Simvastatin Powder CAS 79902-63-9
Product:Simvastatin powder;Simvastatin;
CAS NO.:79902-63-9
Molecular formula:C25H38O5
Purity & Grade: 99% HPLC; Food grade
MOQ & Package: 100g; Package according to demand
Shipping: Safe and fast delivery
Store & Shelf life: Cool & dry place; 36 months
Lead Time: about 3 days
Warehouse: USA and Germany warehouse
Certificate:COA; HPLC; MSDS; TDS,etc.
Description
What is Simvastatin powder?
Simvastatin powder is a competitive HMG - CoA reductase inhibitor, which is commonly used to reduce the level of low-density lipoprotein cholesterol (LDL - C) and total cholesterol in the blood, and can also slightly increase high-density lipoprotein cholesterol (HDL - C), mainly used for hypercholesterolemia, coronary atherosclerotic heart disease, etc. It itself is an inactive drug precursor that needs to be metabolized into a hydroxy acid form in the liver to exert its effect. It is also commonly used in scientific research experiments. When using it, it is important to wear lab clothes and disposable gloves.
| Product name | Simvastatin powder |
| CAS | 79902-63-9 |
| Molecular formula | C25H38O5 |
| Molecular weight | 418.57 |
| EINECS Number | 616-751-8 |
| melting point | 127-132 °C (lit.) |
| solubility | NA |
| Storage conditions | 2-8°C |
| Appearance | white |
| boiling point | 564.9±50.0 °C |
| Density | 1.11±0.1 g/cm3 |
Product Specification
| Items | Specification | Results |
| Appearance | White powder | Complies |
| Identification | By IR | Complies |
| By HPLC | Complies | |
| Solubility | Dimethyl sulfoxide: ≥ 20mg/mL | Complies |
| Melting Point | 127-132 °C (lit.) | Complies |
| Water Content | ≤ 0.50% | 0.10% |
| Heavy Metals | ≤ 20ppm | Complies |
| Residue on Ignition | ≤ 0.20% | 0.09% |
| Related Substance | Any single impurity: ≤0.10% | 0.06% |
| Total Impurities: ≤1.00% | 0.16% | |
| Assay (on the anhydrous basis) | 98.0%~102.0% | 99.94% |
Conclusion：Conform with enterprise specification .
Where is Simvastatin powder usually used?
- Mainly used for lowering blood lipids and treating cardiovascular diseases：Simvastatin powder is a powerful lipid-lowering drug that competitively inhibits the activity of HMG CoA reductase and reduces endogenous cholesterol production. When used at a dose of 5-80mg, it can reduce low-density lipoprotein (LDL) by up to 50% and is widely used in cardiovascular diseases.
- Has anti-inflammatory and inhibitory effects on extracellular vesicle release：It can reduce the proliferation of PB derived monocytes and synovial cells from rheumatoid arthritis blood stimulated by anti-CD3/anti antibody. Meanwhile, it has the ability to inhibit the release of extracellular vesicles, which may have applications in the treatment of related diseases.
- Applied to research on the treatment of lung diseases：Recent studies have shown that Simvastatin powder plays an active role in the treatment of chronic obstructive pulmonary disease (COPD) and acute respiratory distress syndrome (ARDS), and can reduce the incidence rate and mortality of COPD and ARDS patients.
What are the effects of Simvastatin powder ?
Lowering cholesterol: It is a hydroxymethylglutaryl-CoA reductase inhibitor that can reduce the raw materials for cholesterol synthesis in the liver, thereby achieving the effect of lowering cholesterol. It is commonly used for hypercholesterolemia.
Anti inflammatory: If the blood lipid levels in the body are too high and not improved in a timely manner, it may cause blockage of blood vessels. At this time, using Simvastatin powder has a certain anti-inflammatory effect.
Stable plaque: to a certain extent, it can also play a role in stabilizing plaque, which is commonly used in clinical treatment of coronary atherosclerotic heart disease.
Antitumor: It can significantly inhibit cell proliferation, induce G1 phase blockade of the cell cycle, induce cell apoptosis, and has anti-tumor metastasis effects.
Promote vascular regeneration: It can also activate protein kinase Akt, promote phosphorylation of its substrate eNOS, and promote vascular regeneration.
Simvastatin powder is widely used in the medical field, but it is important to strictly follow medical advice when using it to avoid adverse reactions.
How and where to buy Simvastatin powder wholesale?
Our products undergo experimental testing and are recognized by customers
You can trust our order because we have a good record of selling legal educational drugs.
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
FAQ：
Q1:Can I get samples?
A1: Yes, we can provide you with free samples, but the freight needs to be paid by you, I hope you can understand.
Q2: How to pay?
A2: PI will be sent firstly after our aligned products specification. Payment by T/T, Western Union,Wise Payment,Wechat payment, are ok.
Q3: How is your MOQ?
A3:Normally speaking, our MOQ is 1kg. But we can also accept less quantity such as 100g .
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Note: This compound is only used for laboratory research purposes. The US authorities have not evaluated these claims. Before use, please consult your doctor and learn about available research. This product is not intended for the diagnosis, treatment, cure, or prevention of any disease.
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