What is Tubastatin A?
Tubastatin A is an effective and selective HDAC6 inhibitor with an IC50 value of 15 nM. It exhibits over 1000 fold selectivity towards all isoenzymes except HDAC8 and approximately 57 fold selectivity towards HDAC8.
| Product name | Tubastatin A |
| CAS | 1239262-52-2 |
| Molecular formula | C22H22F3N3O4 |
| Molecular weight | 431.4077096 |
| EINECS Number | NA |
| melting point | NA |
| solubility | NA |
| Storage conditions | under inert gas (nitrogen or Argon) at 2-8°C |
| Appearance | Black powder |
| boiling point | NA |
| Density | NA |
Product Specification
| Item | Specification | Results |
| Purity | ≥98% | 99.55% |
| Appearance | Black powder | Complies |
| Loss on Drying | ≤1.0% | 0.39% |
| Residue on ignition | ≤0.5% | 0.21% |
| Heavy metals (As Pb) | NMT10PPM | 2ppm |
| Related substance | Impurity≤0.5% | 0.14% |
| Conclusion | Conform with enterprise specification | |
Where is Tubastatin A usually used?
Tubastatin A are commonly used in the following research fields:
Neuroprotective study: It showed dose-dependent protection against homocysteine (HCA) - induced neuronal cell death starting at 5 μ M and approaching complete protection at 10 μ M.
Immune regulation research: In inflammation and autoimmune mouse models, it can inhibit HDAC6 and promote Tregs inhibitory activity
Cancer research: It acts on cholangiocarcinoma cell lines and can also reduce the growth of cholangiocarcinoma in the body.
Inflammation and arthritis research: It significantly inhibits paw volume and clinical scores as well as IL-6 expression in arthritis mice.
Ovarian research: It has shown potential for application in the preparation of in vitro activators for primordial follicles
Cell biology research: It can increase cell elasticity
What are the effects of Tubastatin A?
Tubastatin A has multiple biological effects, showing significant biological effects in neuroprotection, immune regulation, anti-tumor, anti-inflammatory, memory consolidation enhancement, and increased cell elasticity.
These effects make it an important tool for studying various disease mechanisms and potential treatment strategies.
Tubastatin A has shown significant therapeutic effects in various disease models, but its side effects require further research and observation.
If there is a need for use, it is recommended to follow the guidance of a professional doctor.
How and where to buy Tubastatin A wholesale?
Our products undergo experimental testing and are recognized by customers.
You can trust our order because we have a good record of selling legal educational drugs.
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
FAQ：
Q1:How do you ensure product quality?
A1:1. We have a strict quality management system in place. All batches must pass tests and meet our standards before being released into the warehouse.
2. We will recheck and confirm product quality before delivery.
3. If necessary, we can send samples to a third-party testing agency to obtain a testing report.
Q2:Do you offer samples?
A2:We can provide samples for most of our products free of charge. Please cover the cost of express shipping.
Q3:What is your lead time for a new order?
A3:For most products in stock, the delivery time is 1-5 business days after payment receipt. For customized products, please discuss further.
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Note: This compound is only used for laboratory research purposes. The US authorities have not evaluated these claims. Before use, please consult your doctor and learn about available research. This product is not intended for the diagnosis, treatment, cure, or prevention of any disease.
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