What is Metronidazole ?
Metronidazole is an antibacterial drug, belonging to nitroimidazole derivatives, which can effectively kill sterilized insects and resist anaerobic bacteria.
It can interfere with the DNA of bacteria and protozoa, thus inhibiting the formation of nucleic acids. Metronidazole is the first choice for the treatment of vaginal trichomoniasis. In addition, it can also kill amoeba in intestines and tissues.Metronidazole powder is characterized by low toxicity, high curative effect and wide clinical application.
It appears as white or yellowish crystal or crystalline powder; It is slightly smelly, bitter and slightly salty. Slightly soluble in water or chloroform. Metronidazole is a nitrogen-containing heterocyclic compound, which is alkaline and has low water solubility. According to the principle of prodrug, it is made into phosphate potassium salt, which has increased water solubility and can be used as injection.
| Product name |
Metronidazole |
| CAS | 443-48-1 |
| Molecular formula | C6H9N3O3 |
| Molecular weight | 171.15 |
| EINECS Number | 207-136-1 |
| melting point | 159-161 °C (lit.) |
| boiling point | 301.12°C (rough estimate) |
| density | 1.3994 (rough estimate) |
| flash(ing) point | 9℃ |
| refractive index | 1.5800 (estimate) |
| Storage condition | Keep in dark place,Inert atmosphere,Room temperature |
What are the indications for metronidazole ?
Metronidazole was first discovered in 1962 to have a very effective therapeutic effect on anaerobic infection, and was later listed as the first choice drug for anaerobic infection. Clinical application of metronidazole;
1. Against trichomonas vaginalis. Metronidazole powder is a specific drug for trichomonal vaginitis in the world at present.
2. Prevent infection after surgery. Preventive use of metronidazole before and after reoperation can significantly reduce the infection rate of wounds. It is mainly suitable for anti-infection of appendectomy, colorectal surgery, abdominal infection and so on.
3. Treatment of peptic ulcer. Metronidazole can protect mucosa and promote mucosal regeneration. It can achieve ideal cure rate and ulcer healing rate for gastric and duodenal ulcers.
4. Treat chronic cough with abscess caused by bronchopneumonia infection. which can quickly control infection and improve self-conscious symptoms. 5. Hyperlipidemia. Metronidazole powder has obvious hypolipidemic effect,
6. Treat tetanus. It is reported that metronidazole has a very good therapeutic effect on tetanus, even higher than penicillin. Debridement, injection of antitoxin and intravenous rehydration were carried out while metronidazole was applied.
7.Oral diseases.
Periodontitis, gingivitis, periodontal abscess, upper frontal sinusitis, tonsillitis, etc.
Product Specification
| Item | Specifications | Result |
|
Appearance |
White crystalline powder |
Confirm |
|
Assay |
≥99.0% |
99.56% |
|
Related substances |
≤1.0% |
0.05% |
|
Loss on drying |
≤0.5% |
0.18% |
|
Residue on ignition |
≤0.1% |
99.56% |
|
Chloride |
≤0.014% |
Confirm |
|
Heavy Metals |
≤20ppm |
Confirm |
|
Clarity of solution |
Conform to standard |
Confirm |
|
Microbial Limit |
≤20ppm |
Confirm |
| Conclusion: The test results are conformed to the in-house specification | ||
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Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
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