What is Theaflavin ?
Theaflavin is the oxidation product of polyphenols produced in the process of tea fermentation, which mainly exists in black tea and is the key component to give black tea a golden, bright and unique taste.Theaflavin powder is known as "soft gold in tea", and the content of theaflavins in black tea is only 0.5%-2.0%. Theaflavins are the general name of many compounds formed by the oxidation of polyphenols.

| Product name |
Theaflavin |
| CAS | 4670-05-7 |
| structural formula | C29H24O12 |
| molecular weight | 564.49 |
| melting point | 237-240 °C (decomp)(Solv: water (7732-18-5)) |
| boiling point | 1079.6±65.0 °C(Predicted) |
| Acidity coefficient (pKa) | 6.65±0.20(Predicted) |
| density | 1.777±0.06 g/cm3(Predicted) |
| Storage condition | -20°C |
How is Theaflavin powder extracted ?
Theaflavin powder comes from the product of tea fermentation, and its preparation process is as follows: weighing 100g of tea powder, adding 1000ml of deionized water (90℃) for leaching for 30min, and taking out the leaching solution; Then add 500ml deionized water (90℃) for leaching for 30min;; The extracts were combined, filtered with 300 mesh filter cloth and treated with 0.05um ceramic membrane to obtain theaflavin microfiltration.
Pumping theaflavin microfiltration from the heavy phase inlet into a two-stage centrifugal extractor in series, and simultaneously pumping a solution with a volume of 1/2 of the feed liquid of theaflavin microfiltration, collecting the light phase outlet liquid, vacuum concentrating at a low temperature of 40 DEG C, and spray drying to obtain Theaflavin powder.

What are the effects and functions of Theaflavin ?

As a natural active ingredient in tea, this product usually has antioxidant, blood lipid regulating, anti-inflammatory, cardiovascular protection and antibacterial effects. Its medical value has been paid more and more attention in recent years, but its specific application needs to be evaluated in combination with individual conditions.
1, antioxidant
Theaflavin powder has a strong ability to scavenge free radicals, and can help delay cell aging by inhibiting lipid peroxidation and reducing DNA oxidative damage. Its antioxidant activity is remarkable in vitro experiments, which may have an auxiliary effect on preventing diseases related to oxidative stress.
2, regulating blood lipids
The composition can inhibit intestinal cholesterol absorption and promote bile acid excretion, thereby reducing serum total cholesterol and low density lipoprotein levels. Animal experiments show that it can improve lipid metabolism disorder.
3. Anti-inflammatory
It can reduce inflammatory reaction by inhibiting the expression of inflammatory mediators such as COX-2 and TNF-α. Studies have confirmed that it can alleviate intestinal mucosal injury in experimental colitis model and may improve chronic inflammatory diseases.
4. Protect the cardiovascular system
It helps to maintain the health of cardiovascular system by improving vascular endothelial function, inhibiting platelet aggregation and regulating blood pressure. It can enhance that bioavailability of nitric oxide and prevent the formation of atherosclerotic plaque.
5, antibacterial
Theaflavin powder has inhibitory effect on pathogenic bacteria such as Staphylococcus aureus and Helicobacter pylori, and its mechanism involves destroying the integrity of bacterial cell membrane and interfering with the activity of metabolic enzymes. In vitro experiments show that the combination with antibiotics can enhance the antibacterial effect.
Product Specification
| Items | Specifications | Results | |||
| Assay | 10:1,20:1,50:1 | Complies | |||
| Apperence | Brown Powder | Complies | |||
| Particle Size | 100% pass 80 mesh | Complies | |||
| Oder | Characteristic | Complies | |||
| Taste | Characteristic | Complies | |||
| Loss on Drying | ≤5.0% | 2.20% | |||
| Residue on Ignition | ≤0.1% | 0.05% | |||
| Residual | ≤0.1% | Complies | |||
| Residual Ethanol | ≤0.5% | Complies | |||
| Heavy Metal | ≤ 10.0 mg/kg | Complies | |||
| Pb | ≤ 2.0 mg/kg | Complies | |||
| As | ≤ 1.0 mg/kg | Complies | |||
| Hg | ≤ 0.1 mg/kg | Complies | |||
|
Total Plate Count |
<1000cfu/g |
75cfu/g |
|||
|
Yeast & Mold |
<100cfu/g |
15cfu/g |
|||
|
E. Coli |
Negative |
Absent |
|||
|
S. Aureus |
Negative |
Absent |
|||
|
Saimonella |
Negative |
Absent |
|||
|
Pesticides |
Negative |
Absent |
|||
| Conclusion: The test results are conformed to the in-house specification | |||||
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Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
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