what is xep-018 peptide?
Xep-018 Peptide (CAS 936616-33-0) is a loose white to off white solid powder. Natural conus peptide mimics obtained from the venom of marine conus consols using biosimulation technology. It is mainly used as a neuromuscular conduction regulator, which can effectively block voltage-gated sodium ion channels (Nav1.4), thereby achieving muscle relaxation and instant wrinkle removal effects. Therefore, it is widely used in anti-aging skin care products, commonly used in essence, face cream and other formulations to smooth dynamic lines and improve skin smoothness. At the same time, it is also used as an ion channel tool drug in the field of scientific research.
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Product name |
xep-018 |
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CAS |
936616-33-0 |
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Molecular formula |
C92H139N35O28S6 | |
| EINECS | 606-757-9 | |
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Molecular weight |
2375.71 | |
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Appearance |
white powder |
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| Density | 1.71±0.1 g/cm3(Predicted) |
What are advantages of xep-018 peptide?
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xep-018 peptide is a highly folded peptide with strong penetration, high stability, and targeted relaxation effect on muscles. By blocking the electrical conduction of nerves and muscles, wrinkles can be instantly reduced, making the skin look younger and rejuvenated. |
Product Specification
| Items | Specifications |
Result |
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Appearance |
White powder |
conforms |
| Solubility | Soluble in H2O |
conforms |
| Counter Ion | Report | Acetic acid |
| Mass spectrum | 2375.7 ±1.0 | 2375.7 |
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Assay(By HPLC) |
95% min |
98.1% |
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How does xep-018 peptide achieve anti wrinkle effects?
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Research on the structural characteristics of conotoxin peptides, such as signal peptide sequences connected by disulfide bonds, has found that Xep-018 Peptide can block nerve signal transmission and inhibit muscle contraction by inhibiting sodium ion channels, calcium ion channels, and acetylcholine receptors, ultimately achieving the effect of reducing wrinkles |
What are the attack targets of other conotoxins besides xep-018 peptide?
five biologically active conotoxins have been identified. Each of the five conotoxins attacks a different target:
α-conotoxin inhibits nicotinic acetylcholine receptors at nerves and muscles.
δ-conotoxin inhibits fast inactivation of voltage-dependent sodium channels.
κ-conotoxin inhibits potassium channels.
μ-conotoxin inhibits voltage-dependent sodium channels in muscles.
ω-conotoxin inhibits N-type voltage-dependent calcium channels.Because N-type voltage-dependent calcium channels are related to algesia (sensitivity to pain) in the nervous system, ω-conotoxin has an analgesic effect Therefore, a synthetic version of ω-conotoxin M VII A has found application as an analgesic drug ziconotide (Prialt).
Company profile
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
FAQ
Q1:How Xep-018 works?
A1:It mainly targets the voltage-gated sodium channel Nav1.4, inhibiting muscle contraction by blocking the transmission of nerve signals, thereby relaxing overly tense muscles and achieving the effect of quickly smoothing wrinkles.
Q2:How to store the received goods?
A2:To ensure stability and activity, it is recommended to store at -20 ℃ to avoid repeated freeze-thaw cycles.
Q3:What is the recommended amount of additives in cosmetics?
A3:As an active ingredient, it is recommended to add a very low amount, usually between 0.001% and 0.01%.
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Note: The product is for research use only and is not intended for diagnosis, treatment, disease prevention, etc.
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