What is Dasiglucagon?
Dasiglucagon is a globally first glucagon stabilized analogue peptide. Compared with the active control drug, for insulin induced hypoglycemia symptoms, the blood glucose level can be rapidly increased, the duration of blood glucose elevation is longer, and the effect is more significant. At the same time, it is a positive result of the pediatric phase III clinical study on the treatment of severe hypoglycemia in diabetes. It is used to treat severe hypoglycemia in children aged 6 years and over and adults with diabetes.
| Product name | Dasiglucagon |
| CAS | 1544300-84-6 |
| Molecular formula | C152H222N38O50 |
| Molecular weight | 3381.66 |
| EINECS Number | NA |
| melting point | NA |
| solubility | NA |
| Storage conditions | Avoid light and store at low temperatures |
| Appearance | White to off-white powder |
| boiling point | NA |
| Density | 1.50±0.1 g/cm3 |
Product Specification
| Item | Specification | Results |
| Appearance | White Powder | Complies |
| Identification | Positive | Complies |
| Assay | >98% | 99.50% |
| Ash | ≤5.0% | 2.55% |
| Loss on drying | ≤5.0% | 1.20% |
| Ignition residue | ≤2.0% | 0.25% |
| Heavy metals | ≤10ppm | Complies |
| Pb | ≤2.0ppm | Complies |
| As | ≤2.0ppm | Complies |
| Odor | Characteristic | Complies |
| Microbioiogical: | ||
| Total of bacteria | ≤1000cfu/g | 100cfu/g |
| Fungi | ≤100cfu/g | Complies |
| Salmgosella | Negative | Complies |
| Coli | Negative | Complies |
| Conclusion：Conform with enterprise | ||
Where is Dasiglucagon usually used?
Severe hypoglycemia: It has been approved by the US FDA for the treatment of severe hypoglycemia in patients with diabetes aged 6 years and above. It can stimulate the liver to release glucose, thereby increasing blood sugar concentration.
Congenital hyperinsulinemia (CHI): This is a rare pediatric disease characterized by persistent hypoglycemia due to excessive insulin production. It has shown significant reduction in the demand for intravenous glucose infusion in phase 3 clinical trials and is expected to become the first drug specifically developed for this rare disease in over 30 years.
In summary, Dasiglucagon is mainly used to treat severe hypoglycemia and congenital hyperinsulinemia. If you have more questions or need further information, please consult a professional doctor.
What are the effects of Dasiglucagon?
Treatment of severe hypoglycemia: it shows safety and effectiveness in the treatment of severe hypoglycemia in patients with type 1 diabetes (T1DM). Compared to glucagon, it performs better in reducing blood glucose recovery time or increasing blood glucose levels by 20.0mg/dL from baseline. In addition, compared to placebo, its effect is more significant.
Rapid elevation of blood sugar: Clinical Phase 2 trial results show that for insulin induced hypoglycemia symptoms, it can rapidly increase blood sugar levels, and the duration of blood sugar elevation is longer, with more significant effects.
Stability and Ready to Use Formulation: It has unique stability in liquid formulations and is suitable for ready to use therapy pens, making it convenient for patients to use.
Low immunogenicity: in a phase III clinical trial for 90 patients with type 1 diabetes, no treatment induced or treatment enhanced anti drug antibody was detected, indicating its low immunogenicity and good safety.
In summary, Dasiglucagon has significant efficacy in treating severe hypoglycemia, and has good stability and safety. If you have more questions or need further information, please consult a professional doctor.
How and where to buy Dasiglucagon wholesale?
Our products undergo experimental testing and are recognized by customers.
You can trust our order because we have a good record of selling legal educational drugs.
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
FAQ：
Q1:How about your after-sale service?
A1: We have profession team for loading, as well as the logistics team for documents. Our logistics team will send arrival notice for customers and keeping eyes for their feedback once received our cargoes. If any issue, we will solve it at once and our customers are always long term partners.
Q2:What is your delivery time?
A2:Usually we will arrange the delivery within 1 -3days.
Q3:Are you manufacture or trading company?
A3: We are manufacture & trader.
Disclaimer: The information provided on this website is for reference only and does not guarantee the accuracy, validity, timeliness, or completeness of the information. Please filter carefully. If you believe that this article infringes, please contact the administrator. We are not responsible for any consequences of the information and services on this website.
Note: This compound is only used for laboratory research purposes. The US authorities have not evaluated these claims. Before use, please consult your doctor and learn about available research. This product is not intended for the diagnosis, treatment, cure, or prevention of any disease.
Hot Tags: dasiglucagon cas 1544300-84-6, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China