Product description
Colivelin is a synthetic neuroprotective peptide composed of Humanin (a natural mitochondrial peptide) and ADNF (activity-dependent neurotrophic factor), possessing strong brain penetration and long-lasting neuroprotective activity.
Mechanism of Action
Colivelin exerts its effects through a dual signaling pathway:
Activation of the STAT3 pathway: Inhibits neuronal apoptosis and promotes cell survival.
Enhancing synaptic plasticity: Strengthens interneuronal connections and improves learning and memory.
Antioxidant and anti-inflammatory effects: Scavenges free radicals, reduces inflammation, and protects mitochondrial function.
Inhibition of Aβ deposition: Blocks β-amyloid protein aggregation and reduces neurotoxicity.
Core Efficacy
Neuroprotection: Protects neurons from Aβ, oxidative stress, and ischemic damage even at extremely low concentrations (100 fM).
Cognitive Enhancement: Significantly improves spatial memory and learning ability in Alzheimer's disease models.
Anti-apoptosis: Effectively inhibits alcohol-, ischemia-, and toxin-induced neuronal death.
Repair and Regeneration: Promotes axonal growth, enhances neuronal survival, and aids in functional recovery after brain injury.
COA
| Tests | Specifications | Results |
| Appearance (surface and properties) | White or off-white powder, free of visible foreign matter | Meets regulations |
| Purity (HPLC) | 98.50% | ≥98.0% |
| Moisture (Karl Fischer method) | 4.20% | ≤6.0% |
| Acetate content | 7.80% | ≤12.0% |
| Amino acid composition analysis | Consistent with theoretical sequence | Meets theoretical composition |
| Solubility (water solubility) | Clear and transparent, no precipitation | Soluble in water |
| Microbial limits (total bacterial count) | <100 CFU/g | ≤1000 CFU/g |
| Conclusion | Conform with enterprise specification | |
Click email：sales4@faithfulbio.com Or WhatsApp：+86 17782784907
Molecular weight 2645.10000
Exact mass 2643.53000
PSA 1043.77000
LogP 2.51360
InChIKey PTTAQOYOJJTWFD-IBAOLXMASA-N
Research Applications of Colivelin
Alzheimer's Disease: Reduces Aβ deposition and improves cognitive impairment.
Stroke/Cerebral Ischemia: Reduces infarct size and promotes neurological function recovery.
Amyotrophic Lateral Sclerosis (ALS): Protects motor neurons and slows disease progression.
Fetal Brain Injury: Prevents alcohol-induced neuronal apoptosis.
why choose us
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With our continuous efforts and good service, we sincerely hope to establish long-term cooperation and common development with customers and give us a chance. We believe that we will satisfy you with first-class quality, safe and fast delivery and enthusiastic after-sales service.
Our Factory
Package
Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Click email：sales4@faithfulbio.com Or WhatsApp：+86 17782784907
FAQ
01. What are the structural characteristics of Colivelin?
It consists of 26 amino acids, has a compact structure, good water solubility and stability, and can efficiently enter the brain to exert its effects.
02. How does Colivelin exert its neuroprotective effects?
Colivelin can maintain neuronal health by activating intracellular signaling pathways, inhibiting neuronal apoptosis, and reducing oxidative stress and inflammatory responses.
03. Where can I buy Colivelin?
You can contact the following email address: sales4@faithfulbio.com
Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.
Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.
Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.
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