Levofloxacin Hydrochloride CAS 177325-13-2
Product Name:Levofloxacin hydrochloride
Synonym:ac-7617;s454;EINECS 605-797-4;levofloxacin hcl
CAS NO.:177325-13-2
EINECS NO.:605-797-4
Molecular Formula:C18H21ClFN3O4
Purity & Grade: 99%; Medicine grade
Character:White Powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 100g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-15 days
Store & Shelf life: Cool & dry place; 24 months
Description
Product description

Levofloxacin hydrochloride is the levobortant of Ofloxacin, and its antibacterial activity is about twice that of Ofloxacin. Its main mechanism of action is to inhibit the activity of bacterial DNA rotase (bacterial topoisomerase II) and hinder bacterial DNA replication. It has the characteristics of wide antibacterial spectrum and strong antibacterial action.
Levofloxacin hydrochloride has strong antibacterial activity against most Enterobacteriaceae bacteria, such as Escherichia coli, Klebsiella, Serratia, Proteus, Shigella, Salmonella, Citrobacter, Acinetobacter, and gram-negative bacteria such as Pseudomonas aeruginosa, Haemophilus influenzae, gonorrhea, etc. It also has good antibacterial effect on some gram-positive bacteria such as methicillin-sensitive Staphylococcus, Streptococcus pneumoniae, Streptococcus pyogenes, hemolytic streptococcus and Legionella, mycoplasma and chlamydia. But it has poor effect on anaerobic bacteria and enterococcus.

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COA
| ltems | Standard | Results |
| Appearance | White to off-white crystalline powder | Conforms |
| Specific rotation | -47.0°~-52.0° | 51.0° |
| PH | 3.5~5.0 | 3.9 |
| Loss on drying | 3.5~5.0% | 3.90% |
| Residue on ignition | ≤0.1% | 0.04% |
| D-Isomer | ≤1.0% | 0.28% |
| Related substances | Total impurities≤0.5% | 0.14% |
| Residual solvent | Ethanol≤5000ppm | 89ppm |
| DMSO≤1000ppm | N.D | |
| Chloroform≤600ppm | N.D | |
| Heavy metals | ≤10ppm | <20ppm |
| Assay | Levofloxacin 89.2~92.5% | 90.50% |
| Conclusion | Conform with the enterprise standard | |

Boiling point 571.5ºC at 760 mmHg
Molecular formula C18H21ClFN3O4
Molecular weight 397.828
Flash point 299.4ºC
Precise mass 397.120453
PSA 75.01000
LogP 2.34890
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What is levofloxacin HCL use for?
Levofloxacin hydrochloride is FDA-approved for the treatment of nosocomial pneumonia, community-acquired pneumonia, acute bacterial rhinosinusitis, acute bacterial exacerbation of chronic bronchitis, acute bacterial prostatitis, acute pyelonephritis, urinary tract infection, skin or skin structure infections, prophylaxis.
What is the most common side effect of levofloxacin?
Common levofloxacin side effects include nausea, headaches, and sun sensitivity. Diarrhea and insomnia are also possible. Levofloxacin also has more rare, but serious side effects to look out for. It can cause tendon and nerve pain and may also affect your heart or liver.
Does levofloxacin reduce inflammation?
Levofloxacin inhibits proliferation and induces the apoptosis of inflammatory FLS. At the same time, levofloxacin revealed anti-inflammatory, apoptosis and degradation effects. This is due to their inhibitory effects on proliferation and inflammation.
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Package

Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
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