XEN1101 CAS 1009344-33-5
Product:XEN1101;Encukalner(XEN-1101)
CAS NO.:1009344-33-5
Molecular formula:C23H29FN2O
Purity & Grade: 99% HPLC; Food grade
MOQ & Package: 100g; Package according to demand
Shipping: Safe and fast delivery
Store & Shelf life: Cool & dry place; 36 months
Lead Time: about 3 days
Warehouse: USA and Germany warehouse
Certificate:COA; HPLC; MSDS; TDS,etc.
Description
What is XEN1101?
XEN1101 is a novel, small molecule, selective Kv7.2/Kv7.3 potassium channel opener with a long terminal elimination half-life (approximately 10 days) and can be administered orally once daily.
| Product name | XEN1101 |
| CAS | 1009344-33-5 |
| Molecular formula | C23H29FN2O |
| Molecular weight | 368.49 |
| EINECS Number | NA |
| melting point | NA |
| solubility | NA |
| Storage conditions | -20°C |
| Appearance | From off white to gray powder |
| boiling point | 541.8±50.0 °C |
| Density | 1.125±0.06 g/cm3 (20 ºC 760 Torr) |
Product Specification
| Item | Specification | Results |
| Appearance | gray powder | Conforms |
| Chemical purity (HPLC) | ≥99% | 99.74% |
| Assay(HPLC) | ≥98% | 99.60% |
| Z isomers(HPLC) | ≤1.0% | 0.09% |
| Total impurity(HPLC) | ≤1.0% | 0.26% |
| Residue on ignition | ≤1.0% | 0.02% |
| Loss on drying | ≤0.5% | 0.05% |
| Heavy metal | ≤20ppm | Conforms |
| Conclusion | Conform with enterprise specification | |
Where is XEN1101 used?
XEN1101 is being developed for the treatment of various diseases, including:
Focal epileptic seizures: It is being used to treat focal epileptic seizures, which are one of the most common types of seizures in epilepsy patients.
Major Depression: It is also being explored for the treatment of major depression. Showing certain therapeutic potential.
Bipolar disorder: The product is currently undergoing multiple Phase 3 clinical studies targeting indications such as bipolar disorder.
In summary, it has been mainly researched and developed in the treatment of epilepsy and depression, demonstrating certain therapeutic potential. However, it should be noted that it did not significantly outperform placebo in the phase II trial of treating severe depression from a statistical perspective, so its application in the treatment of depression still needs further research and validation.
What are the effects of XEN1101?
The main effects of XEN1101 are:
Reduce the frequency of epileptic seizures: The product treatment group showed a greater reduction in monthly focal seizure frequency compared to baseline, and the effects of each dose were statistically significant.
Respondent ratio: Responders are defined as patients whose monthly frequency of focal epileptic seizures decreases by 50% or more from baseline. The number of responders increased in a dose-dependent manner.
Good tolerance: The study participants had good tolerance to the product and reported similar side effects to other antiepileptic treatments, including dizziness, nausea, and fatigue. Most people felt good and could continue with the regimen.
Stability: Its half-life is relatively long, taking more than a week to decompose, so the levels in the brain remain consistent over time. This stability allows treatment to start at full capacity and helps avoid sharp peaks that exacerbate side effects, as well as allowing for a decrease in seizure recurrence.
How and where to buy XEN1101 wholesale?
Our products undergo experimental testing and are recognized by customers.
You can trust our order because we have a good record of selling legal educational drugs.
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
FAQ：
Q1:How do you ensure product quality?
A1:1. We have a strict quality management system in place. All batches must pass tests and meet our standards before being released into the warehouse.
2. We will recheck and confirm product quality before delivery.
3. If necessary, we can send samples to a third-party testing agency to obtain a testing report.
Q2:How can we place an order?
A2:1. Please inform us of your requirements.
2. We will provide you with suitable product options and quotations based on your needs.
3. We can provide you with a Certificate of Analysis (COA) and relevant test spectra or samples to verify product quality.
4. Once the quality and price details are confirmed, we will issue a Proforma Invoice (PI).
5. Please confirm your order, complete the payment, and send us the payment slip.
6. We will reconfirm the details before shipping and arrange for shipment.
Q3:Do you offer samples?
A3:We can provide samples for most of our products free of charge. Please cover the cost of express shipping.
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Note: This compound is only used for laboratory research purposes. The US authorities have not evaluated these claims. Before use, please consult your doctor and learn about available research. This product is not intended for the diagnosis, treatment, cure, or prevention of any disease.
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