Dronedarone Hydrochloride is a white to white hygroscopic powder, and pure dronedarone is a new selective sodium channel blocker, which is the first generation adenosine triphosphate sensitive sodium channel blocker. Clinically, it is used for patients with paroxysmal or persistent atrial fibrillation (AF) or atrial flutter (AFL) to reduce the risk of hospitalization.
| structural formula |
|
|
||
|
Item of analysis |
Standard |
Result of analysis |
||
|
Appearance |
White powder |
Conforms |
||
|
Melting Point |
140°C- 145°C |
141.9°C~142.7°C |
||
|
Identication |
HPLC/UV |
Conforms |
||
|
Heavy Metals |
≤20ppm |
<20ppm |
||
|
Loss on drying |
≤1.0% |
0.07% |
||
|
Related substance |
Total impurities: NMT 1.0% |
0.18% |
||
|
Maximum single impurity: NMT 0.5% |
0.07% |
|||
|
Residue on ignition |
≤0.1% |
0.05% |
||
|
Assay |
≥98.5% |
100.5% |
||
| Conclusion: |
The product conforms to the above specifications.
|
|||
What are the product advantages of dronedarone hydrochloride?
Atrial fibrillation (AF) is a potentially life-threatening disease. Due to the aging population, the incidence and mortality of atrial fibrillation in the world are constantly rising, and it has become a new public health problem. According to statistics, there are 2.5 million patients with atrial fibrillation in the United States and 4.5 million patients in the European Union. At the same time, dronedarone hydrochloride is safer and more effective than amiodarone. Studies have shown that SR33589 can prolong the RR and QT intervals of myocardial cells, and the ventricular APD50 and APD90 are prolonged by 20% and 49% respectively, and the above effects of Dronedarone with the same dose are stronger than amiodarone. In addition, it does not contain iodine, and its lipophilicity is weak. After taking it, phospholipids will not be deposited in the lungs, so there are fewer adverse reactions outside the cardiovascular system than amiodarone. Therefore, after it was approved by the US Food and Drug Administration (FDA) in July 2009, it gradually occupied the whole market, and it was used as the main product in the 2011 American version and the 2010 European version of atrial fibrillation guidelines.
Can dronedarone hydrochloride be taken for a long time?
Multaq powder is of great significance for maintaining the normal rhythm of the heart. In some patients with arrhythmia, such as paroxysmal or persistent atrial fibrillation, taking it regularly for a long time can effectively control symptoms and reduce the risk of cardiovascular events. However, there are great individual differences among patients. For some special people, such as the elderly and those with liver and renal insufficiency, long-term use may cause adverse reactions, such as gastrointestinal discomfort, liver and kidney function damage and so on. For patients with arrhythmia, it is suggested to choose a suitable treatment plan under the guidance of a doctor, and have regular ECG examination to monitor the changes of the condition. At the same time, paying attention to lifestyle adjustment, such as quitting smoking and drinking, and keeping regular work and rest, will help reduce the risk of arrhythmia.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Dronedarone Hydrochloride powder etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.
Disclaimer: The information published on this website comes from the internet, which does not mean that this website agrees with its views or confirms the authenticity of the content. Please pay attention to distinguish it. In addition, the products provided by our company are only used for scientific research. We are not responsible for the consequences of any improper use.
If you are interested in our products, or have critical suggestions on our articles or are not completely satisfied with the products received, please contact us by Email ：sales6@faithfulbio.com . Our team is committed to ensuring the complete satisfaction of customers.
Hot Tags: dronedarone hydrochloride cas 141625-93-6, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China