.
2. People who have been receiving long-term steroid treatment should gradually reduce the amount of steroids under strict management if they need to reduce the amount of steroids due to the use of Olopatadine Hydrochloride.
3. When seasonal patients take Olopatadine Hydrochloride, they should consider starting to use it when the high-incidence season is about to come and continue until the high-incidence season ends.
4. If the use of Olopatadine Hydrochloride is ineffective, be careful not to use it blindly for a long time.
How and where to buy Olopatadine Hydrochloride powder wholesale?
You can trust our order because we have a good record of selling legal educational drugs.
We conduct independent laboratory tests on all products and then sell them to our respected customers.
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Note: This compound should be used for research purposes only. These claims have not been evaluated by the Food and Drug Administration. Please consult your doctor and learn about available studies before using them. This product is not intended to diagnose, treat, cure, or prevent any disease.
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