99% Vinorelbine Tartrate Powder CAS 125317-39-7
Product Name:Vinorelbine Tartrate
Description
What is Vinorelbine Tartrate?
99% Vinorelbine Tartrate powder is the tartrate form of vinorelbine, a semi-synthetic vinblastine compound, which is a M-phase specific drug with a similar mechanism of action to vincristine. Mainly by selectively blocking tubulin polymerization in mitotic cells to form microtubules, which can induce tubulin depolymerization, hinder spindle microtubules, stop cell division in the middle stage, and affect the synthesis of tubulin in neuronal axons. very little. Due to the poor affinity of NVB for axonal microtubules and its effect on axons only at high concentrations, neurotoxicity is lower than other vinblastine drugs and has a larger therapeutic index. The human pharmacokinetic study of vinorelbine shows that after intravenous administration, it is a three-compartment model, with a large volume of distribution, PPB can reach 50% to 80%, and the plasma clearance rate is high. The terminal clearance phase T1/2 is 40h, the tissue distribution was faster, and the concentration in tissues was significantly higher than that of vincristine (VCR) and vindesine (VDS). The plasma clearance rate is 0.8L/(kg·h), mainly secreted by the biliary tract and excreted with the feces, and urinary excretion accounts for 10% to 15%. Higher efficacy and fewer adverse reactions to the nervous system.
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Vinorelbine Tartrate Benefits
99% Vinorelbine Tartrate powder is mainly used in:
It is commonly used in the treatment of non-small cell lung cancer (NSCLC), breast cancer, ovarian cancer, head and neck phosphorus cancer, and leukemia, and also has a strong inhibitory effect on small cell lung cancer, colon cancer, brain tumor, malignant melanoma, etc.
Application of Vinorelbine Tartrate
A large number of clinical studies have shown that vinorelbine is one of the most effective drugs for the treatment of non-small cell lung cancer and breast cancer, with a single-drug effective rate of 14% to 35% and 30% to 60%, respectively. Combining chemotherapy with DDP in the treatment of NSCLC and doxorubicin in the treatment of breast cancer, the effective rates can be as high as 30% to 50% and 50% to 77%, respectively. It also has a good curative effect on ovarian cancer, malignant lymphoma, head and neck cancer, and esophageal cancer.
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How To Obtain Samples of Vinorelbine Tartrate?
Welcome to send an inquiry to sunny@faithfulbio.com at any time for a free sample if you need the API powder Vinorelbine Tartrate.
The Best Vinorelbine Tartrate Manufacturer And Supplier
Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.
We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.
Why Choose Faithfulbio Vinorelbine Tartrate?
Faithfulbio specialize in Vinorelbine Tartrate for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.
A variety of shipping methods for you to choose
Transportation Time | Shipping method | Cargo weight requirements | Advantage |
3-7 days | DHL,Germany DHL,Germany DPD, | Suitable for under 50kg. | We have warehouses in Germany and California, the USA, |
7-15 days | By Air | Suitable for more than 50kg. | |
15-60 days | By Sea | Suitable for more than 500kg. |
kindly note: Use this compound for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.
Where To Buy Vinorelbine Tartrate?
Just send an email to sunny@faithfulbio.com, or submit your requirement in the bottom form, we are of service at any time!
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