Oxytetracycline Hydrochloride Powder was patented in 1949 and put into commercial use in 1950. Its active ingredient is oxytetracycline, which is well known in the list of essential drugs of the World Health Organization all year round. Oxytetracycline is a broad-spectrum tetracycline antibiotic that works by interfering with the ability of bacteria to produce essential proteins. Without these proteins, bacteria cannot grow, reproduce and increase in number. Therefore, oxytetracycline can prevent the spread of infection, and the remaining bacteria will be killed by the immune system or eventually die. Oxytetracycline, as a broad-spectrum antibiotic, is active against a variety of bacteria. However, some bacterial strains have developed resistance to the antibiotic, which reduces its effectiveness in treating some types of infections and needs to be used in conjunction with other products.
| structural formula |
|
|
|
Items |
Standards |
Result |
|
Appearance |
Sticky yellow crystalline powder |
Conform |
|
Identification |
The IR absorption spectrum should correspond with reference spectrum |
Conform |
|
Organic volatile impurity |
<1% |
Negative |
|
Product activity |
≥ 98% (calculated on the dried basis) |
99.89% |
|
Loss on drying |
≤ 0.5% |
0.05% |
|
Residue on Ignition |
≤ 0.1% |
0.02% |
|
Heavy metals |
<10ppm |
5ppm |
|
Total bacteria count |
<1000 cfu/g |
1.28 cfu/g |
|
Yeast and Moulds |
<100 cfu/g |
0.8 cfu/g |
|
Escherichia Coli |
Negative |
Negative |
|
Salmonella |
Negative |
Negative |
| Conclusion： |
Conform with enterprise specification . |
How is Oxytetracycline Hydrochloride used to treat wild animals?
Historically, Oxytetracycline Hydrochloride Powder has been used to control the outbreak of bedbugs in Central America and Europe. Oxytetracycline can also be used to correct respiratory disorders in livestock. It is administered in powder form or by intramuscular injection. Our livestock producers use oxytetracycline in livestock feed to prevent diseases and infections in cattle and poultry. Moreover, antibiotics will not be completely digested, some will be absorbed by the gastrointestinal tract of animals, and the rest will be deposited in feces. Researchers from the agricultural research service studied the decomposition of oxytetracycline in manure according to various environmental conditions. They found that the decomposition rate slowed down with the increase of fecal saturation, and concluded that the level of oxygen would affect the effect of antibiotics. At the same time, oxytetracycline can also be used to label fish released and subsequently recaptured. Oxytetracycline can interfere with bone deposition and leave obvious marks on growing bones.
Oxytetracycline 200 (tm200) has also been formulated as a broad-spectrum anti-infective drug for fish. It is used to control some potential diseases of salmon, catfish, and lobster.
What adverse reactions may oxytetracycline hydrochloride have?
The main adverse reactions of Oxytetracycline Hydrochloride Powder are that this product can be deposited in teeth, bones, and nails, causing varying degrees of discoloration and yellow staining of teeth, enamel dysplasia and dental caries, and bone dysplasia. Oral administration of these drugs can cause nausea, vomiting, upper abdominal discomfort, abdominal distension, diarrhea, and other gastrointestinal symptoms. The long-term application of this product can reduce the normal flora in the human body, resulting in vitamin deficiency, fungal reproduction, dry mouth, sore throat, angular stomatitis, glossitis, dark or discolored tongue coating, and other problems. Severe cases may cause double infection, that is, long-term application of oxytetracycline hydrochloride can induce digestive tract, respiratory tract, and urinary tract infection of drug-resistant staphylococcus aureus, gram-negative bacilli, and fungi, and severe cases can cause sepsis. Taking it for a short time has less impact on the liver, kidney, and other important organs, but there are also precedents of aggravating hepatic steatosis and azotemia in the clinic. At the same time, it is prone to hepatotoxicity for pregnant women, high-dose drug users, and patients with original renal function damage,
The use of ineffective or degraded oxytetracycline hydrochloride can cause Fanconi syndrome, that is, renal tubular acidosis, which is characterized by polyuria, nausea, thirst, diabetes, amino acid urine, hyperphosphaturia, hypokalemia, hyperuricemia, acidosis, and proteinuria.
How should we deal with tetracycline teeth formed after long-term use of oxytetracycline hydrochloride?
Tetracycline teeth are pigmentation caused by taking tetracycline drugs for a long time, which makes the product react with tooth tissue and color the teeth, resulting in blackening, yellowing, or missing teeth during tooth growth and development. In this case, the treatment methods we can use are as follows: 1. Bleaching treatment: it is suitable for those with light tooth coloring, and no enamel hypoplasia. Treatment can be divided into internal bleaching and external bleaching. Internal bleaching is placing bleach inside the teeth, and the clinical results are good. 2. Veneer treatment: it can be applied to enamel hypoplasia, but the results are poor for teeth with serious tetracycline staining. This treatment needs to grind off a small amount of enamel and paste resin, porcelain, and other materials on the tooth surface. The manufacturing requirements are high, and the tooth shape and color are better. This is also a method of whitening tetracycline teeth. 3. Porcelain fused to metal crown restoration: it is applicable to all tetracycline teeth with good shading results, but certain tooth tissues need to be ground away, which may cause some inflammation. Some dentists believe that to avoid inflammation, it is possible to change the living pulp teeth into pulpless teeth before crown repair. At present, porcelain fused to metal crowns is generally used in the restoration of porcelain fused to metal crowns. The color after restoration is realistic, but the price is high and the process is complex.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
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