Vitamin A Powder CAS 68-26-8

all-trans-Retinol is a fat-soluble vitamin, which exists in animal food in the form of free aldehyde or ester, and is rich in fat, protein, milk and liver. Researchers have found that carrots, tomatoes and other vegetables do not contain natural vitamin A, but only the predecessor of vitamin A (provitamin A), which can be converted into vitamin A only after being eaten by animals through a series of biochemical changes. Retinol obtained in industrial production can be obtained from cod liver oil by molecular distillation and chromatography, but the method of obtaining pure vitamin A powder is chemical synthesis.

Should retinol be protected from light?

Retinol palmitate is a component of photosensitive substance in visual cells, which can maintain the integrity and health of epithelial tissue structure and promote the development and growth of the body. When lacking, it will lead to dry conjunctiva and cornea, inflammation, night blindness, and even blindness in severe cases. In addition, vitamin A will also damage respiratory epithelium and easily induce respiratory infection. If infants and young children lack for a long time, it will hinder the normal growth and development of the body, and may lead to reproductive function decline and hair loss for adults. When we encounter such a situation, we can supplement vitamin A powder in a proper amount, but it should be noted that vitamin A has a certain photosensitivity and cannot accept sunshine for a long time, especially after absorbing ultraviolet rays, it will cause irreversible irritating changes, resulting in the unavailability of products. However, the relevant research found that this product only has strong feedback to ultraviolet rays, so when storing and using it, just avoid it.

How to better supplement retinol?

vitamin A powder was first extracted from sturgeon liver by American scientists. However, due to the enhancement of marine protection awareness and the development of modern science and technology, the conventional way to obtain retinol at present is to obtain retinol directly from animal foods such as animal liver, nonfat milk and cod liver oil. Or plant food such as carrot, cauliflower, sweet potato, butter, cabbage, spinach, pumpkin, kale, cantaloupe, apricot, papaya, mango, pea, green pepper, persimmon, green, red and yellow fruits and vegetables. These plant foods are rich in carotenoids, which can be converted into retinol in liver (1 mg carotene =0.167 mg retinol). At present, the most popular skin care collocation is to use vitamin C in the morning for anti-oxidation and whitening, and vitamin A in the evening for anti-aging repair. Among them, vitamin C is a popular product, while vitamin A is less exposed. Retinol is vitamin A in a narrow sense, and vitamin A in a broad sense also includes retinol derivatives such as retinaldehyde, retinoic acid, retinol acetate and retinol palmitate.

Related research on retinol as skin conditioner in cosmetics

all-trans-Retinol has a long history in treating skin roughness and keratinization, and in recent years it has been favored by consumers as an effective anti-aging component of skin.
1. Improve skin aging: Retinol can increase the thickness of epidermis, promote the synthesis of type I collagen, GAG glycosaminoglycan, fibronectin and elastin, regulate the homeostasis of extracellular matrix in dermis, enrich the deposition of extracellular matrix in skin, and promote the proliferation of endothelial cells, making skin look fuller and more elastic.
2. Improve wrinkles: 0.075% and above concentration of retinol can improve fine lines.
3. Adjust skin color: improve pigmentation.

All the above effects have been confirmed by human efficacy evaluation tests, and the specific use effect varies from person to person. However, it should be noted that the special physical and chemical properties of retinol limit its application: it is easy to be inactivated under the conditions of light, heat and oxygen, with small molecular weight and high permeability, and improper use will lead to irritating problems such as skin redness, swelling and heat pain. vitamin A powder derivatives obtained by chemical structure modification can improve stability and reduce irritation to some extent, but the corresponding efficacy will be weakened to some extent. In addition, there are other methods to solve the application problems of retinol and its derivatives in cosmetics, such as liposome, microneedle, adding photoprotective agent and designing special packaging, but there are still problems such as complex preparation and low protection efficiency.

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