Raw material Thiamphenicol is a bacteriostatic antibiotic derived from chloramphenicol. It is effective against several gram-positive and gram-negative bacteria and is commonly used in researching protein synthesis and selecting for chloramphenicol-resistant transformed cells or the bacterial CAT gene. It can be used against uncomplicated gonorrhea infections and chancroid. Thiamphenicol functions by binding the 50s ribosomal subunit and inhibiting the synthesis of proteins by blocking aminoacyl-tRNA from attaching to the A site. It works by the same mechanism as chloramphenicol but is about three times as potent.
| Molecular formula |
|
|
|
Item |
Standard |
Test Results |
|
Appearance |
White or almost white powder |
Complies |
|
Identification |
HNMR and HPLC retention time. |
Complies |
|
Melting point |
163℃ ~ 168℃ |
163.8℃ |
|
Solibulity |
Practically insoluble in water,sparingly soluble In dimethylformamide,very slightyly souluble in methanol |
Complies |
|
Total Impurities |
≤1.0% |
0.1% |
|
Impurity A |
≤0.5% |
0.02% |
|
Impurity B |
≤0.5% |
0.01% |
|
Any Other Impurity |
≤0.5% |
0.03% |
|
Sulphated ash |
≤0.3% |
0.2% |
|
Loss on drying |
≤ 0.5% |
0.2% |
|
Heavy metals |
<10ppm |
5ppm |
|
Pb |
<1ppm |
0.03ppm |
|
Total bacteria count |
<1000 cfu/g |
1.8 cfu/g |
|
Yeast and Moulds |
<100 cfu/g |
0.35 cfu/g |
|
Escherichia Coli |
Negative |
Negative |
|
Salmonella |
Negative |
Negative |
|
Assay |
≥98.0 % |
99.3% |
| Conclusion： |
Conform with enterprise specification . |
What are antibiotics? How to take Thiamphenicol correctly?
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
Raw material Thiamphenicol is a broad-spectrum antibiotic of chloramphenicol, which has a stronger effect on Gram-negative bacteria than positive bacteria. Before using this product, please follow the doctor's instructions and read the information on the medicine bag. Take Thiamphenicol according to the dose given by the doctor. Do not increase or decrease the dose or stop taking the medicine before the specified time without consulting the doctor. This product can be taken on an empty stomach. It is recommended to take Thiamphenicol 1 hour before meals or 2 hours after meals. Swallow the whole Thiamphenicol capsule or capsule with the help of water. To take the form of dry syrup, mix the drug with water according to the recommended dose. Use a measuring cup to mix an appropriate amount of water. It is best to take Thiamphenicol at the same time every day. If you forget to take thiamphenicol, if it is not too close to the next time, please take it again immediately after remembering. If it is close, ignore it and do not double the dose. We suggest that friends who take Thiamphenicol for a long time for some conditions should have regular blood tests. The action is carried out by doctors to monitor the patient's health and the effectiveness of antibiotics. Finally, you should store this product at room temperature, dry, and away from light. Keep the medicine out of the reach of children.
What is the reaction of thiamphenicol mixed with other drugs? What hazards will this product bring?
The use of Raw material Thiamphenicol with products that inhibit bone marrow function increases the risk of bone marrow decline
The role of anticoagulant drugs, antidiabetic drugs, or anticonvulsant drugs (such as phenytoin) is increased. The combination of thiamphenicol with phenobarbital or rifampicin increased the metabolism of thiamphenicol. At the same time, taking this product alone will also have a variety of side effects due to physical characteristics, including Headache, nausea, gas, diarrhea, sprue, tongue inflammation (glossitis), and mood changes, In addition, clinical studies have found that long-term use of thiamphenicol increases the risk of bleeding and optic neuritis. If these side effects do not improve or worsen, consult your doctor. If you have serious side effects or allergic reactions to this product, please see a doctor immediately, which is characterized by swollen lips or eyelids, itchy skin rash, or dyspnea.
What is the market prospect of thiamphenicol?
Thiamphenicol (also known as thiophenicol and dextrosulphenidol) is an antibiotic. It is the methyl-sulfonyl analog of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, it is insoluble in water but highly soluble in lipids. It is used in many countries as a veterinary antibiotic but is available in China, Morocco, and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with aplastic anemia. Thiamphenicol is also widely used in Brazil, particularly for the treatment of sexually transmitted infections and pelvic inflammatory diseases. Unlike chloramphenicol, thiamphenicol is not readily metabolized in cattle, poultry, sheep, or humans, but is predominantly excreted unchanged. In pigs and rats, the drug is excreted both as a parent drug and as thiamphenicol glucuronate (FAO, 1997).
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
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