What is Dequalinium chloride?
Xi'an Faithful BioTech Co., Ltd. is situated in Xi'an, the birthplace of the ancient Silk Road. Leveraging the city's mature logistics network and abundant fine chemical industrial resources, our enterprise has grown into an integrated fine chemical provider that delivers products to global partners. Dequalinium chloride (CAS No. 522-51-0) is a cationic surfactant belonging to the bis-quaternary ammonium salt class. It typically appears as an off-white powder with slight hygroscopicity; its aqueous solution maintains a pH between 5.0 and 7.0. Characterized by mildness and stability, it is suitable for formulation in various mucosal care products. Through its positively charged groups, the substance adheres to the surface structures of microorganisms via electrostatic attraction, disrupting surface permeability barriers and causing the leakage of intracellular metabolites. Simultaneously, it interferes with fundamental metabolic processes and alters internal protein structures, thereby delivering broad-spectrum cleansing and protective effects. It effectively controls various common microorganisms found in the oral cavity and on the body surface, acting rapidly and maintaining efficacy without significant interference from organic matter in the environment.
Application of Dequalinium chloride
It is primarily used for the topical care of body surfaces and mucous membranes. Most commonly found in oral care products such as soothing lozenges and cleansing mouthwashes, it helps maintain oral cleanliness, reduce bad breath, and soothe discomfort in the throat, gums, and oral mucosa. It can also be formulated into gentle washes and soothing creams for superficial skin care and the daily maintenance of intimate mucous membranes; additionally, at low concentrations, it serves as a preservative component in various topical personal care products, helping to extend their shelf life.
COA
| Test Item | Specification | Test Result |
| Appearance | White powder | White powder |
| Odor | Odorless or slight characteristic odor | Odorless |
| Solubility | Soluble in water and ethanol | Complies |
| Assay(C30H40Cl2N4) | 98.0%～102.0% | 99.4% |
| pH(1%aqueous solution) | 5.0～7.0 | 6.2 |
| Loss on Drying | ≤1.0% | 0.38% |
| Residue on Ignition | ≤0.1% | 0.05% |
| Heavy Metals(Pb) | ≤10 ppm | <10 ppm |
| Arsenic(As) | ≤2 ppm | <2 ppm |
| Related Substances Single Impurity | ≤0.2% | 0.08% |
| Total Impurities | ≤0.5% | 0.21% |
| Conclusion | Conform with enterprise specification | |
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Melting point ≥300 °C (lit.)
Molecular formula C30H40Cl2N4
Molecular weight 527.57
Exact mass 526.263000
PSA 59.80000
LogP 1.34060
InChIKey LTNZEXKYNRNOGT-UHFFFAOYSA-N
Mechanism of action of Dequalinium chloride
Electrostatic Adsorption
This substance features a cationic bis-quaternary ammonium structure carrying a positive charge, allowing it to firmly adhere to the negatively charged surface membrane of microorganisms via electrostatic attraction.
Disruption of the Microbial Surface Barrier
Upon adsorption, it disrupts the integrity of the microorganism's outer membrane and alters membrane permeability, compromising the barrier.
Loss of Essential Intracellular Substances
Once the surface barrier is breached, vital intracellular substances-such as electrolytes and proteins necessary for life-leak out, disrupting basic physiological functions.
Inhibition of Microbial Metabolic Activity
The substance penetrates the microorganism, interfering with the normal functioning of internal proteins and enzymes; by blocking microbial proliferation and metabolic cycles, it achieves long-lasting antimicrobial and cleansing effects.
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Our Factory
Package
Shipping Methods
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS |
Suitable for under 50kg. International door to door express |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order |
|
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
FAQ
01. What type of raw material is dequalinium chloride?
Dequalinium chloride is a cationic active powder belonging to the bis-quaternary ammonium salt class; it offers broad-spectrum antimicrobial control capabilities.
02. What are the absorption characteristics of dequalinium chloride?
It acts only on the surface of the skin and mucous membranes and is virtually unabsorbed by mucous membranes, making it relatively mild.
03. What temporary effects may occur from prolonged exposure to high concentrations of dequalinium chloride?
Contact with the oral mucosa may cause a temporary alteration in the sense of taste; this effect resolves on its own once exposure ceases.
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Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.
Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.
Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.
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