What is ATX-GD-59 Peptide?
Xi'an Faithful BioTech Co., Ltd. is situated in Xi'an, the birthplace of the ancient Silk Road. Leveraging the city's mature logistics network and abundant fine chemical industrial resources, our enterprise has grown into an integrated fine chemical provider that delivers products to global partners. ATX-GD-59 Peptide is composed of two peptide segments derived from the characteristic sequence of the human thyroid-stimulating hormone receptor (TSH receptor) in equal proportions. One segment replicates the dominant epitope of the innate immune system, while the other segment undergoes structural optimization by adding hydrophilic amino acids at both ends, significantly improving its water solubility. It is a white powder with a purity exceeding 98%. The core mechanism of this complex peptide revolves around the regulation of immune tolerance. It can efficiently bind to HLA-DR molecules on the surface of immature dendritic cells in lymph nodes, moderating the activation process of antigen-presenting cells, gently regulating the activity of corresponding lymphocytes, and balancing the body's immune response to thyroid-related receptors. Unlike materials that broadly act on the systemic immune system, its action is more targeted, regulating only specific immune signaling pathways without significantly affecting the overall immune environment.
Application of ATX-GD-59 Peptide
The overall application scenarios of ATX-GD-59 Peptide are focused on basic scientific research and mechanism exploration in the field of endocrinology and immunology. It can be used for the construction of Graves's immune imbalance animal models and the observation of immune response regulation. It is also suitable for basic experiments at the cellular and animal levels on thyroid-stimulating hormone receptor-related immune signaling pathways and epitope tolerance regulation logic. At the same time, it supports research on peptide bioactivity assessment and long-term observation of biological performance under standardized conditions. The data generated from related experiments can also be used to improve the theoretical research on thyroid-related autoimmune systems. At present, it is only open to various scientific research scenarios and is not open to daily human use.
COA
| Test Item | Specification | Test Result |
| Appearance | white powder | Complies |
| HPLC Purity | ≥98.0% | ≥98.0% |
| Peptide Content | ≥70.0% | Complies |
| Moisture Content | ≤8.0% | Complies |
| Acetate Content | 5.0%-12.0% | Complies |
| Conclusion | Conform with enterprise specification | |
Click email：sales4@faithfulbio.com Or WhatsApp：+86 17782784907
ATX-GD-59 Peptide is a mixed peptide material composed of two custom-synthesized peptides. It is odorless and free of visible impurities. Its water solubility has been optimized through molecular structure modification, resulting in rapid dissolution in neutral buffered aqueous solutions. The dissolved solution is clear and free of turbidity or precipitate, making it suitable for various cell culture buffer systems. Strict storage conditions are required. It must be stored long-term in a light-proof, vacuum-sealed environment at -20°C. Repeated thawing at room temperature will cause molecular degradation and decrease in biological activity. Short-term room temperature transport requires a cryogenic protection carrier. After opening, it is recommended to aliquot and seal once for cryogenic storage.
Mechanism of action of ATX-GD-59 Peptide
Targeted binding to specific cell surface molecules: The peptide component specifically binds to HLA-DR molecules corresponding to immature dendritic cells in lymph nodes, enabling gentle antigen signal transduction.
Regulation of specific lymphocyte activity: Through antigen signal transduction, it weakens the activity of lymphocytes that abnormally respond to thyroid receptors, reducing abnormal immune signal output.
Reconstruction of local immune balance: It induces the generation of regulatory immune cells, refining the body's response logic to thyroid receptor antigens and restoring native tolerance.
Highly targeted action: It only regulates local immune signaling pathways related to thyroid receptors, without significantly interfering with the body's overall immune cycle, ensuring precise and controllable impact.
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Our Factory
Package
Shipping Methods
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS |
Suitable for under 50kg. International door to door express |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order |
|
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
FAQ
01. What environmental conditions can damage the molecular structure of ATX-GD-59 Peptide?
High temperatures, strong acids, and strong alkalinities can cause peptide chain breakage, resulting in the material losing its original biorecognition properties.
02. How well does ATX-GD-59 Peptide exhibit biological tolerance?
In various standardized observations, overall adaptability is mild, with very few systemic homeostatic fluctuations; only mild, self-resolving localized surface somatosensory feedback occurs.
03. Does ATX-GD-59 Peptide significantly disrupt the overall immune environment?
No, ATX-GD-59 Peptide only specifically regulates the immune balance corresponding to a single antigen and does not have a broad-spectrum effect on interfering with the systemic immune system.
Click email：Sales4@Faithfulbio.Com Or WhatsApp：+86 17782784907
Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.
Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.
Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.
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