what is estriol powder usp?
Estriol is one of the three main estrogens in human beings. Metabolites of estradiol and estrone. Among estrone, estradiol and estriol, estriol has the weakest activity. It exists in urine, and the content is higher in urine during pregnancy. Estriol powder usp is white powder.
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Product name |
estriol |
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CAS |
50-27-1 |
|
|
Molecular formula |
C18H24O3 | |
|
Molecular weight |
288.38 | |
| EINECS | 200-022-2 | |
|
Appearance |
white crystalline powder |
|
| Melting point | 280-282 °C(lit.) | |
| Density | 1.27g/cm3(Predicted) |
What is the uses of estriol powder usp?
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estriol powder usp can be used for cervical inflammation, especially for menopausal syndrome and senile vaginitis. It can also be used as an adjuvant medication for mid-term induction and induced abortion, It can also be used for prostate enlargement, prostate cancer, etc. In addition, it also has the function of rapidly increasing peripheral white blood cells It is effective in treating leukopenia caused by chemotherapy or radiotherapy, as well as reducing vascular permeability and fragility, and can be used for the treatment of various types of bleeding. It has a rapid hemostatic effect on excessive menstruation, tonsillectomy, or hysterectomy. If you need it, pls click e-mail sales1@faithfulbio.com |
Product Specification
| Items | Specifications |
Result |
|
Appearance |
White to practically white, odorless, crystalline powder. |
white crystalline powder, odorless |
|
Identification |
A:IR B:UV |
Conforms |
|
Melting point |
About280ºC |
281.5ºC |
|
Solubility |
Insoluble in water; sparingly soluble in alcohol; soluble , n ether, and in vegetable oils |
Conforms |
|
Completeness of solution |
The solution is clear and free from undissolved solid. |
Conforms |
|
Loss on drying |
≤0.5% |
0.26% |
|
Specific optical rotation |
+54°~ +62° |
+57.07° |
|
Total impurities |
≤2.0% |
Conforms |
|
Residue on ignition |
≤0.1% |
0.06% |
|
Assay |
≥98% |
98.63% |
how about the Mechanism of Action of estriol powder usp?
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Estriol levels can be measured to give an indication of the general health of the fetus. If levels of "unconjugated estriol" are abnormally low in a pregnant woman, this may indicate a problem with the development of the child. Estriol powder usp interacts with a target cell receptor. When the estrogen receptor has bound its ligand it can enter the nucleus of the target cell, and regulate gene transcription which leads to formation of messenger RNA. The mRNA interacts with ribosomes to produce specific proteins that express the effect of estriol upon the target cell. Estrogens increase the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins and suppress follicle-stimulating hormone (FSH) from the anterior pituitary. |
How to produce estriol powder usp?
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Step 1: Prepare estrone diacetate compounds by reacting Estrone with Isopropenyl acetate; Step 2: React the estrone diacetate compound with N-Bromosuccinimide to prepare 16 bromoacetoestrone; Step 3: The 16 bromoacetoestrone is reacted in an environment of sodium hydroxide and solvent A to prepare 17,17-2-METHOXYESTRADIOL; Step 4: The 17,17-2-METHOXYESTRADIOL undergoes hydrolysis reaction with strong acid to obtain 16 α - Hydroxy Estrone; Step 5: The 16 α - Hydroxy Estrone undergoes a reduction reaction to obtain estriol powder. |
How and where to buy estriol powder usp?
We have 8 years of experience in selling legal scientific research drugs and have a good reputation, making us a trustworthy partner.
We ensure the quality of our products through independent experimental testing, and every customer is our VIP.
Send your Inquiry for more information, Click email：sales1@faithfulbio.comNow.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
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Note: The product is for research use only and is not intended for diagnosis, treatment, disease prevention, etc.
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