What is Madecassic acid powder?
Xi'an Faithful BioTech Co., Ltd. is based in Xi'an, origin of the ancient Silk Road. Benefiting from the city's sound logistics facilities and ample stock of specialty chemicals, we have developed into an all-round fine chemical provider for international buyers. Madecassic acid powder, supplied by China Nootropic Ingredients & Pharmaceutical API Powder Manufacturer, is a triterpenoid compound extracted from centella asiatica with CAS number 18449-41-7. It appears as off-white to beige powder, commonly tested by HPLC with available purity grades of 80%, 90% and 98%. This plant-derived raw material is widely adopted in skin care formulations. It features low water solubility and can dissolve in DMSO as well as mixed solvent of ethanol and chloroform.
What are the applicable research scenarios for Madecassic acid powder?
Madecassic acid powder (CAS 18449-41-7) is derived from Centella asiatica extract and is widely used in various skincare formulations. Often utilized in conjunction with other triterpene components from Centella asiatica, it helps protect the skin barrier and maintain skin comfort, making it suitable for the development of diverse topical care products. Available in various purity specifications, it caters to needs ranging from laboratory formulation testing to bulk raw material supply, serving both skincare R&D and raw material trade requirements.
COA
| Item | Specification | Result |
| Appearance | Off-white to beige powder | Complies |
| Identification (HPLC) | Consistent with reference standard | Complies |
| Assay(HPLC) | ≥98.0% | 98.6% |
| Loss on drying | ≤1.0% | 0.42% |
| Heavy metals(Pb) | ≤10 ppm | <10 ppm |
| Total plate count | ≤1000 CFU/g | Complies |
| Conclusion | Conform with enterprise specification | |
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Density 1.23±0.1 g/cm³ (Predicted)
Boiling point 641.7±55.0 °C (Predicted)
Melting point 270°C (dec.)
Molecular formula C30H48O6
Molecular weight 504.71
Flash point 355.9±28.0 °C
Exact mass 504.345093
PSA 118.22000
LogP 4.321 (est)
InChIKey PRAUVHZJPXOEIF-MRQYELSVNA-N
What is the mechanism of action of Madecassic acid powder?
Madecassic acid powder participates in governing NF-κB signal transmission, decreases the outflow of pro-inflammatory compounds, alleviates skin sensitivity brought by external triggers and soothes skin redness and discomfort.
Madecassic acid traps free radicals generated from environmental stress, impedes lipid peroxidation responses, and reduces oxidative load exerted on epidermal cells from outside irritants.
This active constituent accelerates the generation of structural proteins present in the stratum corneum, solidifies the interlocked framework of the skin protective layer, minimizes transepidermal water loss and maintains the normal performance of skin barrier.
While functioning together with other triterpenoid substances extracted from Centella asiatica, it modulates epidermal cell regeneration cycles, accelerates the rehabilitation of damaged epidermal tissue and improves rough skin surface condition.
Madecassic acid limits the catalytic capacity of matrix metalloproteinases (MMPs), retards the breakdown of collagen fibrils and sustains the stable state of fibrous networks within skin tissue.
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Shipping Methods
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS |
Suitable for under 50kg. International door to door express |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order |
|
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
FAQ
01. In what applications is Madecassic acid primarily used?
It is widely used in the development of various skincare formulations, often in combination with Asiatic acid and Asiaticoside. Suitable for a range of topical care products, it is used in raw material trading as well as in laboratory formulation development.
02. What are the key functions of Madecassic acid?
Madecassic acid soothes skin discomfort caused by external factors, scavenges free radicals, and alleviates oxidative stress. It also helps strengthen the skin barrier, maintains the stability of the skin's fibrous structure, and aids in improving rough skin texture.
03. What are the storage requirements for Madecassic acid?
Madecassic acid powder should be stored in a sealed container in a cool, dry place; low-temperature storage is recommended for high-purity reference standards to prevent the degradation of active ingredients.
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Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.
Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.
Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.
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