Navitoclax CAS 923564-51-6
Product:Navitoclax;ABT-263;ABT263;CS-1871;CS-1967
CAS NO.:923564-51-6
Molecular formula:C47H55ClF3N5O6S3
Purity & Grade: 99% HPLC; Food grade
MOQ & Package: 100g; Package according to demand
Shipping: Safe and fast delivery
Store & Shelf life: Cool & dry place; 36 months
Lead Time: about 3 days
Warehouse: USA and Germany warehouse
Certificate:COA; HPLC; MSDS; TDS,etc.
Description
What is ABT-263?
Navitoclax is a small molecule Bcl-2 inhibitor that can induce cell apoptosis and bind to various anti apoptotic Bcl-2 family proteins.
Xi'an Faithful BioTech Co.,Ltd. always has been adhering to the enterprise spirit of "sincerity, professional service, win-win cooperation, create a better life together!" since its inception, keep continuous progress, independent innovation, is oriented to customer service and market demand, with a sincere heart and professional technology, provide customers the high-quality products and services.Our company sincerely provides you with ABT-263. Welcome to consult.
| Product name | Navitoclax |
| CAS | 923564-51-6 |
| Molecular formula | C47H55ClF3N5O6S3 |
| Molecular weight | 974.62 |
| EINECS Number | NA |
| melting point | 114-116°C |
| solubility | NA |
| Storage conditions | -20°C Freezer, Under Inert Atmosphere |
| Appearance | whitepowder |
| boiling point | NA |
| Density | 1.41±0.1 g/cm3 |
Product Specification
| Item | Specification | Results |
| Appearance | White powder; | Complies |
| Melting point | 114-116°C | Complies |
| IR Identification | Should comply with the reference spectrum | Comply with the reference spectrum |
| Individual Impurity | ≤0.2% | 0.10% |
| Total Impurity | ≤0.2% | 0.10% |
| Loss on Drying | ≤0.5% | 0.40% |
| Residual on ignition | ≤1.0% | 0.05% |
| Heavy metals | ≤10ppm | Complies |
| Assay | 98.0%~102.0% | 101.00% |
| Bacterial count | ≤1000cfu/g | ＜10cfu/g |
| Mould and Yeast Count | ≤100cfu/g | ＜10cfu/g |
| Escherichia coli | Not detected/g | Negative/g |
| Conclusion | Conform with enterprise specification | |
Where is ABT-263 used?
Navitoclax is commonly used in the following fields:
Disease treatment research: It induces apoptosis of bad cells by inhibiting the Bcl-2, Bcl xL, and Bcl-w protein families, showing a protective effect on bad cells overexpressing these proteins. It exhibits different cellular activities in various cell lines
Anti aging research: As an anti-aging cell scavenger, it can exert anti-aging effects by inducing apoptosis of aging cells.
Cognitive function research: In studies of vascular cognitive impairment, it has been shown to improve cognitive function in male mice, but no positive effects have been observed in female mice, and even delayed learning processes have been observed.
What are the effects of ABT-263?
Navitoclax has multiple biological activities and therapeutic potential, with specific effects as follows:
This product can induce synergistic reactions in most ovarian cancer cell lines and enhance caspase activation in SK-OV-3 and IGROV-1 cell lines.
This product exerts anti-aging effects by inducing apoptosis of senescent cells, and clearing senescent cells helps to slow down the progression of age-related degenerative diseases
Nano particle loaded Navitoclax can achieve targeted delivery and sustained release, effectively improving drug stability and therapeutic efficacy, and reducing systemic side effects.
How and where to buy ABT-263 wholesale?
Our products undergo experimental testing and are recognized by customers.
You can trust our order because we have a good record of selling legal educational drugs.
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
Please contact me, I am Tina, a sales2 from Faithful. I will provide you with professional service to ensure your shopping experience is enjoyable and secure.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
FAQ：
Q1:How do you keep reserve the products?
A1:Our shipping workers are very professional.They can pack various professional discreet package for hidding the products.
Q2:How is the quality I want to test?
A2:Before production and extraction, we will test all raw materials.Quality is our top priority. All products are strictly tested and confirmed by our QC and QA, approved by Third Party Lab in China.So you will be assured with Good Quality if you choose us. We welcome you test the product and hope to get your feedback.
Q3: How is the goods packed
A3:We usually send goods with disguise package outside and a double-layer sterile transparent bag inside.We have tried thousand of package methods, it looks serious and discreet.
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Note: This compound is only used for laboratory research purposes. The US authorities have not evaluated these claims. Before use, please consult your doctor and learn about available research. This product is not intended for the diagnosis, treatment, cure, or prevention of any disease.
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