Tetracycline Hcl Powder CAS 64-75-5

Tetracycline HCl powder is a yellow crystalline powder with molecular formula: C22H25ClN2O8, molecular weight: 480.9, melting point: 220-223 C (lit.), pH (10g/L, 25 C): 1.8-3.0, and no odor. Bitter. Easy to absorb moisture. The color changes gradually in light. Soluble in water and methanol. Ethanol is insoluble in ether and hydroxyl. It is an antibacterial substance isolated from the culture solution of the actinomycetes Streptomyces aureus, an actinomycete. It has a good inhibitory effect on Gram-positive bacteria, Gram-negative bacteria, rickettsia, viral viruses, spirochetes, and even protozoa, but it has no effect on tuberculosis and Proteus.

What is Tetracycline HCl?

Tetracycline HCl powder is the first generation of tetracycline antibiotics, which has broad-spectrum antibacterial characteristics and bactericidal effect at high concentrations and can resist many microorganisms such as Gram-negative and Gram-positive bacteria, chlamydia, mycoplasma, and protozoan parasites. In addition, people who are sensitive to many penicillins can use tetracycline antibiotics as substitutes to treat some diseases. Because of its low cost, it is widely used in the treatment of human and animal infections.

What is the function of Tetracycline HCl?

Tetracycline HCl powder has certain antibacterial activity against Neisseria gonorrhoeae, but penicillin-resistant Neisseria gonorrhoeae is also resistant to tetracycline. It has a good antibacterial effect on Gram-negative bacteria such as Vibrio, Brucella, Campylobacter, and Yersinia, but has no antibacterial activity against Pseudomonas Aeruginosa.

It has a certain antibacterial effect on some anaerobic bacteria, but it is far inferior to metronidazole, clindamycin, and chloramphenicol, so it is not used clinically.

Moreover, there is cross-resistance among the same varieties. The mechanism of its action lies in that the drug can specifically bind to the A position of bacterial ribosome 30S subunit, preventing the connection of aminoacyl-－tRNA at this position, thus inhibiting the growth of peptide chain and affecting the synthesis of bacterial protein.

What are the precautions when using tetracycline hydrochloride?

1. Cross-allergic reaction: people who are allergic to one tetracycline drug are allergic to other tetracycline drugs.

2. Disturbance to diagnosis (1) When measuring the concentration of catecholamine in urine (Hingerty method), because of the interference of tetracycline to fluorescence, the measurement result is on the high side. (2) This product can increase the measured values of alkaline phosphatase, blood urea nitrogen, serum amylase, serum bilirubin, and serum aminotransferase (AST, ALT).

3. During long-term medication, a regular follow-up examination of blood routine and liver and kidney function should be conducted.

4. When using this product, you should drink enough water (about 240ml) to avoid esophageal ulcers and reduce gastrointestinal irritation.

5. This product should be taken orally on an empty stomach, that is, 1 hour before or 2 hours after a meal, in order to avoid the influence of food on absorption.

6. Use with caution or avoid the application when the following situations exist. (1) Because this product can cause liver damage, it is not suitable for patients with original liver diseases to use this kind of drug. (2) Because this product can aggravate azotemia, it is not suitable to use this kind of drug for the existing renal function damage. If there are indications, it should be carefully considered, and it should be reduced according to the degree of renal function damage.

7. In the treatment of sexually transmitted diseases, if it is suspected that there is spirochete infection at the same time, dark-field microscopy and serological examination should be performed before medication, the latter once a month, at least 4 times.

How to choose more products

Send your Inquiry for more details, Click email：allen@faithfulbio.com Now.

You can also contact me via WhatsApp：+86 13137770562

A variety of shipping methods for you to choose

Disclaimer: The articles published on this site are mainly used to promote academic exchanges and learning, and do not mean that this site agrees with its views or confirms the authenticity of its contents. Please filter carefully. If you believe this article is infringing, please contact the administrator. We are not responsible for the consequences of using the information and services on this website.

Note: This compound should be used for research purposes only. These claims have not been evaluated by the Food and Drug Administration. Please consult your doctor and learn about available studies before using them. This product is not intended to diagnose, treat, cure or prevent any disease.

Hot Tags: tetracycline hcl powder cas 64-75-5, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China