Capixyl Peptide CAS 827306-88-7

Acetyl tetrapeptide-3 Introduction

Xi'an Faithful BioTech Co., Ltd. is an export-oriented biotechnology and chemical trading company headquartered in Xi'an, Shaanxi Province, China. Founded in 2018, the company focuses on providing pharmaceutical intermediates, plant extracts, food additives, and feed ingredients to the global B2B market.  

As a lean, professional supplier, we implement rigorous quality control to ensure batch stability and compliance. With an experienced international sales team, we offer highly competitive prices, reliable delivery times, and one-stop export services.

Our products are widely supplied to the pharmaceutical, health supplement, cosmetic, and feed industries in Europe, North America, Southeast Asia, and the Middle East.   

Acetyl Tetrapeptide-3 is an artificially synthesized biomimetic peptide composed of four amino acid sequences. It is a commonly used functional raw material in the beauty industry. Its CAS number is 827306-88-7; molecular formula is C22H39N9O5; molecular weight is 509.6; EINECS number is 1308068-626-2.
Capixyl Peptide is mostly prepared in batches using the solid-phase peptide synthesis process. It is applicable for both laboratory small-scale trials and industrial mass production. The finished product is mostly in powder form, with a purity of generally 98%. After refinement, it can achieve near-total purity.
It can act on hair follicle cells, promoting the generation of type III, type VII collagen, and laminin and other matrix proteins, strengthening the environment where hair roots attach, reducing hair strand shedding, and simultaneously enhancing hair density and assisting hair growth.
This ingredient is often compounded in hair growth and hair care essence, eyelash growth liquids, and eyebrow care products on the market. Many anti-aging skincare formulas also use it in combination, aiming to achieve the effect of repairing the skin base.

How safe is Acetyl Tetrapeptide-3?

Acetyl tetrapeptide-3 is a very mild biomimetic peptide-based active ingredient in the fields of hair care and skin care. It has high overall safety and is a highly recognized component in current high-end hair growth and anti-aging formulas.
Capixyl Peptide itself has extremely low irritation and its molecular structure is very close to the peptide structure of the human body. Under normal and compliant addition conditions, it will not irritate the scalp, cause sensitization, cause redness, or cause a stinging sensation. Even for sensitive scalps, fragile eye area eyelashes, and eyebrow skin, it can be safely adapted, and its mildness and adaptability are extremely strong.
From practical application feedback, its sensitization rate is very low. When used in large quantities on a daily basis, there is almost no situation of intolerance, and it will not damage the skin and scalp barrier. The ingredient is only a signaling substance for the skin to help regulate its own protein production. It has no dependence and will not become worse with repeated use. Long-term use will not cause tolerance problems.
At the same time, its formulation compatibility is very good. It can be stably combined with common plant care ingredients, moisturizing ingredients, and other peptide-based raw materials without causing ingredient conflicts or generating irritating by-products.
Acetyl tetrapeptide-3 itself has excellent stability. As long as it is protected from light, kept dry, and sealed for storage, it is not prone to deterioration or inactivation. When mixed into the finished hair care formula, it is safe and stable for use within the normal shelf life.
Overall, Acetyl tetrapeptide-3 belongs to a safe, low-risk, and widely adaptable efficacy raw material. It is a very reliable and preferred active ingredient in hair care and skin repair formulas.

What is the mechanism of action of Acetyl tetrapeptide-3?

The core mechanism by which Capixyl Peptide maintains hair health is to stimulate various structural proteins in the extracellular matrix around the hair follicles, thereby firmly fixing the position of the hair roots.
Acetyl tetrapeptide-3 can promote the production of basic proteins that support the hair follicles, such as type III collagen, type VII collagen, and laminin. These substances are crucial for maintaining the intact shape of the hair follicles and fixing the hair strands.
At the same time, it can also relieve scalp discomfort and reduce the secretion of factors like IL-8 that cause redness and discomfort, creating a gentle and stable scalp environment for hair growth.
If used in combination with other active ingredients for skin care and hair care, they can mutually enhance each other's effects, accelerating the proliferation and movement of dermal papilla cells; upregulating signaling substances like VEGF and β-catenin that are beneficial for hair development, and reducing factors like TGF-β1 that can delay hair growth. Through multiple action pathways, they jointly care for the hair strands and enhance density.

MF of Acetyl tetrapeptide-3

CAS	827306-88-7
Molecular formula	C22H39N9O5
Molecular weight	509.6
EINECS	1308068-626-2
Boiling point	1075.4±65.0 °C
Density	1.250±0.06 g/cm3

Specification

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FAQ: 

Q1:Will Acetyl Tetrapeptide-3 cause the scalp to produce more oil?
It has no effect on stimulating oil secretion. At the normal addition concentration, it will not aggravate the problem of excessive head oil and dandruff.
Q2:Which type of hair loss patients is Acetyl tetrapeptide-3 suitable for?
It is more suitable for diffuse hair loss caused by fragile hair follicle bases and insufficient nutrient matrix, as well as mild hair loss after childbirth.
Q3:How long will it take to see the hair care effect of Acetyl tetrapeptide-3?

The hair follicle metabolism cycle is relatively long. It takes 2 to 3 months of continuous use to notice a significant reduction in hair loss and an increase in new hair growth.

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