Phloretin Powder CAS 60-82-2

Phloretin belongs to flavonoids, which is a natural active substance in the juice of fruits and vegetables such as apples and pears, and can protect plants from ultraviolet rays. Dihydronaringenin, as a functional raw material of cosmetics, has been widely concerned by the beauty industry because of its extensive biological properties. The phloretin powder provided by our company is reddish powder, soluble in methanol, ethanol and acetone, and almost insoluble in water.

What are the functional applications of Phloretin?

Phloretin is a new natural skin whitening agent recently developed at home and abroad, which is often used in facial mask, skin care cream, emulsion and essence. Clinical studies have found that it can prevent sugar from entering epidermal cells, thus inhibiting the excessive secretion of sebaceous glands and treating acne with exuberant secretion; It can inhibit the activity of melanocytes and dilute various skin spots.
Compared with similar natural ingredients arbutin and kojic acid, phloretin with the same concentration has better inhibitory effect on tyrosinase, and when it is compounded with arbutin or kojic acid, it can greatly improve the inhibitory rate on tyrosinase, thus achieving whitening effect. After comparing the contents of phloretin in different plants, the natural phloretin powder is mainly distributed in the peels and roots of juicy fruits such as apples and pears. Perhaps for this reason, this product has a very strong moisturizing effect and can absorb 4 ~ 5 times its own weight of water. Sufficient water molecules can promote the absorption and utilization of other functional factors in the formula, so that it can play a better role. This product has a strong antioxidant function, which can remove free radicals in the skin, and the antioxidant concentration of oil is between (10 ~ 30) × 10-6.

What are the other activities of Phloretin?

Phloretin is a dihydrochalcone containing polyhydric phenol. In animal experiments, we can observe that Dihydronaringenin inhibits the active transport of glucose into cells through SGLT1 and SGLT2, although the inhibition is weaker than its sugar ligand phloridzin. In the monkey experiment, we can find that 60-81-1 Phlorizin can be completely converted into phloretin by hydrolase in the small intestine. The most important discovery in this process is to inhibit the absorption of glucose by small intestine and the reabsorption of glucose by kidney. In addition, Phloretin can also inhibit various urea transporters. When combined with high-protein diet, it causes urea reduction and has diuretic effect. As we said earlier, phloretin is very effective in anti-oxidation, moisturizing, light pigmentation and anti-inflammation. This is not only because phloretin has strong oxidation resistance and photoprotection (it can eliminate the increase of free radicals in skin and the damage of cells and DNA caused by ultraviolet rays), but also because compared with other traditional products, phloretin powder can inhibit the activities of matrix metalloproteinases (MMP-1) and elastase, which can degrade the connective tissue of skin and play an important role in the photoaging process of skin.

What are the applications of Phloretin in food addition and nutritional supplement?

Phloretin can be directly absorbed by human body, but there are few phloretin naturally occurring in plants. Phloretin mostly exists in the form of its glycoside derivative-phlorizin. Phlorizin absorbed by human body can not enter the circulatory system until its glycoside group is removed from the gastric mucosa to generate phloretin, thus exerting its efficacy.

Phloretin is not only has whitening and anti-aging effects in cosmetics and health products. At the same time, in the field of food supplement applications, phloretin is also a very unique natural bitterness inhibitor and flavor improver, which can suppress bitterness and other discomforts in food and improve taste; Reducing the odor of high-intensity sweeteners and masking their unpleasant flavors can be widely used in beverages, tablets, gummies, and other varieties, with broad market prospects.

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