Isoflavone Powder CAS 574-12-9

Soy isoflavones are polyphenolic compounds that are secondary metabolites formed during the growth of soybeans. They mainly exist in a few plants such as soybeans and kudzu root in nature. High quality soy isoflavone powder is yellow or light yellow in color, with a slightly bitter odor and a slight astringency. It is soluble in water and resistant to heat and acid. In 1995, a certain media reported for the first time that Soybean Lsoflavones have a similar structure to mammalian estrogen and speculated that they possess various physiological activities of estrogen. Since then, the research progress of soy isoflavones has become a focus of attention in academia and even the world.

Why supplement soy isoflavones?

Soy isoflavones are a kind of polyphenols and secondary metabolites formed in the growth of soybean. Their molecular structure is very similar to estrogen secreted by human body, so they are called natural phytoestrogens. The research shows that soybean isoflavone has a special two-way regulation function. When human estrogen is insufficient, it plays a supplementary and activating role, and when estrogen is excessive, it plays an antagonistic role, preventing accumulation and excess, and keeping the estrogen in the user's body always balanced. In addition, regular use of high-purity Isoflavone powder can also improve the microcirculation of the body.

1, two-way regulation of estrogen

The estrogenic effect of soybean isoflavone is due to the similar chemical structure between soybean isoflavone and estrogen, so it can combine with estrogen receptor, play an estrogenic role and regulate endogenous estrogen. When the estrogen level in the body is low, soybean isoflavones show estrogen effect; However, when the estrogen level in the body is high, it shows anti-estrogen effect.

2. Antioxidant effect

Soybean isoflavone can inhibit the production of reactive oxygen species, reduce oxidative stress, reduce DNA oxidative damage and inhibit lipid peroxidation.

3. Other functions

Soybean isoflavones also have many other functions, such as improving metabolic syndrome, including preventing cardiovascular diseases, improving vasodilation function and reducing arterial stiffness, and reducing the total cholesterol level of patients with type 2 diabetes and postmenopausal women. In addition, soy isoflavones can also reduce the risk of endometrial cancer, ovarian cancer and lung cancer in non-smoking women.

What are the structures and functions of Isoflavone?

Soybean isoflavone is a flavonoid in soybean, and 486-66-8 Daidzein and 446-72-0 Genistein are the most common and have the highest content. In addition, it also contains Glycitein 40957-83-3; 5,7-Dihydrox -4'-methoxyisoflavone 491-80-5; Formononetin 485-72-3  and Puerarin 3681-99-0, etc.
Soybean isoflavone powder is similar to estrogen in structure (especially 17-β estradiol), which can cause weak estrogen effect or anti-estrogen effect according to the difference of endogenous estrogen and estrogen receptor. In addition, like other flavonoids, it has many functions such as antioxidation, inhibiting cancer cell proliferation, anti-inflammatory and antibacterial. Interestingly, the incidence of breast cancer and prostate cancer in Asians is lower than that in western countries, which may be related to the significant difference in the intake of isoflavones in Asian diets (15-47 mg/day) and western diets (0.15-1.7 mg/day).

What are the related research progress on isomers of flavonoids?

Isoflavones raw material are isomers of flavonoids, and the phenyl side chain on γ -pyridone ring is not connected to C2 position but to C3 position, which has certain physiological activities. Natural isoflavones are mainly distributed in angiosperms, and are also found in some plants of Leguminosae, Rosaceae and Iridaceae. Pueraria lobata, a leguminous plant, contains five isoflavone derivatives, namely Daidzein 486-66-8, Daidzin 552-66-9, Puerarin 3681-99-0, Puerarin 7-xyloside and Daidzein-4 ′, 7-diglucoside are generally regarded as precursors of hormones because their structures are similar to estrogen, which is different from flavonoids in that they react negatively to hydrochloric acid and magnesium powder.

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