Riluzole powder plays a neuroprotective role by inhibiting the release of neurotransmitters glutamic acid and aspartic acid in the brain, inhibiting the activity of excitatory amino acids, and stabilizing the inactivation of voltage-dependent sodium channels.
It is a benzothiazole derivative. In the 1950s, it was researched and developed as a central muscle relaxant. In 1995, the US FDA approved riluzole for the treatment of lateral sclerosis. Because of its extensive pharmacological effects, the research on riluzole has never stopped. At present, the research mainly focuses on physiological functions such as glutamate regulation, neuroprotection, antidepressant, anti-anxiety, epilepsy treatment, and analgesia. In recent years, with the deepening of the research on the pharmacological mechanism of riluzole, the research on its therapeutic effect has also been strengthened. Glutamate is the most important excitatory neurotransmitter in the central nervous system. The chemical structural formula of riluzole has a very special position in the maintenance of brain function. Excessive glutamic acid in intercellular space will produce toxicity to neurons and cause neuron degeneration and even death, thus causing various neurodegenerative diseases.
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| Real shot pictures of Riluzole | Riluzole structure diagram |
Product Application
1. Riluzole powder is used for the treatment of amyotrophic lateral sclerosis patients.
2. It can prolong the survival time and delay the occurrence of respiratory dysfunction.
3. its regulatory effect on glutamic acid
4. It has a protective effect on nerves.
5. Its influence on nerve discharge.
6. It can be anti-depressed.
7. It can resist anxiety.
8. It can resist epilepsy.
9. It can relieve pain.
Product Specification
Item | Specification | Results |
Appearance | the white or yellowish crystalline powder | complies |
Identification | by infrared spectrum | complies |
Melting point | 117.0℃-120℃ | 118.0℃-119.2℃ |
Moisture | ≤0.5% | 0.16% |
Related substances | ||
Total | ≤1.0% | 0.15% |
Individual | ≤0.5% | 0.08% |
Residue on ignition | 0.1% | 0.02% |
Heavy metal | ≤20ppm | complies |
Assay | ≥99.5% | 99.9% |
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Note: This compound should be used for research purposes only. These claims have not been evaluated by the Food and Drug Administration. Please consult your doctor and learn about available studies before using them. This product is not intended to diagnose, treat, cure or prevent any disease.
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