Ciprofloxacin hydrochloride hydrate Introduction
Xi'an Faithful BioTech Co., Ltd. is an export-oriented biotechnology and chemical trading company headquartered in Xi'an, Shaanxi Province, China. Founded in 2018, the company focuses on providing pharmaceutical intermediates, plant extracts, food additives, and feed ingredients to the global B2B market.
As a lean, professional supplier, we implement rigorous quality control to ensure batch stability and compliance. With an experienced international sales team, we offer highly competitive prices, reliable delivery times, and one-stop export services.
Our products are widely supplied to the pharmaceutical, health supplement, cosmetic, and feed industries in Europe, North America, Southeast Asia, and the Middle East.
Ciprofloxacin hydrochloride hydrate is a white or slightly yellow crystalline powder. It is highly soluble in water. CAS:86393-32-0; Molecular formula: C17H21ClFN3O4; Molecular weight: 385.82; EINECS: 617-845-1. Ciprofloxacin hydrochloride hydrate powder was first developed by Bayer of Germany in 1983 and belongs to the third-generation 4-QUINOLONE type active raw material. Industrial synthesis generally uses 3-Chloro-4-fluoroaniline as the starting material, and through multiple organic reactions, the finished product is obtained; The market high-purity powder has strict control over indicators, with the effective substance content not being lower than 98.0%, and the moisture range is stably maintained at 4.7% to 6.7%. This moisture range can ensure the stability of the material during long-term storage and prevent deterioration.
This category is the core basic raw material for preparing antibacterial finished products, and can be used to process various formulations such as oral and topical applications. It is used for various research scenarios related to body infections caused by sensitive bacterial strains, covering urinary, respiratory, digestive tract, bone and joint, and soft tissue-related inflammations, and is also applicable to experiments related to systemic bacteremia.
What is the mechanism of action of Ciprofloxacin hydrochloride hydrate?
The active mechanism of Ciprofloxacin hydrochloride hydrate lies in its ability to specifically inhibit two key replication enzymes of bacteria: DNA gyrase and topoisomerase IV. When bacteria divide and multiply, they rely on these two enzymes to unwind and align the circular DNA strands, thus enabling the replication of genes and cell division. Iprofloxacin hydrochloride hydrate powder can directly bind to the complex formed by the enzyme and DNA, blocking the process of DNA unwinding and preventing the bacterial gene replication and transcription process.
After the DNA replication chain is broken, the bacteria cannot complete their proliferation, and at the same time, DNA fragments accumulate, directly inducing the breakdown and apoptosis of the bacteria, thereby achieving a broad-spectrum inhibitory effect on various Gram-positive and Gram-negative pathogenic bacteria.
Compared with similar 4-QUINOLONE raw materials, it has a stronger affinity for the DNA gyrase of Gram-negative bacteria, and has a more prominent inhibitory effect on common pathogenic bacteria in the intestines, urinary tract, and respiratory tract. In addition, it can penetrate the outer membrane lipopolysaccharide layer of bacteria and more easily enter the bacterial interior to act on the target site. At low concentrations, it can produce a stable antibacterial effect.
What are the uses of Ciprofloxacin hydrochloride hydrate?
Ciprofloxacin hydrochloride hydrate is mainly used for processing various oral and topical skin and mucous membrane antibacterial preparations, suitable for the production of finished products related to bacterial infections in multiple body parts such as the respiratory tract, urinary tract, and digestive tract; it is also a commonly used research reagent in laboratories, which can be used as a standard control substance to conduct Gram-positive and Gram-negative bacterial susceptibility tests, and be used for in vitro and in vivo related research such as the mechanism of action of bacterial DNA replication enzymes, screening of pathogenic bacteria activity, and the combined synergistic effect of antibacterial agents. Ciprofloxacin hydrochloride hydrate powder has a prominent inhibitory effect on common pathogenic bacteria in the intestines, urinary tract, and respiratory tract, can take effect through penetrating the bacterial outer membrane, and can exert a stable antibacterial effect at low concentrations, and can only be used for aquatic bacterial inhibition-related research in compliant experimental scenarios, and is not recommended for direct application in large-scale farming.
It has strong antibacterial activity against Escherichia coli, Klebsiella, and other Enterobacteriaceae; its antibacterial effect against Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae is better than Norfloxacin and Pefloxacin. It is used for otitis media, external otitis, and tympanic membrane inflammation caused by sensitive bacteria. There may be occasional symptoms of middle ear pain and itching.
MF of Ciprofloxacin hydrochloride hydrate
| CAS | 86393-32-0 |
| Molecular formula | C17H21ClFN3O4 |
| Molecular weight | 385.82 |
| EINECS | 617-845-1 |
| Melting point | 318-320 °C |
Specification
| Item | Specification | Result |
| Description | white or slightly yellow crystalline powder | Complies |
| Assay | ≥99.0% | 99.62% |
| Identification | VS | Complies |
| IR | Complies | |
| PH | 4.0~5.0 | Complies |
| Solution | Should clarify | Complies |
| Single impurity | ≤0.8% | 0.63% |
| Total impurity | ≤1.0% | 0.75% |
| Loss on drying | ≤5.0% | 0.44% |
| Conclusion | Conform with enterprise specification | |
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A variety of shipping methods for you to choose
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS |
Suitable for under 50kg. International door to door express |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order |
|
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Ciprofloxacin hydrochloride hydrate powder etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.
FAQ:
Q1:What are the adverse reactions of Ciprofloxacin hydrochloride hydrate?
It may cause tendinitis or tendon rupture, affect the central nervous system, and cause peripheral nerve disorders, etc.
Q2:Where does the antibacterial advantage of Ciprofloxacin hydrochloride hydrate lie?
It delivers stronger inhibition against Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae, with better bacterial outer membrane penetration.
Q3:Can Ciprofloxacin hydrochloride hydrate be used for antibacterial purposes in large-scale aquaculture?
No, it is only allowed for compliant lab aquatic research, not direct application in commercial farming.
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