Givinostat Acid CAS 497833-27-9
Product:Givinostat Acid;CS-2025;Gavinostat
CAS NO.: 497833-27-9
Molecular formula:C24H27N3O4
Purity & Grade: 99% HPLC; Food grade
MOQ & Package: 100g; Package according to demand
Shipping: Safe and fast delivery
Store & Shelf life: Cool & dry place; 36 months
Lead Time: about 3 days
Warehouse: USA and Germany warehouse
Certificate:COA; HPLC; MSDS; TDS,etc.
Description
What is Givinostat Acid?
Givinostat Acid is an HDAC inhibitor. Inhibiting HDAC1 and HDAC3 with IC50 values of 198 nM and 157 nM, respectively.
| Product name | Givinostat Acid |
| CAS | 497833-27-9 |
| Molecular formula | C24H27N3O4 |
| Molecular weight | 421.49 |
| EINECS Number | NA |
| melting point | NA |
| solubility | NA |
| Storage conditions | Store at -20°C |
| Appearance | White crystalline powder |
| boiling point | NA |
| Density | 1.259 |
Product Specification
| Item | Specification | Results |
| Purity(On Dried Base,%) | >99% | 99.38% |
| Appearance | white powder | Complies |
| Color | Complies | Complies |
| Odor &Taste | Characteristic | Complies |
| Identification | Positive | Complies |
| Loss on Drying | ≤1.0% | 0.39% |
| Residue on ignition | ≤0.5% | 0.33% |
| Heavy metals (As Pb) | NMT20PPM | Conforms |
| Related substance | Max Single Impurity≤0.5% | 0.14% |
| Conclusion | Conform with enterprise specification | |
Where is Givinostat Acid usually used?
Givinostat Acid is mainly used for:
Anti inflammatory effect: In vitro studies have shown that it can reduce the release of various pro-inflammatory cytokines from human peripheral blood monocytes stimulated by lipopolysaccharides
Anti cancer effect: It has cytotoxicity against multiple myeloma cell lines and acute myeloid leukemia cell lines
Protecting β - cells: In inflammatory conditions, it is beneficial for the survival of β - cells, increases the viability of pancreatic islet cells, enhances insulin secretion, inhibits the release of MIP-1 α and MIP-2, and reduces apoptosis rate.
Treatment of hepatitis and leukemia: In animal models, it significantly reduces liver damage and significantly prolongs lifespan.
Neuroprotective effect: It promotes the recovery of neural behavior, reduces neuronal deterioration, lowers the degree of damage, and induces glial apoptosis.
What are the effects of Givinostat Acid?
Givinostat Acid has the following effects:Commonly used in scientific research, studies have shown that this compound has potential therapeutic value in anti-inflammatory, anticancer, and neuroprotective aspects.
It should be noted that these studies are mainly based on in vitro and animal experiments, and their effectiveness and safety in humans still need further research and verification.
In addition, the hydrochloride salt hydrate of this compound has been used in related research, and its free form may vary.
How and where to buy Givinostat Acid wholesale?
Our products undergo experimental testing and are recognized by customers.
You can trust our order because we have a good record of selling legal educational drugs.
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
FAQ：
Q1:Do you have CoA for this product?
A1:Yes, we have CoA report for each shipment.
Q2:What is the delivery method?
A2:By air express(default) or by sea(optional).
Q3:How can i get the price?
A3:We usually quote within 24 hours after we get your inquiry(Except weekend and holidays). If you are very urgent to get the price, please email us or contact us in other ways so that we can offer you a quote.
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Note: This compound is only used for laboratory research purposes. The US authorities have not evaluated these claims. Before use, please consult your doctor and learn about available research. This product is not intended for the diagnosis, treatment, cure, or prevention of any disease.
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