Pentoxifylline Powder CAS 6493-05-6

Pentoxifylline Introduction

Xi'an Faithful BioTech Co., Ltd. is an export-oriented biotechnology and chemical trading company headquartered in Xi'an, Shaanxi Province, China. Founded in 2018, the company focuses on providing pharmaceutical intermediates, plant extracts, food additives, and feed ingredients to the global B2B market.  

As a lean, professional supplier, we implement rigorous quality control to ensure batch stability and compliance. With an experienced international sales team, we offer highly competitive prices, reliable delivery times, and one-stop export services.

Our products are widely supplied to the pharmaceutical, health supplement, cosmetic, and feed industries in Europe, North America, Southeast Asia, and the Middle East. 

Pentoxifylline powder is a white powder with CAS number 6493-05-6; its molecular formula is C13H18N4O3; its molecular weight is 278.31; its EINECS number is 229-374-5; it is a semi-synthetic Xanthine derivative. The raw material is derived from the natural theobromine contained in cocoa beans, and it is prepared by grafting a ketone group structure. It was first introduced to the market in Europe in 1972.
This substance can reduce blood viscosity and enhance the deformability of red blood cells, thereby promoting the smooth flow of microcirculation. It is commonly used in clinical practice for intermittent claudication caused by chronic occlusive arterial vascular diseases; it can also address cerebral infarction-related cerebrovascular problems, or complications such as nerve damage caused by diabetes, foot ulcers, etc., and can also assist in regulating male infertility-related issues. Currently, there are many experiments exploring whether it can be combined with other products for auxiliary intervention in depression or improving conditions such as alcoholic hepatitis, secondary inflammation caused by COVID-19, etc.

What is the mechanism of action of Pentoxifylline?

The mechanism of action of Pentoxifylline powder mainly includes the following aspects: Firstly, it can increase the content of Cyclic AMP in red blood cells by inhibiting phosphodiesterase, thereby enhancing the deformability of red blood cells and enabling them to pass through narrow capillaries smoothly; at the same time, it can reduce blood viscosity and inhibit excessive aggregation of platelets, optimizing blood flow characteristics; moreover, this product can also reduce the generation of inflammatory factors such as tumor necrosis factor-α, exerting anti-inflammatory effects, and improving tissue microcirculation and oxygen supply. It is the combined action of these several mechanisms that enables it to effectively alleviate symptoms related to circulatory disorders.

What are the advantages of Pentoxifylline?

The most remarkable feature of Pentoxifylline powder is its unique multi-target action characteristics, with excellent overall performance and wide application scenarios. On one hand, it can reduce blood viscosity, enhance the deformability of red blood cells, and inhibit abnormal aggregation of platelets, effectively promoting microcirculation in the human body and improving the oxygen supply to tissues. This is the core principle behind its ability to address peripheral artery-related issues such as intermittent claudication. On the other hand, Pentoxifylline possesses outstanding anti-inflammatory and antioxidant capabilities, effectively reducing the production of various inflammatory factors such as TNF-α, thereby expanding its application value beyond the conventional field of vascular regulation.
In the area of neuro-psychological regulation, numerous randomized controlled trials and meta-analyses have shown that using it as an auxiliary regulatory method can significantly alleviate the discomfort symptoms of patients with moderate to severe depression, and also provide positive assistance in improving the cognitive state of patients with vascular dementia. In the field of tumor-assisted maintenance, the advantages of Pentoxifylline are also very prominent. Relevant clinical studies have confirmed that this substance can reduce the occurrence probability of peripheral nerve damage and oral mucosa damage caused by chemotherapy, delay the appearance of discomfort symptoms, and alleviate the pain after breast cancer surgery, accelerating the recovery speed of the wound.
In addition, Pentoxifylline can optimize the energy metabolism process of sperm, enhance sperm vitality and survival probability. In terms of safety, the overall performance of this substance is stable and reliable, and most mild gastrointestinal discomfort and other adverse reactions are mild and controllable. It metabolizes quickly in the human body, does not cause material accumulation problems, and has more guaranteed safety. At the same time, this substance has been included and recommended by multiple authoritative medical treatment guidelines at home and abroad, and has been included in the medical insurance category B list. It is a high-quality regulatory choice that combines good regulatory effects, safe use, and high cost-effectiveness.

MF of Pentoxifylline

CAS	6493-05-6
Molecular formula	C13H18N4O3
Molecular weight	278.31
EINECS	229-374-5
Melting point	98-100°C
Density	1.1713
Boiling point	421.13°C

Specification

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Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Pentoxifylline powder etc. at a more favorable price. If you are interested, please leave a message. 
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FAQ: 

Q1:What are the side effects of pentoxifylline?
Common symptoms include nausea, vomiting, abdominal distension, diarrhea, loss of appetite, and possibly dizziness and headache as well.
Q2: Why can Pentoxifylline improve blood circulation?
It doesn't work by forcibly expanding the blood vessels. Instead, it reduces the viscosity of the blood, restores the elasticity of the hardened red blood cells, and makes the blood "more smooth" on its own, allowing it to flow smoothly through the narrow microvessels.
Q3:What should be noted when using Pentoxifylline?

People with allergies and those who have experienced recent bleeding are strictly prohibited from using it. It is also necessary to be vigilant about the interactions between the products, and to monitor changes in bleeding and blood pressure.

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