what is Biotinoyl tripeptide-1 hair loss?
Biotinoyl tripeptide-1 hair loss is a functional modified peptide formed by linking biotin and tripeptide Gly His Lys through amide bonds. A fine powder form ranging from white to off white, with a purity of over 98%. The CAS number is 299157-54-3, the molecular formula is C24H38N8O6S, and the molecular weight is approximately 566.67 g/mol. Mainly produced through artificial chemical synthesis. It can effectively stimulate the synthesis of collagen IV and laminin 5, helping to fix hair in hair follicles, prevent hair loss, and promote hair growth. Therefore, it is widely used in hair care cosmetics and scalp care products, as well as in some functional foods and scientific research fields.
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Product name |
Biotinoyl tripeptide-1 |
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CAS |
299157-54-3 |
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Molecular formula |
C24H38N8O6S | |
| EINECS | 207-048-3 | |
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Molecular weight |
566.67 | |
| Melting point | 1128.5±65.0 °C(Predicted) | |
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Appearance |
white powder |
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| Density | 1.321±0.06 g/cm3(Predicted) |
What is Key Benefits of Biotinoyl tripeptide-1 hair loss ?
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Reduced Hair Loss: By strengthening follicle anchoring, it significantly reduces hair shedding. Increased Hair Density: Research indicates it can lead to a greater density of hair on the scalp. Stronger Hair: The enhanced keratin production and follicle support result in thicker, more resilient hair. Biotinoyl tripeptide-1 hair loss also has following benefits:Anti aging and firming of the skin |
Product Specification
| Items | Specifications |
Result |
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Appearance |
White powder |
Conforms |
| Identification | Positive | Conforms |
| Loss on Drying |
1% MAX |
0.06% |
| Heavy metals | 10ppm MAX |
<10ppm |
| Purity | 98% MIN | 99.5% |
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What is the Mechanism of action of Biotinoyl tripeptide-1 hair loss?
- Strengthens Follicles
Biotinoyl tripeptide-1 stimulates the production of vital components like collagen IV and laminin 5. These proteins are crucial for reinforcing the connection between the hair follicle and the scalp, preventing premature shedding and enhancing hair anchoring.
- Promotes Hair Growth
The peptide extends the hair's growth (anagen) phase, allowing hair to grow longer and stronger. It also stimulates the synthesis of keratin, the primary protein in hair, contributing to a more robust hair shaft.
- Improves Follicle Health:
By enhancing the overall health and structure of hair follicles, biotinoyl tripeptide-1 creates a more conducive environment for hair growth and helps combat hair thinning.
- Enhances Scalp Microcirculation
The ingredient is thought to improve blood flow to the scalp, which delivers essential nutrients and oxygen to the hair follicles, further promoting hair regeneration.
- Reduces Inflammation
Biotinoyl tripeptide-1 possesses anti-inflammatory properties that help calm an irritated scalp, removing a potential barrier to healthy hair growth
How to synthesize Biotinoyl Tripeptide-1 hair loss?
The liquid-phase synthesis method of Biotinoyl Tripeptide-1 involves the field of peptide synthesis technology, including: using functionalized ionic liquid as a carrier, bonding Boc Lys OH through condensation reaction, then connecting with Trt His OH through dehydration condensation, and then cutting and removing the functionalized ionic liquid in alkaline environment to obtain His (Trt) - Lys (Boc) - OH; Then, biotin-N-hydroxysuccinimide ester is chemically linked to Glycine to obtain Biotin-Gly-OH, which is then dehydrated and deprotected to obtain Biotinoyl Tripeptide-1 hair loss.
Company profile
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
FAQ
Q1: What is the main mechanism of action of the product?
A1:By stimulating the dermal papilla layer cells of the scalp, the synthesis of collagen IV and laminin 5 is promoted, thereby strengthening the structure of hair follicles, firmly anchoring hair roots, and achieving the effect of preventing hair loss and promoting growth.
Q2:What is the water solubility of the product?
A2:Has good water solubility. The solubility in water is greater than 5mg/mL, making it convenient for formula application.
Q3:How should the product be stored?
A3:It needs to be sealed and stored away from light. Short term storage is recommended to be refrigerated at 2-8 ℃, while long-term storage is recommended to be placed in a -20 ℃ frozen environment.
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Note: The product is for research use only and is not intended for diagnosis, treatment, disease prevention, etc.
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