Barbituric Acid Powder CAS 67-52-7
Product Name:Barbituric acid;Balonylurea acid;Babituric acid dihydrate;barbituric;Barbitursure;pyrimidinetriol
CAS NO.:67-52-7
Molecular formula:C4H4N2O3
Purity & Grade: 99% HPLC; Medicine grade
MOQ & Package: 100g; Package according to demand
Shipping: Safe and fast delivery
Store & Shelf life: Cool & dry place; 24 months
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse
Certificate:COA; HPLC; MSDS; TDS,etc.
Description
What is Barbituric acid?
Barbituric Acid is formed by condensation of malonic acid and urea, which has no anesthetic effect. However, after the C2 and C5 atoms are replaced by different genes, various barbiturates can be generated. For example, the oxygen in C2 is replaced by sulfur, that is, thiobarbital is generated.
Barbituric Acid powder is white crystalline powder. Melting point 245℃, dehydration and decomposition at 280℃. Soluble in hot water and ether, insoluble in cold water and alcohol. React with metals to form salts.

| Product name | Barbituric acid |
| CAS | 67-52-7 |
| Molecular formula | C4H4N2O3 |
| Molecular weight | 128.09 |
| EINECS Number | 200-658-0 |
| Storage condition | Store below +30°C. |
| Melting point | 248-252 °C (dec.) (lit.) |
| Solubility | The solubility in water was 11.45 g/L. |
| Appearance | White powder |
| Boiling point | 260℃ (decomposition) |
| Density | 1.6006 (rough estimate) |
What are the mechanisms of action of Barbituric acid?
Barbituric acid acts on different levels of the central nervous system and has nonspecific inhibitory effect. Its sedative and hypnotic mechanism may be related to its selective inhibition of thalamic reticular ascending activation system, thus blocking the conduction of excitement to cerebral cortex. Its anticonvulsant effect is achieved by inhibiting synaptic transmission in the central nervous system and increasing the threshold of electrical stimulation in the motor area of cerebral cortex.
Product Specification
| Item | Specification | Results |
| Appearance | White crystalline powder | Complies |
| Melting point | 253ºC | 253ºC |
| Loss on drying | 0.1% max | Complies |
| sulphated ash | 0.02% max | 0.02% max |
| Assay | 99.0% min | 99.40% |
| Conclusion | Confom with enterprise specification. | |
What is the role of Barbituric Acid?
Barbituric Acid powder is used as raw materials for organic synthesis, medicine, plastics and dye intermediates. It is an intermediate of drugs such as vitamin B12, and can also be used as polymerization catalyst and preparation of benzimidazolone organic pigment. It can also be used as a reagent for colorimetric determination of glyoxal and pentosan.
HTML5 atlas of Barbituric acid
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Preparation of Barbituric Acid:
Barbituric Acid was first obtained by Adolf von Baer through the reaction of dibromobarbituric acid and hydrogen cyanide, and later he published the reduction method of dibromobarbituric acid by sodium amalgam and hydrogen iodide. At present, the commonly used method is the condensation reaction of diethyl malonate and urea catalyzed by sodium ethoxide:
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Note: This compound should be used for research purposes only. These claims have not been evaluated by the Food and Drug Administration. Please consult your doctor and learn about available studies before using them. This product is not intended to diagnose, treat, cure, or prevent any disease.
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