What is Dihydrocapsaicin?
Capsaicin is composed of more than ten analogues such as capsaicin (60-70%) and Dihydrocapsaicin (20-30%), but capsaicin is generally used in medical research. Because the structure and physical and chemical properties of capsaicin analogues are very close, it is difficult to separate monomer compounds. Its content has a great influence on the overall spicy quality and taste of pepper, and it is one of the important indexes to evaluate the quality of pepper. Using traditional chemical analysis methods, such as high performance liquid chromatography and ultraviolet spectrophotometry, to determine the content of this product is destructive analysis, and the experimental drugs used are expensive, the experimental operation is complicated, time-consuming and laborious. Near infrared spectroscopy analysis technology has the advantages of fast analysis speed, no damage to samples, simple operation, good stability and high efficiency, and has been widely used in the quality analysis of fruits and vegetables.

| Product name | Dihydrocapsaicin |
| CAS | 19408-84-5 |
| Molecular formula | C18H29NO3 |
| Molecular weight | 307.43 |
| EINECS | 606-308-7 |
| melting point | 62-65 °C(lit.) |
| boiling point | 497.4±35.0 °C(Predicted) |
| density | 1.026±0.06 g/cm3(Predicted) |
| solubility | Insoluble in water |
| Storage condition | Sealed in dry,2-8°C |
What are The source and main function of Dihydrocapsaicin ?

Dihydrocapsaicin has analgesic, antipyretic and antipruritic effects, and can be used according to its own situation.
1.relieve pain
It can stimulate local nerves, relieve pain and help the body recover.
2. clear away heat
It can stimulate the body's heat-generating system, accelerate the body's metabolism, for example, the body has fever symptoms, which can alleviate the effect.
3. stop itching
Dihydrocapsaicin can relieve itching and promote blood circulation, such as eczema or psoriasis.
In addition to the above-mentioned functions and effects, it can also achieve anti-inflammatory effects, such as relieving diseases such as pain caused by rheumatism.
The synthetic methods of dihydrocapsaicin are mainly divided into chemical synthesis and natural extraction, as follows:
1.chemical synthesis method
Starting material
Dihydrocapsaicin was synthesized from furfural and methyl isopropyl ketone by four-step condensation reaction.
Reaction step
Firstly, carrying out condensation reaction to generate an intermediate product;
Then the target product 1 was finally obtained through subsequent reaction steps such as hydrogenation and deprotection.
Advantages and limitations
Advantages: high yield and purity, suitable for large-scale production;
Limitations: There are potential safety hazards and potential environmental problems.
2.the natural extraction method
extractive technique
Supercritical fluid extraction: using supercritical co to extract dihydrocapsaicin from pepper quickly and efficiently, which is environmentally friendly and has good separation effect;
Solvent extraction: capsaicin is extracted by methanol, ethanol and other solvents, followed by crystallization, purification and separation.
Purification and separation
The dihydrocapsaicin monomer with purity ≥96% can be obtained by single separation of the extract by medium pressure liquid chromatography (HPLC).
Some methods are combined with vacuum distillation, extraction and other steps for further purification.

Product Specification
| Items | Specifications | Results |
|
Appearance |
White Powder / Off white powder |
Conforms |
| Purity | 98% -101% | 99.32% |
|
Heavy Metal |
≤ 10.0 mg/kg |
Complies |
|
Pb |
≤ 2.0 mg/kg |
Complies |
|
As |
≤ 1.0 mg/kg | Complies |
|
Hg |
≤ 0.1mg/kg | Complies |
|
Total Plate Count |
≤1000cfu/g |
<10cfu/g |
|
Yeast &Mold |
≤100cfu/g |
<20cfu/g |
|
E.Coli. |
Negative |
Negative |
|
Salmonella |
Negative |
Negative |
| Conclusion: The test results are conformed to the in-house specification | ||
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Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
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