What is 99% Ethynyl Estradiol ?
99% Ethynyl Estradiol is white to white crystalline powder with fine texture and good fluidity. The molecular formula is CHO and the molecular weight is 296.40. As the key raw materials of steroid hormones, we use high-standard chemical synthesis process to prepare them, so as to prevent the introduction of impurities from the source and ensure high purity and safety. Its mechanism of action is that it is widely used as a potent estrogen receptor agonist in contraceptive products and hormone replacement therapy, and also plays an important role in the treatment of prostate cancer and postmenopausal syndrome. Relying on the whole process data closed loop and dual risk control system of Xi'an Faithful BioTech Co., Ltd., we ensure that each batch of products has excellent crystal stability and batch consistency to protect your preparation production. For consultation or order, please contact us.
| Product name | 99% Ethynyl Estradiol powder |
| CAS | 57-63-6 |
| structural formula | C20H24O2 |
| molecular weight | 296.41 |
| EINECS | 200-342-2 |
| melting point | 182-183 °C(lit.) |
| boiling point | 378°C (rough estimate) |
| Acidity coefficient (pKa) | pKa 10.32 (Uncertain) |
| density | 1.0944 (rough estimate) |
| Storage condition | room temp,keep dry |
How is 99% Ethynyl Estradiol prepared ?
1. Traditional ways
raw materials preparation
Using estrone as the starting material, potassium acetylene was produced by azeotropic dehydration (8 hours) with sterile solvent.
React with potassium acetylide at low temperature (25-40℃) to generate crude ethinyl estradiol.
Purification treatment：After adjusting the acidity, high-purity products were obtained by steam distillation, neutralization and crystallization.
2. One-step acetylization method
reaction condition：Dissolving estrone in organic solvent, adding organic base, and performing alkynylation at-20-30℃.
aftertreatment：After the reaction, the acid solution is neutralized, concentrated and separated out by water, refined by organic solvent and dried to obtain the finished 99% Ethynyl Estradiol powder.
Summary: At present, industrial production is mainly based on these two methods, the former realizes efficient synthesis, and the latter simplifies the reaction steps and reduces energy consumption.
What is the use and efficacy of 99% Ethynyl Estradiol ?
It is like a powerful estrogen that "refuels" the body. It is mainly to help those friends whose estrogen in the body is "in a hurry" to solve the trouble. For example, when a female friend reaches the age, it can come in handy for "menopausal tantrums" (hot flashes, night sweats, upset and insomnia), menstrual fasting (amenorrhea), or the problem that it is difficult to prepare for pregnancy. In addition to conditioning, 99% Ethynyl Estradiol powder is also an "auxiliary player" against the disease. For some advanced breast and prostate problems, it can help stabilize the situation. Of course, after all, this is a "warrior" who regulates body hormones. It is suggested that we must first look at the specific situation of the body before deciding whether to invite this "foreign aid" to help.
Product Specification
| Items | Specifications | Results | ||
| Appearance | white powder | Complies | ||
| Assay | 98%-101% | 99.58% | ||
| Loss on Drying | ≤5.0% | 0.07% | ||
| Residue on Ignition | ≤0.1% | 0.04% | ||
| Heavy metals | ≤10ppm | 5ppm | ||
| As | ≤1ppm | ≤1ppm | ||
| Pb | ≤1ppm | ≤1ppm | ||
| Cd | ≤1ppm | ≤1ppm | ||
| Hg | ≤0.1ppm | ≤0.1ppm | ||
| Total Plate count | ≤1000CFU/g | <10CFU/g | ||
| Yeast &Mould | ≤100CFU/g | <10CFU/g | ||
| Escherichia Coli | Negative | Negative | ||
| P.aeruginosa | Negative | Negative | ||
| S.aureus | Negative | Negative | ||
| Salmonella | Negative | Negative | ||
| Conclusion: The test results are conformed to the in-house specification | ||||
Click email : sales7@faithfulbio.com Or WhatsApp：+86 13137770562
How and where to buy 99% Ethynyl Estradiol powder wholesale ?
You can trust us completely because we have a good record in selling legal education drugs. Over the years, we have reached Many orders cooperation between Europe and America, which is safe and fast. Have safeguard.
Reasons for choosing us: reliable strength supply, high quality and stable storage, worry-free supply and timely delivery after sale.
A variety of shipping methods for you to choose
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL, Germany DHL, Germany DPD, UPS, USPS, FedEx, TNT, EMS | Suitable for under 50kg. International door to door express | We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order | |
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
Send your Inquiry for more details , Click email : sales7@faithfulbio.com Or WhatsApp：+86 13137770562
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Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
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