The white to almost white Irbesartan powder is a long-term antihypertensive product, and also a first-line product for hypertension treatment. In addition to treating hypertension, it has a good effect on Parkinson's disease, diabetes nephropathy and other diseases. However, if excessive use of this product can lead to hypotension, tachycardia, or bradycardia, emetic, gastric lavage, and supportive therapy should be used.
| Molecular formula |
|
|
|
Items |
Standard |
Result |
|
Character |
White to off white crystalline powder, slightly soluble in alcohol and in methylene chloride, practically insoluble in water |
Conforms |
|
Identification |
A) IR spectrum is in accordance with the spectrum obtained with Irbesartan RS B) The retention time of the major peak in the chromatogram of the assay corresponds to Irbesartan RS. |
Conforms |
|
Water |
0.5% max |
0.2% |
|
Heavy metals |
0.002% max |
＜0.002% |
|
Residue on ignition |
0.1% max |
＜0.1% |
|
Related substances(HPLC) USP Impurity A Any unidentified impurity Total impurity |
0.2% max 0.1% max 0.5% max |
N.D 0.06% 0.06% |
|
Organic volatile impurities |
Meets the requirements of USP |
Conforms |
|
Residual azide |
10ppm max |
N.D |
|
Assay |
98.0~102.0%(calculated on anhydrous basis) |
100.7% |
|
Conclusion |
Complies with USP35 requirement for irbesartan |
|
Is irbesartan a safe product?
98% Irbesartan powder is a widely used angiotensin II receptor antagonist (ARB antihypertensive drug) that selectively blocks the binding of angiotensin II to AT1 receptors, thereby achieving the goal of vasodilation and lowering blood pressure. With its excellent antihypertensive effect and good tolerability, it has been safely used in clinical practice for more than 20 years and is one of the preferred drugs for many hypertensive patients.
In 2018, there was a global discussion on the toxic impurities in products, with some formulations of irbesartan being found to contain carcinogens, which sparked widespread public concerns about its safety.Especially when it causes panic among patients in the department, it puts a lot of pressure on the relevant medical departments.
Director Wang of a tertiary hospital in Beijing, a senior expert who has been engaged in the treatment of cardiovascular diseases for more than 30 years, pointed out that this issue needs to be viewed rationally. Detecting carcinogen does not necessarily mean that taking these drugs will cause cancer. The key lies in the impurity content and exposure time.
How to use irbesartan correctly?
In clinical practice, doctors have found that many patients have misconceptions about antihypertensive drugs. Some people are worried that frequent use of Irbesartan will lead to addiction, so they often stop using or change the usage without authorization; Some people have good blood pressure but are unwilling to start medication treatment. These misconceptions often lead to poor blood pressure control and increased risk of complications.
It is worth noting that if hypertension itself is not effectively controlled, the health hazards it causes far outweigh the potential risks that drugs may bring. A study tracking 100000 hypertensive patients for over 5 years showed that standardized use of antihypertensive drugs can reduce the risk of cardiovascular and cerebrovascular events by more than 40%. This data fully demonstrates the importance of antihypertensive drug treatment.
In addition, we need to understand that medication treatment is only a part of hypertension management, and it is more important to establish a healthy lifestyle. A retired teacher patient once maintained stable blood pressure from 170/100mmHg to 130/80mmHg for over 3 years by adhering to a daily brisk walk of 5000 steps, a salt restricted diet, and standardized medication.
If you are using pure AVAPRO or other antihypertensive drugs, it is recommended to undergo regular health check ups and maintain good doctor-patient communication. For any questions during the medication process, you can promptly consult the attending physician for professional advice. After all, scientific treatment is the correct way to control hypertension.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
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Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Irbesartan powder etc. at a more favorable price. If you are interested, please leave a message.
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