Amprolium HCl powder can be combined with other products to make water-soluble powders or premixes for the prevention of coccidiosis in laying chickens. In addition, high-quality Amprolium Hydrochloride is effective against chicken Eimeria, soft and heap Eimeria, lamb and calf Eimeria. If this product is made into a composite formulation with raw materials such as Ethopabate and SULFAQUINOXALIN, it can expand the anti coccidiosis spectrum and enhance the anti coccidiosis effect. In clinical practice, if Amprolium Hydrochloride is used in combination with Sulfaquinoxaline for concurrent bacterial infections, it will have a good inhibitory effect.
| Molecular formula |
|
|
|
ITEMS OF ANALYSIS |
SPECIFICATIONS |
RESULT |
|
Appearance |
White powder |
Complies |
|
Content (calculated on the dried basis) |
97.0%–101.0% |
99.5% |
|
Identification |
Should me the requirement |
Complies |
|
Loss on drying |
≤ 1.0% |
0.4% |
|
Heavy metals |
≤ 10ppm |
Complies |
|
Total plate count |
≤ 1000cfu/g |
Complies |
|
Conclusion |
Complies with the USP 43 standard. |
What are the pharmacological effects of this product?
The chemical structure of Amprolium is similar to that of thiamine, and it is a traditional anti coccidian drug with good anti coccidial effects. Currently, it is still one of the main anti parasitic products. White or off white Amprolium HCl powder is easily soluble in water. If mixed with feed, especially under neutral conditions, this product can slowly decompose. In clinical experiments, we found that Amprolium Hydrochloride competitively inhibits the uptake of thiamine by nematodes. In cells, thiamine is synthesized into thiamine pyrophosphate, which participates in the oxidative decarboxylation of α - ketoacids during glucose metabolism. It is a coenzyme in the α - ketoacid dehydrogenase system. Due to the lack of the hydroxyethyl group of thiamine, aminophylline cannot be pyrophosphate, which hinders many reactions and hinders the sugar metabolism process in the parasite cells, thereby inhibiting the development of nematodes. For chicken coccidiosis, the peak period of action is often to prevent the formation of merozoites in the first generation. In addition, this product also has inhibitory effects on the sexual cycle of coccidiosis and the formation of egg sacs by spores.
What are the advantages of this product?
Amprolium is a thiamine-like substance, which inhibits thiamine transport of coccidia by inhibiting thiamine absorption and carbohydrate synthesis. Its advantages are as follows: ① It has obvious preventive effect on E.tenella and E.necatrix, and has inhibitory effect on E.maxima and E.mivatti. ② Among all kinds of anticoccidial drugs, this variety has the highest safety. ③ This product is stable in nature, and can be mixed with various vitamins, minerals and antibacterial drugs. However, it should be noted that this product will slowly decompose in broiler feed, so it is suggested to be used now.
In addition, Aprolin is suitable to be combined with other drugs to make water-soluble powder or premix, and the effect will be multiplied. For example, This product, together with Ethopabate and Sulfaquinoxaline, is made into a compound preparation to expand the anticoccidial spectrum and enhance the anticoccidial effect. The combination of this product and Sulfaquinoxaline also has a good inhibitory effect on concurrent bacterial infection.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Amprolium HCl powder etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.
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