Xi'an Faithful BioTech Co., Ltd. is an export-oriented biotechnology and chemical trading company headquartered in Xi'an, Shaanxi Province, China. Founded in 2018, the company focuses on providing pharmaceutical intermediates, plant extracts, food additives, and feed ingredients to the global B2B market.
As a lean, professional supplier, we implement rigorous quality control to ensure batch stability and compliance. With an experienced international sales team, we offer highly competitive prices, reliable delivery times, and one-stop export services.
Our products are widely supplied to the pharmaceutical, health supplement, cosmetic, and feed industries in Europe, North America, Southeast Asia, and the Middle East.
Introduction to Sunitinib Malate
Sunitinib malate white powder appears as an orange powder (CAS: 341031-54-7; molecular formula: C26H33FN4O7; molecular weight: 532.57; EINECS: 638-825-9). It is a novel oral multi-target anti-tumor agent-specifically a multi-target kinase inhibitor-successfully developed by Pfizer. Offering dual anti-tumor activity, it is the only therapeutic compound capable of extending the survival of patients with advanced renal cell carcinoma beyond the two-year mark, playing a pivotal role in the treatment of renal cell carcinoma and gastrointestinal stromal tumors. Launched in the United States in February 2006, it was the first cancer drug approved by the FDA for the treatment of two distinct diseases.
| Molecular formula |
| |
| Item | Specification | Results |
| Appearance | White or yellowish powder | Conform |
| Identification | The IR absorption spectrum of sample must exhibit maxima at the same wavelength as the of reference standard. The retention time of major peak in test solution obtained in the test of Related substances by HPLC should correspond to that of the system suitability solution | Conform |
| Optical rotation | -0.05~+0.05° | 0.00° |
| Appearance of solution | Comply with the standard | Conforms |
| Sulphated ash | <0.1% | 0.05% |
| 2-Pro | <0.7% | Conform |
| Heavy metals | <10ppm | Conform |
| Individual impurity | <0.3% | 0.09% |
| <0.1 Impurity count | <2% | Conform |
| Assay | 98.5~100.5% | 99.64% |
| Total Plate Count | ≤ 1000cfu/g | 28.31 cfu/g |
| Total Yeast & Mold | ≤ 100cfu/g | 0.25 cfu/g |
| E.Coli | ≤ 1cfu/g | Negative |
| Salmonella | ≤ 1cfu/g | Negative |
| Conclusion： | Conform with enterprise specification . |
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Pharmacological action of Sunitinib Malate
Sunitinib malate white powder is a novel targeted therapy capable of selectively targeting multiple receptor tyrosine kinases. It combines an anti-angiogenic mechanism-blocking the blood supply to tumor cells-with an anti-tumor mechanism that directly attacks the tumor cells themselves. Sunitinib Malate works by cutting off the supply of blood and nutrients required for tumor cell growth. Clinical trials have demonstrated that the drug slows the progression of gastrointestinal stromal tumors (GIST) and reduces the size of renal cell tumors. Its indications include: 1. gastrointestinal stromal tumors (GIST) in patients who have failed or are intolerant to prior therapies; 2. unresectable advanced renal cell carcinoma; and 3. the treatment of advanced endocrine tumors (such as pancreatic endocrine tumors). Its introduction marks the dawn of a new era in targeted therapy; the drug not only directly attacks tumors but also avoids the toxic side effects associated with traditional chemotherapy agents.
How to use sunitinib malate?
Sunitinib malate is usually taken in capsules and can be taken with food. For the treatment of gastrointestinal stromal tumor (GIST) or renal cell carcinoma (RCC), sunitinib is usually taken once a day for 4 weeks (28 days), then rest for 2 weeks before starting the next dosing cycle, and repeat every 6 weeks for 9 weeks as recommended by your doctor. Sunitinib malate white powder is usually taken once a day for the treatment of pancreatic neuroendocrine tumors (PNET). Take sunitinib at about the same time every day. Before use, please carefully follow the instructions on the prescription note and ask your doctor or pharmacist to explain any part you don't understand. If your product is a whole capsule, please swallow it without splitting, chewing, or crushing. Don't open the capsule. It's very dangerous.
Is Sunitinib Malate a chemotherapy product?
Traditional chemotherapy agents work by interfering with cell division (mitosis) and affecting cellular DNA or RNA. While Sunitinib Malate is also used to treat certain types of cancer, it is classified as a targeted therapy compound rather than a traditional chemotherapy agent. Sunitinib Malate functions by inhibiting receptors found on the surface of certain cells-specifically, receptor tyrosine kinases (RTKs). These receptors facilitate intercellular communication and regulate various biological functions, such as cell growth, motility, differentiation, and metabolism. Research indicates that the activation of certain RTKs is linked to tumor growth, angiogenesis (the formation of new blood vessels from existing ones), and the progression of cancer metastasis. By inhibiting the activity of multiple kinases, Sunitinib Malate suppresses tumor growth and spread. In summary, Sunitinib Malate is a multi-kinase inhibitor, also referred to as a VEGF/VEGFR inhibitor.
A variety of shipping methods for you to choose
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS | Suitable for under 50kg. International door to door express | We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order | |
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Sunitinib Malate White Powder etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.
FAQ:
Q1:What is the solubility of Sunitinib Malate?
The product is soluble in organic solvents and has a certain degree of solubility in water.
Q2: What are the primary clinical applications of Sunitinib Malate?
It is primarily used in research on the regulation of cell proliferation; it acts on multiple kinase targets to inhibit abnormal cell proliferation and angiogenesis.
Q3:What are the side effects of Sunitinib Malate?
During the experiment, symptoms such as fatigue, reduced appetite, and gastrointestinal discomfort may be observed; in some instances, changes in skin color or fluctuations in blood pressure may also occur, with individual variations in the associated reactions.
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