Oxytocin Powder CAS 50-56-6

Oxytocin powder comes from Greek words"ὀξύς(oxys)" and "τόκος(tocos)", meaning "rapid production". Therefore, it has the function of contracting uterus and accelerating the delivery process. In addition, both men and women secrete oxytocin, which not only has a place in obstetrics, but also plays a role in the brain, affecting our emotions and social behavior.

Why is oxytocin called the companion of obstetricians?

Oxytocin, as a uterine contraction product, can be extracted from the posterior pituitary gland of animals or chemically synthesized. The chemical synthesis product contains no vasopressin, has no pressor effect, has a selective excitation effect on uterine smooth muscle, and strengthens its contraction. The uterus in labor is most sensitive to oxytocin (increased estrogen secretion). A small dose of oxytocin can selectively excite uterine smooth muscle, strengthen the rhythmic contraction of the smooth muscle at the bottom of uterus, make the contraction property similar to that of natural delivery, and maintain its enthusiasm and symmetry,Therefore, it is clinically used for expedite child delivery or inducing labor.

 

How to prevent postpartum hemorrhage?

 

In 2017, the American College of Obstetricians and Gynecologists (ACOG) guidelines for postpartum hemorrhage management pointed out that:
Oxytocin should be routinely used immediately after delivery; The first-line treatment for postpartum hemorrhage caused by uterine atony is oxytocin. In addition, the guide also puts forward the following opinions: at present, there is no more effective product than oxytocin in the treatment of postpartum hemorrhage caused by uterine atony. Oxytocin combined with some similar products does not increase efficacy. In addition, this product can also be used in cesarean section and uterine curettage to reduce bleeding; Used for abnormal abortion can promote the discharge of fetus or pregnancy residue.

Why is oxytocin called a hormone that intertwines love and hate?

Oxytocin (α-Hypophamine; Oxytocic hormone is a multifunctional hypothalamic peptide, which is helpful for childbirth, lactation and prosocial behavior. Oxytocin powder can also be used as a stress coping molecule with anti-inflammatory, antioxidant and protective effects, especially in the face of adversity or trauma. However, it is worth mentioning that some studies claim that oxytocin also has a "dark side", which may cause prejudice, anxiety and aggressive behavior. Its role in biological behavior is more complicated than usually thought, which may be related to the individual's growth environment and the original social relations. Under the interaction between genes and environment, it is more appropriate to describe it with "hormones intertwined with love and hate".

Our company specializes in producing and providing high-quality hormones and endocrine regulating raw materials such as oxytocin. If you are interested or have any purchasing plans, please leave us a message via email：sales6@faithfulbio.com

Suggestions on Pre - and Postpartum Care for Sows：

1. Oxytocin, as a hormone normally secreted by the body itself, changes with the physiological changes of the body at any time. If this product is used frequently, it will interfere with the re-secretion of autologous hormones, and hormones have a negative feedback regulation, which will cause endocrine disorder and make sows on the verge of weakness for a long time. And doing so will also produce dependence, leading to the problem of "inertia dystocia" in some pig farms.

2. The use of oxytocin can significantly increase the pain during delivery in sows, causing them to tremble and even shock throughout the body, and in severe cases, leading to uterine rupture; This can lead to a prolonged postpartum recovery period for sows, with frequent occurrences of postpartum anorexia, constipation, and infections. If the physical strength, appetite, lactation, and physical fitness of the sow are difficult to recover, breastfeeding and leading the newborn cubs will be very challenging.

3. Oxytocin can cause uterine tonic contraction, which is fast and powerful but not lasting, so oxytocin is only suitable for singleton animals. The pig is a multiparous animal, and after use, it will crush all the amniotic fluid at one time, resulting in the amniotic fluid being squeezed out at one time. Therefore, there is a characteristic when oxytocin is used, that is, it will speed up the process of giving birth and accelerate the discharge of amniotic fluid after use. Therefore, the first delivery is fast, and the second delivery is slow. As a result, some fetuses and placenta may stay in the uterus, which will worsen the intrauterine environment. Seriously lead to the death of sows.

4. Even if the sow or piglet does not die, the fetal umbilical cord will break prematurely in the uterus, and some fetuses will be squeezed excessively in the uterus, resulting in the increase of weak piglets.

Based on the above issues, the rational use of oxytocin is very important. Firstly, oxytocin should be used at the right time. Generally speaking, it should be used during normal childbirth after producing at least 5 piglets. During the process of sow delivery, when piglets have not been produced for 40 minutes, oxytocin should be used. Secondly, the dosage of oxytocin should be appropriate. It is recommended to use 2ml oxytocin for a single sow, and a maximum of 4ml oxytocin per multiparous sow. Based on uterine contractions and fetal discharge, it may be considered to repeat the use once every 1-2 hours, while combining other methods for assisted delivery.

If it is used for singleton animals, such as horses, cows, etc., it is only necessary to consider using the appropriate dose when it is impossible to give birth. Finally, during the feeding period, if the animal's milk is insufficient, oxytocin lactagogue can be considered when there is no other external cause.

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