Product description

Fludarabine Phosphate Powder can improve the remission rate of disease by promoting the apoptosis of tumor cells. Its pro-apoptotic pathway is mainly achieved by regulating the following pathways: death receptor pathway, mitochondrial pathway, P53, ceramide, BCL-2 family and some apoptosis promoters and inhibitors. Fludarabine phosphate for the treatment of chronic lymphocytic leukemia. Fludarabine Phosphate is converted into F-ara-ATP within the cell and then bound to DNA in its own restricted way.
Fludarabine phosphate is rapidly dephosphorylated to fludarabine phosphate, which can be taken up by cells and then phosphorylated by intracellular deoxycytidine kinase to become the active triphosphate 2F-ara-ATP. The metabolite can inhibit DNA synthesis by inhibiting nucleotide reductase, DNA polymerase α, δ and Σ, DNA primer enzymes and DNA ligase.

Send your Inquiry for more details, Click email:sales4@faithfulbio.com
COA
| Test | Specifications | Result |
| Assay | 99%~101% | 99.5% |
| Appearance: | White Powder | Complies |
| Odor &taste: | Characteristic | Complies |
| Loss on drying %: | ≤6.0% | 3.83% |
| Heavy metals ppm: | <10ppm | Complies |
| As | ≤3.0 ppm | Complies |
| Pb | ≤3.0 ppm | Complies |
| Cd | ≤0.5 ppm | Complies |
| Conclusion | Conform with enterprise specification | |

Density 2.4± 0.1g /cm3
Boiling point 864.2±75.0 °C at 760 mmHg
Melting point 203 °C(dec.)
Molecular formula C10H13FN5O7P
Molecular weight 365.212
Flash point 476.4±37.1 °C
Send your Inquiry for more details, Click email:sales4@faithfulbio.com
What is Fludarabine Phosphate Powder used to treat?
A drug used to treat adults with B-cell chronic lymphocytic leukemia that has not responded to treatment with other anticancer drugs or that has gotten worse. It is also being studied in the treatment of other types of cancer.
What class of drug is fludarabine phosphate?
Fludarabine phosphate is a purine nucleoside antitumor agent, which inhibits adenosine deaminase. It is mainly used to treat chronic lymphocytic leukemia. Dose-limiting myelotoxicity, nausea and vomiting, and raised liver enzymes were observed during early clinical studies.
Send your Inquiry for more details, Click email:sales4@faithfulbio.com

why choose us
Our Factory


Package

Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email:sales4@faithfulbio.com
Hot Tags: fludarabine phosphate powder cas 75607-67-9, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China






