99% Purity Peptide Retatrutide Powder CAS 2381089-83-2
Product Name:Retatrutide
Synonym:LY3437943;GIPR/GLP-1R;Retatrutide/LY3437943/GIPR/GLP-1R;Retaglutide;Retatrutide acetate;LY3437943Retatrutide;Retalutide
CAS NO.:2381089-83-2
EINECS NO.:200-001-8
Molecular Formula:/
Purity & Grade: 99%; Medicine grade
Character:White powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 1g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 5-10 days
Store & Shelf life: Cool & dry place; 24 months
Description
Product description
99% Purity Peptide Retatrutide Powder CAS 2381089-83-2 is a novel peptide product that is a triple agonist of glucose-dependent insulinotropic peptide (GIP), glucagon-like peptide-1 (GLP-1), and glucagon receptor, with a primary focus on research into the treatment of obesity and type 2 diabetes.
Common side effects include gastrointestinal symptoms such as nausea, vomiting, and diarrhea, similar to those of other GLP-1 products. These symptoms are common initially, but patients usually adapt over time.
Compared to similar products that act on only 1-2 receptors (such as Semaglutide, a GLP-1 receptor agonist, and Tirzepatide, a GLP-1/GIP dual receptor agonist), Retatrutide's triple-target synergistic effect offers a more comprehensive metabolic regulatory advantage:
GLP-1 receptor activation: Delays gastric emptying, inhibits central appetite, promotes glucose-dependent insulin secretion, and reduces blood glucose fluctuations.
GIP receptor activation: Enhances insulin sensitivity, reduces lipid accumulation in adipocytes, and helps improve insulin resistance.
Glucagon receptor activation: Promotes lipolysis (especially visceral fat), increases energy expenditure, and further enhances weight loss.
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COA
| Tests | Specifications | Results |
| Appearance | White or almost white fluffy powder | Conform |
| Solubility | Soluble in water | Conform |
| Water Content (Karl Fischer) | ≤ 8.0% | 4.60% |
| Sodium ion | ≤ 5.0% | 1.03% |
| Trifluoroacetic Acid | ≤ 0.5% | Not Detected |
| Peptide Purity (By HPLC) | ≥ 98.0% | 99.65% |
| Related Substance (By HPLC) |
Total Impurities(%) ≤ 2.0% | 0.97% |
| Largest Single Impurity(%) ≤ 1.0% | 0.38% | |
| Bacterial | ≤10EU/mg | Conform |
| Endotoxins | ||
| Total Aerobic Microbial Count | ≤10² cfu/g | Conform |
| Total Yeast And Mold Count | ≤10² cfu/g | Conform |
| Residual Solvents | Acetonitrile:NMT 410ppm | 86ppm |
| Dichloromethane:NMT 600ppm | Not Detected | |
| DMF:NMT 880ppm | Not Detected | |
| Conclusion | Conform with enterprise specification | |
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Appearance and properties: White powder
Purity (HPLC): ≥ 98.0%
Acetate content: ≤ 12.0%
Water content: ≤ 8.0%
Peptide content: ≥ 80.0%
Endotoxin: ≤ 50 EU/mg
Amino acid composition analysis: ≤ ± 10%
Preparation Method of 99% Purity Peptide Retatrutide Powder CAS 2381089-83-2
The sequence structure of Retatrutide is as follows: H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-αMeLeu-Leu-Asp-Lys-Lys(AEEA-γGlu-Eicosanedioic acid)-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Currently, there are few studies on the synthesis methods of Retatrutide. Gong Yulu et al. provided a method for synthesizing Retatrutide that has a short synthesis cycle, high HPLC purity of crude Retatrutide peptide, and high purity and purification yield of refined Retatrutide peptide. The synthesis method includes: preparation of peptide resin: sequentially coupling protected amino acids or protected polypeptide fragments onto a solid-phase support resin according to the sequence of Retatrutide to obtain peptide resin; preparation of crude peptide: cleaving the peptide resin using a lysis buffer to obtain crude peptide; and preparation of purified Retatrutide: purifying the crude peptide to obtain Retatrutide. The invented synthesis method uses protected polypeptide fragments for synthesis and has the following advantages: short time cycle, low preparation difficulty, low waste discharge, high overall yield, low cost, and is conducive to large-scale production.
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Our Factory
Package
Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
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7-15 days |
By Air |
Suitable for more than 50kg. |
|
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15-60 days |
By Sea |
Suitable for more than 500kg. |
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FAQ
01. Which is better, tirzepatide or 99% Purity Peptide Retatrutide Powder CAS 2381089-83-2?
02. Why is 99% Purity Peptide Retatrutide Powder CAS 2381089-83-2 better?
Retatrutide's unique molecular structure enables potent activation of GLP-1, GIP, and glucagon receptors, leading to significant weight reduction, improved glycemic control, and favorable metabolic outcomes.
03. Where can I buy 99% Purity Peptide Retatrutide Powder CAS 2381089-83-2?
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