Tinidazole Powder CAS 19387-91-8

Tinidazole Powder CAS 19387-91-8

Product Name:Tinidazole powder
CAS NO.:19387-91-8
Molecular Formula:C8H13N3O4S
EINECS.NO:243-014-4
Synonym:1-(2-(Ethylsulfonyl)ethyl)-2-methyl-5-nitro-1H-imidazole;TIMTEC-BB SBB006917;TINIDAZOLE;bioshik;Fasigin;Simplotan;Tinidazol
Lead Time:1-3 days
Shipping:DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea etc
Store & Shelf life:Cool & dry place;36 months
Other:There are warehouses in the United States, Australia and Germany
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Description

what is Tinidazole powder?

Tinidazole powder is a white or light yellow crystalline or crystalline powder; The taste is slightly bitter. It is often used in combination with other anti aerobic drugs to treat sepsis, respiratory infections, pelvic infections, unclean abortion, cellulitis, etc. caused by various anaerobic bacteria

MF of Tinidazole powder CAS 19387-91-8

Product name

Tinidazole

CAS

19387-91-8

Molecular formula

C8H13N3O4S

Molecular weight

247.27
EINECS 243-014-4

Appearance

Grey white to light yellow powder

Melting point 

118-120°C

Storage

Sealedindry,RoomTemperature

Desity

1.4338(roughestimate)

 

What is Tinidazole powder used for?

trichomonas

Tinidazole powder has a significant killing effect on various common pathogenic anaerobic bacteria and trichomonas, and its activity is 2-4 times stronger than Metronidazole,
The therapeutic effect on amoebic dysentery and extraintestinal amoebic disease is comparable to Metronidazole, but the toxic side effects are significantly lower than Metronidazole.
Compared with Metronidazole, tinidazole has a longer duration of efficacy and is generally administered 1-2 times. Adverse reactions of tinidazole are less common and mild compared to metronidazole, with occasional mild gastrointestinal reactions, headaches, dizziness, skin itching, rash, constipation, and overall discomfort. These side effects usually disappear quickly after discontinuing the medication.

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what is the mechanism of action of Tinidazole powder?

Mechanism Of Action Of Tinidazole

Tinidazole powder can inhibit the oxidation-reduction reaction of protozoa, causing the nitrogen chain of protozoa to break and exert its bactericidal effect; After drugs enter susceptible microbial cells, their nitro groups are easily reduced by electron transfer proteins to amino groups with cytotoxic effects in anaerobic or low oxygen environments and lower redox potentials. This inhibits the synthesis of cellular DNA, lowers the price of synthesized DNA, destroys the double helix structure of DNA or blocks its transcription and replication, leading to cell death and exerting its role in killing anaerobic bacteria and effectively controlling infections

 

Product Specification

Items

Specifications

Results

Appearance

White powder

Complies

Related substance

(HPLC)

98%min

99.8%

Odor

Characteristic

Complies

Assay

98%

98.22%

Sieve analysis

100% pass 80 mesh

Complies

Loss on drying

1.0% min

0.21%

Sulfated ash 

≤0.1%

0.04%

Assay

≥99%

99.5%

Heavy Metal

<10ppm

Complies

As

<0.1ppm

0.05ppm

Pb

<0.1ppm

0.05ppm

Cd

<0.1ppm

0.05ppm

Residual Solvents

<100ppm

Complies

Residual Pesticide

Negative

Complies

Total Plate Count

<1000cfu/g

Complies

Yeast & Mold

<100cfu/g

Complies

E.Coli

Negative

Complies

Salmonella

Negative

Complies

Conclusion:Conform with specification and qualified.

 

What are the in vitro studies of Tinidazole powder?

Tinidazole powder kills metronidazole sensitive strains at low MLC, but can only effectively combat 4 out of 12 metronidazole resistant strains. Tinidazole exhibits activity against pathogenic protozoa (such as Tricomomonas vaginalis, Entamoeba bistolytica, Giardiaduodenalis), a wide range of clinically significant anaerobic bacteria (such as Bacteroides fragilis, Clostridium difficile), and microaerophilic Helicobacter pylori. In sensitive protozoan and bacterial cells, Tinidazole is reduced to a cytotoxic intermediate that covalently binds to DNA, leading to irreversible cell damage. Tinidazole inhibited 104 T. vaginalis isolates with an average MLC of 1014.9 μ M. Tinidazole powder affects the morphology, compliance, and feasibility of the nourishing body on Giardiaduodenilis. Tinidazole exhibits activity against 40 clinical isolates of Clostridium difficile, 10 Prevotellabiia, and 11 Bacteroides fragilis

 

How and where to buy Tinidazole powder?

We have 8 years of experience in selling legal scientific research drugs and have a good reputation, making us a trustworthy partner.
We ensure the quality of our products through independent experimental testing, and every customer is our VIP.

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A variety of shipping methods for you to choose

Transportation Time

Shipping method

Cargo weight requirements

Advantage

3-7 days

DHL, Germany DHL, Germany DPD,
UPS, USPS,FedEx, TNT,EMS

Suitable for under 50kg.
International door to door express

We have warehouses in Germany and California, USA,
and customers in Europe and America can
enjoy sending goods directly from these two places.

7-15 days

By Air

Suitable for more than 50kg.
fast and cheaper for large order

15-60 days

By Sea

Suitable for more than 500kg.
Cheapest shipping way

 

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Note: The product is for research use only and is not intended for diagnosis, treatment, disease prevention, etc.

 

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