Flumequine Veterinary​ CAS 42835-25-6
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Flumequine Veterinary​ CAS 42835-25-6

Flumequine Veterinary​ CAS 42835-25-6

Product Name:Flumequine veterinary
CAS NO.: 42835-25-6
Molecular Formula:C14H12FNO3
EINECS.NO:255-962-6
Synonym:Aoyribe;Apurone;Fantacin;Flumeguine;FLUMEQUIN;Flumural;Imequyl;Quinolone;R 802;Flumigal
Lead Time:1-3 days
Shipping:DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea etc
Store & Shelf life:Cool & dry place;36 months
Other:There are warehouses in the United States, Australia and Germany

Description

what is Flumequine veterinary​?

Flumequine veterinary​ a synthetic fluoroquinolone antibioticused to treat bacterial infections. It is a second-generation quinolone animal specific antibacterial drug synthesized artificially, and currently the only broad-spectrum antibacterial veterinary drug that is not shared with humans. It is a substitute for norfloxacin and has strong bactericidal activity, with good therapeutic effects on animal bacterial diseases. Flumequine was used in veterinarian medicine for the treatment of enteric infections (all infections of the intestinal tract), as well as to treat cattle, swine, chickens, and fish.

 

MF of Flumequine veterinary CAS 42835-25-6

Product name

Flumequine

CAS

42835-25-6

Molecular formula

C14H12FNO3

Molecular weight

261.25
EINECS 255-962-6

Appearance

White to off-white powder

Melting point 

253-255°C
Storage Sealed in dry,Store in freezer, under -20°C
Density 1.45±0.1 g/cm3(Predicted)

What is Flumequine veterinary​ used for?

bacterial respiratory diseases in livestock

Mainly used for bacterial respiratory diseases in livestock and poultry, Escherichia coli, dysentery, salmonellosis, typhoid fever, avian cholera, staphylococcal infectious rhinitis, etc.
Escherichia coli disease, as well as diseases of the genera Pseudomonas and Streptococcus in aquatic animals, have a strong inhibitory effect on Aeromonas hydrophila.

If you need it, pls click e-mail sales1@faithfulbio.com

 

what is the history of Flumequine veterinary​?

Since the 1970s, Flumequine veterinary​ has been widely used in livestock, poultry, and aquaculture in countries such as the European Union and Japan. It has shown good efficacy in treating diseases caused by various Gram negative bacteria, especially those caused by Escherichia coli, Mycoplasma, and Aeromonas hydrophila in livestock, poultry, and aquatic animals. It was gradually developed and listed in China in the late 1990s, mainly for the prevention and treatment of bacterial infectious diseases of salmon, trout, shrimp, eel, pigs, chickens, etc. Due to its ability to inhibit bacterial DNA helicase, wide antibacterial spectrum, high efficiency, low toxicity, strong tissue penetration, and no anesthetic effect, Flumequine have become one of the most important anti infective drugs in veterinary clinical practice and aquaculture, and are widely used for treatment, prevention, and growth promotion. Due to its drug resistance and potential carcinogenicity, the European Union, Japan, and China have all established maximum residue limits in their tissues (100ppb in both China and the European Union). At present, the main detection methods for Flumequine include fluorescence spectrophotometry, enzyme-linked immunosorbent assay (ELISA), and liquid chromatography. ELISA has become a routine screening method due to its high sensitivity and easy operation.

 

What is the mechanism of action of Flumequine veterinary​?

Flumequine inhibit the deoxyribonucleic acid DNA gyrase of bacteria Its main function is to inhibit the deoxyribonucleic acid (DNA) gyrase of bacteria, interfere with the synthesis of deoxyribonucleic acid (DNA) proteins, prevent cell division, and thus play a bactericidal role

 

Product Specification

Items

Specifications

Results

Appearance

White or almost white crystalline powder, odorless

Conforms

Identification

spectrum Conforms to Structure Conforms

Loss on drying

≤0.5%

0.1%

 

impurity A ≤0.5%

0.32%
 

impurity B ≤0.5%

0.26%
Related substances

unspecified impurities ≤0.1%

0.08%
 

total impurities ≤1.0%

comforms

Residue on ignition

≤0.1%

0.03%

Heavy metals

≤10ppm

<10ppm

Assay (HPLC)

99.0%~101.0%

99.4%

Conclusion:Conform with specification and qualified.

 

What are the in vitro studies of Flumequine veterinary​?

Flumequine veterinary​ inhibits topoisomerase II in eukaryotes, which is the reason why double stranded DNA cleavage reactions and bacterial helices are affected. The inhibitory effect of FL on topoisomerase II is highly correlated with its impact on bacterial helices. The minimum inhibitory concentration range of Flumequin for 12 clinical A. salicida bacterial strains is 0.06 μ g/mL to 32 μ g/mL. Flumequine has a high E (max) value of 16 for most drug-resistant bacterial strains, which is an important contribution to eliminating drug-resistant phenotypes. The Flumequine accumulation test confirms that high E (max) values are associated with very low levels of accumulation

 

How and where to buy Flumequine veterinary​ wholesale?

We have 8 years of experience in selling legal scientific research drugs and have a good reputation, making us a trustworthy partner.
We ensure the quality of our products through independent experimental testing, and every customer is our VIP.

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A variety of shipping methods for you to choose

Transportation Time

Shipping method

Cargo weight requirements

Advantage

3-7 days

DHL, Germany DHL, Germany DPD,
UPS, USPS,FedEx, TNT,EMS

Suitable for under 50kg.
International door to door express

We have warehouses in Germany and California, USA,
and customers in Europe and America can
enjoy sending goods directly from these two places.

7-15 days

By Air

Suitable for more than 50kg.
fast and cheaper for large order

15-60 days

By Sea

Suitable for more than 500kg.
Cheapest shipping way

 

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Note: The product is for research use only and is not intended for diagnosis, treatment, disease prevention, etc.

 

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