Product Introduction
Brivaracetam powder, a chemical analog of levetiracetam, is a piracetam derivative with anticonvulsant (anti-epileptic) properties. The product is used in combination with other anti-epileptic to improve some psychiatric problems. Brivaracetam powder is interchangeable with levetiracetam as follows: 50 mg brivaracetam is interchangeable with 1,000 mg levetiracetam, 100 mg brivaracetam is interchangeable with 2,000 mg levetiracetam, and 200 mg brivaracetam is interchangeable with 3,000 mg levetiracetam.
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| Brivaracetam powder picture | Brivaracetam powder MF |
Product Application
Brivaracetam powder is believed to work by binding to the ubiquitous synaptic vesicle glycoprotein 2A (SV2A), just like levetiracetam, but with 20-fold higher affinity. There is evidence that the piracetam class , including levetiracetam and Brivaracetam powder, can access the lumenal side of circulating synaptic vesicles during vesicle endocytosis. They may reduce the release of excitatory neurotransmitters and enhance synaptic depression during high-frequency activity sequences, such as events that occur during epileptic activity.
product key technologies
Brivaracetam powder exhibits linear pharmacokinetics over a wide dose range, is rapidly and completely absorbed after administration, has an elimination half-life of seven to eight hours, and is less than 20% plasma protein bound. It is extensively metabolized (>90%), primarily by hydrolysis of the acetamide group and secondarily by hydroxylation mediated by the liver enzyme CYP2C19.
The three major metabolites (hydroxy, acid, and hydroxy acid) are pharmacologically inactive. Brivaracetam powder is eliminated as urinary metabolites, with more than 95% of the radioactive test dose recovered in the urine within 72 hours, of which only 8.6% was unchanged brivaracetam.
Brivaracetam is a highly selective and affinity ligand for synaptic vesicle protein 2A, approved for the treatment of partial-onset seizures with or without secondary generalized seizures in adults and adolescents aged 16 years and older.
In a meta-analysis of 6 randomized, placebo-controlled, single- or double-blind trials, in which 1715 of 2399 participants were treated with brivaracetam, the rate of 50% responders (those with at least a 50% reduction in seizures from baseline) was approximately twice as high with brivaracetam as with placebo, and the rate of seizure freedom was nearly five times as high with brivaracetam.
Product Specification
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Test items |
Specifications |
Results |
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Appearance |
White or off-white crystalline powder |
White crystalline powder |
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Identification |
IR |
Complies |
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HPLC |
Complies |
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Loss on drying |
≤0.5% |
0.12% |
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Residue on ignition |
≤0.1% |
0.03% |
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Single impurity |
≤0.5% |
<0.12% |
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Assay |
≥98.0% |
99.80% |
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Heavy metal |
≤10ppm |
5ppm |
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Lead (Pb) |
≤3ppm |
1.5ppm |
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Cadmium (Cd) |
≤1ppm |
0.2ppm |
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Mercury (Hg) |
≤0.1ppm |
0.05ppm |
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Total impurity |
≤1.0% |
0.29% |
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Total bacteria |
≤1000cfu/g |
<1000cfu/g |
How To Obtain Samples of Brivaracetam powder?
Welcome to send an inquiry to sunny@faithfulbio.com at any time for a free sample if you need the API Brivaracetam powder.
The Best Brivaracetam powder Manufacturer And Supplier
Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.
We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.
Why Choose Faithfulbio Brivaracetam powder?
Faithfulbio specialize in Brivaracetam powder for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
kindly note: Use Brivaracetam powder for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.
Where To Buy Brivaracetam powder?
Just send an email to sunny@faithfulbio.com, or submit your requirement in the bottom form, we are of service at any time!
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