Acetyl Tetrapeptide-11 Powder CAS 928006-88-6

Acetyl Tetrapeptide-11 Powder is a bioactive peptide composed of four amino acids (proline-proline-tyrosine-leucine) connected by peptide bonds, and has acetyl modification at the N-terminal. Its CAS number is 928006-88-6, its molecular formula is CHNO, its molecular weight is 530.61, its appearance is white powder, and its purity is usually ≥98%. This component belongs to acetyl peptides, which has attracted much attention in the field of skin care in recent years. It is mainly used for anti-wrinkle and anti-aging and improving skin quality.

What is the mechanism of action of Acetyl Tetrapeptide-11 Powder?

Acetyl Tetrapeptide-11 Powder has synergistic anti-aging effect through multiple mechanisms. At the collagen level, this component can directly stimulate skin fibroblasts, and significantly improve the synthesis of collagen I (the main structural protein of skin) and collagen XVII (the key component of basement membrane). The decrease of collagen XVII is directly related to skin aging and the decline of barrier function. Supplementing this component can enhance the tightness of epidermis-dermis connection and improve skin elasticity and compactness. In terms of photoprotection, Acetyltetrapeptide 11 powder promotes the production of photosensitive proteins (such as photolyase), which can effectively neutralize DNA damage induced by ultraviolet rays (such as thymine dimer) and reduce the risk of photoaging. At the same time, it can promote proteoglycan -1(Versican) to maintain skin hydration by binding hyaluronic acid, form a physical water barrier, and reduce transdermal water loss. At the level of signal pathway regulation, this component activates TGF-β pathway and inhibits matrix metalloproteinase (MMP) from degrading collagen, thus delaying the collapse of dermal structure and preventing wrinkles. In addition, acetyl tetrapeptide -11 can also promote the differentiation and maturation of keratinocytes, repair the skin barrier function and enhance the skin's resistance to external stimuli. Clinical data show that after 28 days of continuous use, the skin elasticity increases by 22%, the wrinkle depth decreases by 18.7%, and the dynamic wrinkles such as crow's feet and decree lines are significantly improved. At the same time, the skin's transdermal water loss is significantly reduced, the water-locking ability is enhanced, and sensitive symptoms such as redness and itching are significantly alleviated.

What are the effects and side effects of on-site application of Acetyltetrapeptide 11 peptide Powder ?

Acetyl tetrapeptide -11 shows remarkable anti-wrinkle and anti-aging effect in clinical application. Clinical data show that after 28 days of continuous use, the skin elasticity can be increased by 22%, and the wrinkle depth can be reduced by 18.7%, especially for dynamic lines such as crow's feet and decree lines. Its mechanism of action is mainly realized through three pathways: promoting the synthesis of collagen I and collagen XVII, and enhancing the tight junction between epidermis and dermis; Activating photoprotein production and neutralizing DNA damage induced by ultraviolet rays; Promote the synthesis of proteoglycan -1 and improve the skin's water-locking ability by 30%. In terms of safety, Acetyl Tetrapeptide-11 Powder is a mild and non-irritating component, which has low irritation to the skin and is relatively safe and reliable to use. However, attention should be paid to individual differences. People with sensitive skin or allergic to amino acids should use it with caution. It is recommended to have an after-ear test before using it. If allergic reactions (such as redness, itching, rash, etc.) occur, stop using it immediately. The recommended dosage of this component is 0.01%-0.2%, which needs to be matched with penetration enhancer to improve the transdermal rate, and the pH adaptation range is 4.0-7.5 to avoid direct compatibility with strong oxidizing components. Storage conditions suggest freeze-drying at -20℃ and dark storage to maintain stability. At present, it has passed the examination of China's Catalogue of Used Cosmetic Raw Materials (2021 Edition) and Japan's Table of Cosmetic Basic Components, ensuring the compliance of this product in the two markets.

What are the advantages of Acetyl Tetrapeplide-11 powder compared with other anti-aging components (such as retinol and peptide complex)?

Compared with retinol and peptide complexes, Ac-PPYL-OH has unique advantages in mildness, targeting and synergy. Compared with retinol, acetyl tetrapeptide -11 powder has very low irritation, no need to establish a tolerance period, is suitable for sensitive muscles and daytime use, and has no photosensitivity and can be protected all day; However, retinol needs to be used away from light, which is easy to cause intolerance reactions such as peeling and redness. Compared with the traditional peptide complexes, Ac-PPYL has a more precise mechanism of action. It can improve wrinkles from the structural level by promoting the synthesis of collagen I and XVII, enhancing the tightness of epidermal-dermal connection, and at the same time, it has the function of light protection and can neutralize ultraviolet damage, which most peptides do not have. In addition, Acetyltetrapeptide 11 has a good synergistic effect with retinol and other peptide components, and can be used in combination to enhance the anti-aging effect, realize multi-channel anti-aging, and has good stability, wide pH adaptation range and strong formula compatibility.

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Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide 99% Purity Acetyl Tetrapeptide-11 Powder etc. at a more favorable price. If you are interested, please leave a message.
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FAQ:

Q1: Where do you ship from?
We ship from multiple logistics hubs, primarily Hong Kong, Shenzhen, and Shanghai, allowing us to offer flexible and efficient delivery options. All products are carefully and securely packed to ensure safe transit.
Q2: How are products packaged for shipping?
We use discreet, unmarked outer packaging. Internally, products are double-sealed in sterile, transparent barrier bags to maintain integrity and hygiene. This method, refined through extensive experience, ensures both security and discretion throughout the shipping process.
Q3: How is customs clearance handled?
By Express Delivery:​ Generally, no action is required by the recipient. Should any customs issues arise, our experienced and professional team will provide support to facilitate clearance.
By Air or Sea Freight:​ We work closely with the recipient, supplying all necessary documentation and information to assist in the customs clearance process.

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