Ademetionine Disulfate Tosylate CAS 97540-22-2

S-Adenosyl-L-methionine Disulfate Tosylate Introduction

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S-Adenosyl-L-methionine Disulfate Tosylate, abbreviated as SAMe, appears as a white to light yellow solid. Its CAS number is 97540-22-2; its molecular formula is C22H34N6O16S4; its molecular weight is 766.78; and its EINECS number is 249-946-8. Ademetionine disulfate tosylate overcomes the problem of the raw material being prone to inactivation through a special salt formation structure. Most of the products on the market are produced using the biological fermentation process, and the main raw material is extracted and prepared using brewer's yeast. This substance is a very important methyl donor and has a high demand in the dietary nutrition supplement raw material field. It can relieve emotional discomfort, alleviate joint pain caused by osteoarthritis, and also play a role in liver maintenance.
In addition, the pharmaceutical industry and various laboratories also purchase this raw material. The high-purity specification can be used as a control standard for product quality inspection, and can also be used as an experimental reagent to conduct basic research in the direction of cell metabolism and neurological-related diseases.

What is the mechanism of action of SAM-T?

S-Adenosyl-L-methionine Disulfate Tosylate is an important active methyl donor. The molecule carries a transferable methyl group and can participate in a large number of methylation biochemical reactions in the body, providing essential raw materials for the metabolism of phospholipids, neurotransmitters, L-tert-Leucine, and Ribonucleic acid. Through the methylation process, it can assist in the metabolism of emotional-related signaling substances such as serotonin and dopamine, stabilize the levels of brain neurotransmitters, relieve emotional discomfort, and synthesize cell membrane phospholipids to ensure the integrity of nerve cell structure and smooth signal transmission. When acting on joints, it can supplement methyl groups to chondroitin proteoglycans, promote the regeneration and repair of cartilage matrix, increase the lubrication effect of joint synovial fluid, relieve the soreness caused by cartilage friction, and also regulate inflammatory mediators to alleviate mild joint inflammation. For the liver, this substance can help generate Glutathione, enhance the cell's antioxidant capacity, reduce the damage of harmful substances to liver cells, and accelerate fat breakdown and transport to avoid fat accumulation in the liver, repair the liver cell membrane to ensure normal liver metabolism. In laboratory research scenarios, Ademetionine disulfate tosylate can change the gene methylation modification state, intervene in cell proliferation and differentiation, and is often used to conduct basic research in the directions of cell energy metabolism, nerve cell injury, and oxidative stress.

What are the uses of S-Adenosyl-L-methionine Disulfate Tosylate?

The application of S-Adenosyl-L-methionine Disulfate Tosylate mainly falls into two major categories: dietary nutrition supplementation and scientific research quality inspection. As an active methyl supply raw material, it is widely used in the dietary supplement category. It can alleviate mild to moderate depression, improve joint pain and stiffness caused by osteoarthritis, and also protect the liver. At present, relevant experiments have also found that it has potential research value in nerve protection and related tumor fields.
The laboratory and product quality inspection processes also extensively use Ademetionine disulfate tosylate. On the one hand, it can be used as an experimental reagent to explore the basic biochemical mechanisms related to methylation; on the other hand, it can serve as a secondary standard substance for compounds and a certification reference material. During the detection of product content, it can be relied upon to complete qualitative and quantitative detection. The corresponding detection standards can be traced back to authoritative pharmacopoeia institutions such as USP.

MF of S-Adenosyl-L-methionine Disulfate Tosylate

CAS	97540-22-2
Molecular formula	C22H34N6O16S4
Molecular weight	766.78
Melting point	>122°C
EINECS	249-946-8

Specification

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FAQ: 

Q1:What should be kept in mind when using SAM-T?
Consult a doctor before use for therapeutic purposes-especially if you are taking antidepressants or other prescription medications-as potential interactions may occur.
Q2: Are there differences in the regulatory classification of SAMe in different regions?
There are significant differences: many European countries classify it as a prescription-related preparation, whereas in the US market, it is permitted for circulation solely as an ingredient for dietary supplements.
Q3:What are the side effects of S-Adenosyl-L-methionine Disulfate Tosylate?

In the context of daily supplementation, a small number of people may experience mild gastrointestinal discomfort; some individuals might also encounter insomnia, a sensation of slight fullness or pressure in the head, or irritability. These reactions are generally mild and can be alleviated by adjusting the time of intake or reducing the dosage. In very rare cases, sensitive individuals may experience mild skin itching; should persistent discomfort occur, it is recommended to discontinue use and consult a professional.

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