dilexpal Introduction
Xi'an Faithful BioTech Co., Ltd. is an export-oriented biotechnology and chemical trading company headquartered in Xi'an, Shaanxi Province, China. Founded in 2018, the company focuses on providing pharmaceutical intermediates, plant extracts, food additives, and feed ingredients to the global B2B market.
As a lean, professional supplier, we implement rigorous quality control to ensure batch stability and compliance. With an experienced international sales team, we offer highly competitive prices, reliable delivery times, and one-stop export services.
Our products are widely supplied to the pharmaceutical, health supplement, cosmetic, and feed industries in Europe, North America, Southeast Asia, and the Middle East.
Inositol nicotinate API is metabolized in the body through water dissociation to release Nicotinic acid and Inositol. Therefore, it is often used as a source of Nicotinic acid and is well-known as "non-flushing nicotinic acid". CAS Number: 6556-11-2; Molecular formula: C42H30N6O12; Molecular weight: 810.72; EINECS number: 229-485-9. Clinically, it is mainly used as a vasodilator for peripheral blood vessels. It can also be used as a dietary supplement, functional food additive, and for scientific research purposes.
What are the pharmacological effects of Inositol nicotinate?
Inositol nicotinate API itself is a precursor compound. After entering the body, it will gradually be hydrolyzed under the action of enzymes, slowly releasing two components: Nicotinic acid and Inositol. These two components work together to produce a synergistic effect.
From the perspective of the action logic, the Nicotinic acid generated by hydrolysis can act on the G protein-coupled receptor HCAR2/GPR109A of fat cells, inhibiting fat breakdown, reducing the release of free fatty acids, thereby reducing the generation of TRILAURIN inside the liver and lowering the secretion of very low-density lipoproteins, achieving the effect of regulating lipid levels; Nicotinic acid can also inhibit diacylglycerol acyltransferase 2 (DGAT2), directly interfering with the TRILAURIN synthesis process.
At the microcirculation level, inositol hexa-3-pyridinecarboxylate can specifically dilate blood vessels in damaged or cold-stimulated areas, helping to improve peripheral blood circulation, and also has certain effects of promoting fibrinolysis and assisting in anticoagulation. Thanks to the slow release rate of the released components of the substance, compared with directly ingesting Nicotinic acid, the probability of causing skin redness and other uncomfortable reactions is significantly lower.
What is the function of inositol nicotinate?
Inositol nicotinate has the functions of regulating lipids and improving peripheral circulation. It can help regulate the lipid levels in the body, lower plasma TRILAURIN and low-density lipoprotein cholesterol, and simultaneously increase high-density lipoprotein cholesterol, thereby improving lipid metabolism disorders.
The Inositol nicotinate API can also dilate the blood vessels in the peripheral areas, helping to improve blood circulation. It is suitable for various physical manifestations caused by poor circulation, such as poor blood supply to the extremities, frostbite, and vascular-related head discomfort.
MF of Inositol nicotinate
| CAS | 6556-11-2 |
| Molecular formula | C42H30N6O12 |
| Molecular weight | 810.72 |
| EINECS | 229-485-9 |
| Melting point | 254-256 °C |
| Boiling point | 755.54°C |
| Density | 1.3348 |
Specification
| Item | Specification | Result |
| Appearance | White powder | Complies |
| Identification | HPLC retention time corresponds to thereference standard | Complies |
| Assay | ≥98.0% | 99.20% |
| Loss on drying | ≤1.0% | 0.45% |
| Sulfated Ash | ≤0.1% | 0.03% |
| Heavy metals | ≤ 10ppm | <2 ppm |
| Related Substances(HPLC) | Total impurities ≤1.0% Individual impurity <0.5% |
0.58% 0.21% |
| Microbial Limits | Total Aerobic Count: <1000 CFU/g Yeast & Moulds: <100 CFU/g E.Coli Negative Salmonella Negative |
<100 CFU/g <10 CFU/g Negative Negative |
| Conclusion | Conform with enterprise specification | |
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A variety of shipping methods for you to choose
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS |
Suitable for under 50kg. International door to door express |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order |
|
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Inositol nicotinate API etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.
FAQ:
Q1:Are inositol nicotinate and nicotinic acid the same substance?
No. The latter is in a free form, while the former is a esterification product. Their physical and chemical properties as well as solubility characteristics are all different.
Q2:What research fields does inositol nicotinate mainly apply to?
It is mainly used in biochemical experiments and cell models to conduct research on metabolism and molecular mechanism of action.
Q3:What are the common adverse reactions of it?
The side effects are usually mild, and occasionally there may be mild nausea, sweating, or itching sensations.
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