Medroxyprogesterone Acetate Raw Hormone Powder (MPA) is used as a method of birth control and as a part of menopausal hormone therapy. Depo-Provera is also used to treat endometriosis, abnormal uterine bleeding, abnormal sexuality in males, and certain types of cancer. As a kind of progestin hormone medicine, this product can be used alone or in combination with estrogen.
| Molecular formula |
|
|
|
Item |
Specification |
Result |
|
Characters |
White crystal powder |
White crystal powder |
|
Identification |
Conform |
Conform |
|
Appearance of solution |
Clear and colourless |
Clear and colourless |
|
Melting range ℃ |
≥ 200 |
206.8 |
|
Acidity |
≤1 |
<1 |
|
Related substances[Ignore(<0.05)]: |
||
|
Impurity A(%) |
≤0.1 |
Not detected |
|
Impurity B(%) |
≤0.1 |
Not detected |
|
Impurity C(%) |
≤0.1 |
Not detected |
|
Impurity D(%) |
≤0.1 |
Not detected |
|
Other single impurity (%) |
≤0.1 |
Not detected |
|
Total impurity(%) |
≤0.5 |
Not detected |
|
Heavy metals (ppm) |
≤20 |
<20 |
|
Loss on drying(%) |
≤0.5 |
0.03 |
|
Residue on ignition (%) |
≤0.1 |
0.04 |
|
Assay(HPLC) (%) |
97.0-102.0 |
99.6 |
| Conclusion： |
Conform with enterprise specification . |
Do you know the harm of abortion?
No matter what form of abortion, it will cause ultimate damage to the body. The most serious damage is caused by artificial abortion, mainly including endometriosis, menstrual disorder, dystocia, and placenta retention, as well as the most serious uterine perforation, cervicitis, and cancer. Medical abortion brings less pain to patients, and it is safe and convenient. It is a common method to terminate pregnancy for patients with an accidental pregnancy and early pregnancy. The group of people who use it is also expanding. However, the damage to your body still exists. After a medical abortion, the decrease of human chorionic gonadotropin and the increase of estrogen in the blood of patients are slow, and the shedding speed of decidua and a chorionic membrane is slow, resulting in more vaginal bleeding and long bleeding time. The whole uterine environment is greatly damaged, affecting the repair of the endometrium. No more than 3 times in the first 2 years of pregnancy.
The effect of this product on abortion contraception
Medroxyprogesterone Acetate Raw Hormone Powder is a synthetic luteal progesterone. The raw material is white or almost white crystalline powder, which is very soluble in chloroform, acetone, ethyl acetate, slightly soluble in absolute ethanol, and insoluble in water. Angong progesterone can quickly repair the endometrium. Withdrawal bleeding may occur when the drug is stopped after a period of time. The reason is that the endometrial layer is completely shed and a small amount of residual tissue in the uterus is taken out together, thus playing the role of medical curettage. It can replace the curettage and assist the anti-infection treatment, reduce the complications of medical abortion and rapidly reduce bleeding, Because of its wide clinical feasibility, it can also be used to treat irregular menstruation and dysmenorrhea
The drug can increase the viscosity of cervical mucus; It can also inhibit the release of adenohypophyseal luteinizing hormone (LH) through the negative feedback effect on the hypothalamus so that the follicles can not mature and inhibit ovarian ovulation. Therefore, it has a contraceptive effect. When the drug concentration in the blood exceeds 0.1g/l, LH and estradiol (E2) are inhibited, which leads to ovulation obstruction.
About the anti-tumor effect of this product
Medroxyprogesterone Acetate Raw Hormone Powder is commonly used for palliative treatment or adjuvant treatment of inoperable, recurrent, or metastatic hormone-dependent tumors, such as breast cancer, endometrial cancer, renal cancer, and prostate cancer.
Studies have shown that long-term use of this product in the treatment of endometrial cancer can activate the epidermal growth factor receptor, thus playing a therapeutic role. In addition, it can play a synergistic role in anti-tumor when used in combination with other drugs, such as 1. It can protect the bone marrow during tumor chemotherapy. By inhibiting the mitotic activity and differentiation of bone marrow stem cells, the cells can be in a quiescent phase, so that the leukocytes during chemotherapy are not significantly reduced, the tolerance of chemotherapy is improved, and the successful completion of chemotherapy is guaranteed. 2. Reduce the digestive tract reaction caused by chemotherapy: the use of this product after chemotherapy can significantly improve the appetite, weight and general condition score of patients with advanced gastric cancer compared with patients with chemotherapy alone, and the incidence and severity of the gastrointestinal reaction and bone marrow suppression are relatively low. Moreover, this short-term intermittent medication has no obvious liver and kidney function damage or deep vein thrombosis. 3. Inhibitory effect on the growth of human colon cancer LS174T cells in vivo: after using this product, it has a significant inhibitory effect on the growth of human colon cancer transplanted tumor LS174T cells and induces apoptosis. The mechanism may be related to the arrest of LS174T cells in the G1 phase by medroxyprogesterone and the up-regulation of Fas and FasL expression on the cell surface. 4. Enhance the anti-tumor effect of cisplatin on human ovarian cancer drug-resistant cells: This product can obviously reverse the resistance of human ovarian cancer drug-resistant cells to cisplatin in vivo, and the mechanism may be related to its ability to induce cell apoptosis and increase the accumulation of cisplatin in cells. 5. Inhibition of pelvic pathological angiogenesis: This product has an obvious inhibitory effect on pelvic pathological angiogenesis of ovarian cancer; Combined chemotherapy can prolong the survival time of patients with ovarian cancer; The pathological vessels of the pelvic cavity shown by internal iliac arteriography can be used as an index to evaluate the therapeutic effect and prognosis.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Medroxyprogesterone Acetate Raw Hormone Powder etc. at a more favorable price. If you are interested, please leave a message.
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