Paroxetine Hydrochloride Powder is a phenylpyridine compound, which is a white or off white crystalline powder with no odor and a slightly bitter taste. Compared with other 5-HT reuptake inhibitors, pure paroxetine has the strongest ability to inhibit 5-HT. In clinical practice, it mainly treats various types of depression. This product has the advantages of good therapeutic effect and few adverse reactions.
| Molecular formula |
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|
|
Test Item |
Analysis Specification |
Result |
|
Appearance |
White to off-white crystal powder |
White to off-white crystal powder |
|
Identification A |
The infrared absorption spectrum should be consistent with the reference map |
Conform |
|
Identification B |
The retention time of the main peak of the solution should be consistent with the retention time of the main peak of the reference solution |
Conform |
|
Identification C |
Water by KF |
Conform |
|
Identification D |
Chloride reaction |
Conform |
|
Impurity D |
≤0.2% ≤0.2% |
Undetected Undetected |
|
Impurity G |
≤0.001% ≤0.001% |
Undetected Undetected |
|
Related substance1) |
Impurity A should not exceed 0.3% |
0.02% |
|
Related substance2) |
Each Identified impurity should not exceed 0.10% |
0.02% |
|
Related substance3) |
Total impurity should not exceed 0.5% |
0.08% |
|
Heavy metals |
≤0.002% |
≤0.002% |
|
Water |
2.2-2.7% |
2.4% |
|
Sulphate ash |
≤0.1% |
0.1% |
|
Content(No water) |
97.5-102.0% |
102.1% |
|
Residual solvent |
Methanol ≤0.3% |
0.001% |
|
Acetone |
≤0.5% |
0.001% |
|
Isopropyl-ketone |
≤0.5% |
0.004% |
|
Dichloromethane |
≤0.06% |
Undetected |
|
Toluene |
≤0.089% |
0.003% |
|
Conclusion |
This product conforms to the enterprise standard . |
|
What are the pharmacological effects of this product?
Paroxetine Hydrochloride Powder can be used to treat panic attacks, generalized anxiety disorder, social anxiety disorder, obsessive-compulsive disorder, insomnia, premenstrual syndrome, premature ejaculation, etc. Pure paroxetine hydrochloride exerts its therapeutic effect by inhibiting the reuptake of 5-HT in brain neurons, with stronger selectivity than tricyclic antidepressants (TCAs), fluoxetine, and sertraline, and rarely acts through other neurotransmitters. Clinical studies have found that paroxetine rew material can selectively inhibit the reuptake of serotonin (5-HT), increasing the availability of 5-HT for biological use in the synaptic cleft of nerve cells, thereby increasing 5-HTergic neurotransmission. It only weakly inhibits the reuptake of norepinephrine and dopamine.
This product does not interact with adrenaline alpha 1, alpha 2, or beta receptors, nor does it bind to dopamine D2 or histamine H1 receptors, nor does it inhibit monoamine oxidase. If paroxetine does not act on NE receptors in the brain, it indicates that the sedative effect of the product is minimal, the damage to cognitive processes or psychomotor function is also minimal, the affinity for cholinergic receptors and cardiovascular adverse reactions are less than TCAs, and short-term or long-term treatment has no specific changes in hematology, biochemistry, and urinary system.
Can this product cause diabetes?
Diabetes induced by PAROMOMYCINSULFATE powder is very rare, with a possibility of less than 1/10000, which occurs more than 6 months before the onset of treatment. The mechanism is complex, which may induce weight gain, decrease insulin sensitivity and induce insulin resistance, and block the cholinergic receptor or dopamine receptor in the brain. It is related to the disorder of blood glucose regulation. The principle of treatment is the same as type 2 diabetes. Blood sugar can be controlled by controlling diet and physical activity, Or get help from a physician.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Paroxetine Hydrochloride Powder etc. at a more favorable price. If you are interested, please leave a message.
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