D Panthenol Powder CAS 81-13-0

D Panthenol powder is a precursor of coenzyme A and an important vitamin drug. When it enters the human body, it can be converted into pantothenic acid and synthesized into coenzyme A, promoting the metabolism of proteins, fats, and sugars, protecting the mucous membrane and luster of the skin surface, and preventing the occurrence of diseases. Dexpanthenol raw powder with high purity is a colorless to slightly yellow transparent viscous liquid that may crystallize during long-term low-temperature storage. Has a slight special odor and is easily hygroscopic. Clinically, it is mainly used for the use of nutritional supplements or the synthesis of vitamin B5 intermediates.

Is D-panthenol an underestimated skincare ingredient? 

Vitamin B family is often found in the skin care products we usually use, among which provitamin B5 is one of them. However, due to the unstable nature of calcium pantothenate, it is easily affected by temperature and formula, thus reducing the biological application rate. Therefore, D Panthenol is also known as an underestimated skin care ingredient in vitamin B family. D-PANTHENOL is the precursor of calcium pantothenate pantothenic acid. It appears in a variety of cosmetic formulations precisely because it overcomes the above difficulties, and its properties are more stable and its permeability is better in clinical use, so it can penetrate into skin tissues more effectively and play a moisturizing role.
1. Excellent deep moisturizing performance: Panthenol has a small molecular weight, can effectively penetrate the stratum corneum and infiltrate the stratum corneum on the skin surface, has a powerful moisturizing effect, effectively improves the roughness of the skin, and makes the skin soft and not sticky;

2, stimulate the growth of epithelial cells, accelerate the healing time of epidermal wounds, and repair tissue wounds; It has therapeutic effects on eczema, sunburn, and infantile diaper rash. It is reported in literature that ointment containing 5% panthenol can accelerate the healing time of epidermal wounds by 30%.

3. Nursing effect on hair: Panthenol can penetrate into hair, permanently moisturize hair, improve hair luster, reduce hair bifurcation, prevent crispness and breakage, and repair damaged hair.

4. Nursing effect on nails: Panthenol can enhance hydration and improve nail flexibility.

What is the research on the deep effects of D Panthenol on the skin?

Panthenol can be divided into three types: mixed enantiomers (DL type), right-handed enantiomers (D-type), and left-handed enantiomers (L-type). Among them, only right-handed panthenol has high biological activity, so its application in the cosmetics industry is mainly based on D-panthenol. Research has found that 81-13-0 D-panthenol can be converted into pantothenic acid in the human body, and then coenzyme A is synthesized (coenzyme A is a complex molecule of pantothenic acid combined with adenosine 3-phosphate, pyrophosphate, and β - mercaptoethylamine). )Promote the metabolism of proteins, fats, and carbohydrates in the human body, protect the mucous membranes and hair luster on the skin surface, while a lack of D panthenol powder can lead to skin lesions and physiological disorders.
1: Anti inflammatory and sedative effects
D-panthenol has the ability to stimulate the growth of epithelial cells in the skin, thus it can have a calming and anti-inflammatory effect, promote metabolism, and accelerate wound healing. Therefore, cosmetics and skincare products targeting acne prone skin usually add the substance panthenol. When its anti-inflammatory and sedative effects are applied to acne prone skin, it can make the acne disappear faster, and the wound left after squeezing the acne will heal faster. Therefore, panthenol is a very strong ingredient for acne prone skin.
2: Moisturizing effect
The molecular diameter and molecular weight of D-panthenol are very small, and it can penetrate deep into the skin barrier, penetrate deep into the stratum corneum, and bring the moisture into the skin, thus playing a role in moisturizing and hydrating. Further research has shown that after using a product containing 2.5% D-panthenol for 7 days, when compared with the control group, it was found that the use of a product containing 2.5% D-panthenol significantly increased the moisture content of the human stratum corneum. So its moisturizing effect is also very powerful.
3: Regulating and improving effects
Research has shown that when Dexpanthenol combined with vitamin B6 is fully and completely absorbed by the skin, it can increase the hyaluronic acid content in the skin and enhance the metabolism of proteins, sugars, fats, and other substances in the human body. Thus playing a role in regulating the skin. Meanwhile, panthenol also has the effects of enhancing skin elasticity, improving rough skin, and relieving skin itching, making it very friendly to sensitive skin.

Is panthenol an important precursor for key cellular pathways?

As mentioned earlier, pantothenic acid is an important product of Dexpanthenol, which is mainly distributed in cells in a free state and converted into acetyl-CoA in epidermal cells. We know that Acetyl coenzyme-A is a key substance in human body to participate in body and metabolic reactions, in other words, it is an essential medium for maintaining life (maintaining and repairing all cells), so the storage of pantothenic acid in the body will become very critical, but pantothenic acid is unstable to heat, alkali and acid. Only by ingesting high-quality D-PANTHENOL raw material can we achieve our goal.

Knowledge supplement: What are the reaction processes related to body and metabolism that Acetyl coenzyme a participates in in human body?

1. Decomposition of fats, carbohydrates and protein to produce carbon dioxide, water and energy;

2. The synthesis of fatty acids and sheath lipids is used to realize the integrity and fluidity of stratum corneum lipid layer and cell membrane;

3. Cholesterol (sex and stress hormones) needed to synthesize steroids.

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