5-Fluorouracil Powder CAS 51-21-8

5-Fluorouracil powder is white or white-like crystalline powder. It is a pyrimidine antimetabolite, which is a commonly used chemotherapy drug in clinic at present. It has effects on all stages of proliferation, can prevent the formation of thymine, inhibit DNA biosynthesis, and thus inhibit the growth of cancer cells. In addition,pure 5 Fluorouracil can also be used to study rice and wheat ear differentiation, genetic metabolism determination, plant growth and development research and so on.

What is the anticancer mechanism of 5-FU?

5-Flouracyl( shorter form ：5-FU)is a thymidylate synthase inhibitor, and also belongs to metabolic drugs. It is usually used as a chemotherapy drug for gastric cancer, colon cancer, liver cancer, pancreatic cancer, esophageal cancer and other diseases. The anti-cancer mechanism of 5-FU is to inhibit nucleotide synthetase and interfere with the synthesis of cellular deoxyribonucleic acid, thus leading to the death of tumor cells.

1.5-FU is a fluoropyrimidine drug, which is transformed into the active metabolite 5- fluoro -2'- deoxyuridine monophosphate (FdUMP) in vivo. FdUMP forms a covalent complex with thymidylate synthase, which blocks the reaction catalyzed by dihydrofolate reductase, thus inhibiting the synthesis of dTMP (deoxythymidylate). This process directly affects DNA synthesis and cell proliferation.

2.5-FU can also be metabolized into 5-FUTP and incorporated into RNA. This will interfere with the normal function of RNA, affect the synthesis of protein, and inhibit the growth and division of cancer cells.

3. In some cases, 5-FU can be further metabolized into 5-FdUTP. When it is incorporated into DNA, it will cause DNA strand breakage, which will lead to the initiation of DNA repair mechanism and apoptosis. 5-FU not only inhibits the synthesis of DNA and RNA, but also induces DNA damage to exert its anticancer effect.

Based on the above aspects, 5-Fluorouracil powder interferes with the growth and division of cancer cells through multiple channels and levels, and it is an efficient and broad-spectrum chemotherapy product choice.

Why can fluorouracil ointment be used for skin diseases?

Fluorouracil ointment was originally an antiviral ointment, and its medicinal components can be converted into 50-91-9 Floxuridine in vivo, which can inhibit virus replication and exert antiviral effect. Its clinical application effect is mainly reflected in antivirus and promoting the regression of skin lesions.
1. Antivirus: Fluorouracil ointment can interfere with the DNA synthesis of the virus, thus inhibiting the replication and proliferation of the virus, which has an excellent therapeutic effect on skin diseases caused by the virus, such as verruca plana.
2. Promote the regression of skin lesions: By inhibiting virus replication, fluorouracil ointment helps to reduce the skin inflammatory reaction caused by virus infection, thus promoting the regression of skin lesions. After clinical use of fluorouracil ointment, patients may feel itchy skin, pain and other symptoms have been alleviated.
But after all, it is only a kind of external medicine, and its therapeutic effect is limited. If there are skin diseases, it is necessary to follow the doctor's advice and cooperate with other methods and drugs for comprehensive treatment.

A variety of shipping methods for you to choose

Our strengths:

Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide 5-Fluorouracil powder etc. at a more favorable price. If you are interested, please leave a message.

We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.

Disclaimer: The information published on this website comes from the internet, which does not mean that this website agrees with its views or confirms the authenticity of the content. Please pay attention to distinguish it. In addition, the products provided by our company are only used for scientific research. We are not responsible for the consequences of any improper use.

If you are interested in our products, or have critical suggestions on our articles or are not completely satisfied with the products received, please contact us by Email ：sales6@faithfulbio.com   . Our team is committed to ensuring the complete satisfaction of customers.

Hot Tags: 5-fluorouracil powder cas 51-21-8, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China