Raw Material Hexapeptide-10 CAS 146439-94-3

Raw Material Hexapeptide-10 is a synthetic oligopeptide composed of six amino acids (serine-isoleucine-lysine-valine-alanine-valine, sequence SIKVAV). It simulates the active fragment of laminin α chain and is a signal peptide, which is mainly used as cosmetic raw material. Research shows that its core function lies in firming, anti-wrinkle and repair. That is to say, by increasing the synthesis of laminin V and α6- integrin, the dermal-epidermal connection is strengthened, and the firmness and elasticity of skin are improved, thus improving relaxation and wrinkles. At the same time, it can also promote the proliferation and migration of keratinocytes and fibroblasts, accelerate the repair of skin barrier, and help to dilute acne marks and improve uneven skin color. In addition, it also helps to improve skin microcirculation and make skin healthier and more shiny.

What is the mechanism of Raw Material Hexapeptide-10?

Raw Material Hexapeptide-10 is a synthetic hexapeptide that mimics the active fragment of laminin α chain. Its mechanism of action is mainly around the core of "strengthening dermal-epidermal junction", and it can achieve compact anti-wrinkle and repair through multi-channel synergy.
1.Core mechanism: strengthening dermal-epidermal junction
Hexapeptide -10 can significantly increase the synthesis of laminin V and α6- integrin, which are the key components of basement membrane and hemidesmosomes. By promoting its expression, hexapeptide -10 can effectively strengthen the connection between dermis and epidermis, make the skin structure more compact, thus improving compactness and elasticity and improving relaxation and wrinkles.
2.Promote cell proliferation and migration
As a chemotactic peptide, hexapeptide -10 can induce cell aggregation and stimulate the adsorption, growth and migration of basement membrane cells. Studies have shown that it can make keratinocytes proliferate about 38% and fibroblasts proliferate about 75%. This ability to promote cell regeneration is helpful to accelerate the repair of skin barrier, and has a positive effect on fading acne marks and improving uneven skin color.
3.Synergistic improvement of skin microcirculation
Hexapeptide -10 also helps to improve skin microcirculation and make skin healthier and brighter. By strengthening the intercellular connection, it can improve the problem of insufficient nutrient delivery caused by aging, thus alleviating the signs of aging such as dull skin, yellowing and weakened elasticity.

Is Raw Material Hexapeptide-10 safe?

In terms of safety, Hexapeptide-10 powder is safe and well tolerated in cosmetics, and is suitable for sensitive muscles. However, we still recommend skin test behind the ear or inside the arm to confirm that there is no discomfort before using it on the whole face. Among them, its risk coefficient in cosmetics is 1. This conclusion is based on the four-step standard risk assessment procedure of hazard identification, dose response evaluation, exposure assessment and risk characterization. Moreover, "risk coefficient is 1" is a qualitative conclusion, which is not calculated by a fixed formula. It means that after strictly following the four-step standard risk assessment procedure, hexapeptide -10 is judged as a component with extremely low risk and high safety, so it can be safely added and used in cosmetics. In addition, it lacks special research for pregnant women and lactating people. For safety reasons, it is recommended that this group consult a doctor before using it.

How long will the effect of Raw Material Hexapeptide-10 ?

Raw Material Hexapeptide-10 powder , as an ingredient of skin care products for external use, takes a certain time to show its effect, and usually follows the following rules:
1.Preliminary feeling (about 2-4 weeks): after continuous use, you can initially feel the improvement of skin firmness, smoothness and elasticity, and the fine lines are faded.
2.Significant improvement (about 4-8 weeks): With the extension of use time, the skin density and compactness will be improved more obviously, and the wrinkle depth and roughness will be further reduced.
3.Long-term effect: In order to achieve the ideal anti-aging and repair effect, it is recommended to stick to it for at least 8-12 weeks, and cooperate with daily sun protection and moisturizing.

What are the factors that affect the effective time of Raw Material Hexapeptide-10 ?

Individual differences: age, skin aging, metabolic rate, etc. will all affect the effective time.
1.Product formula: the concentration of Raw Material Hexapeptide-10 in the product, the formula technology and whether it contains other synergistic ingredients will all affect the final effect.
2.Usage habits: Whether to insist on daily use and whether to cooperate with basic care such as sun protection is the key to the sustainability of the effect.

A variety of shipping methods for you to choose

Our strengths:

Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Raw Material Hexapeptide-10 Powder etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.

FAQ:

Q1. How to save and use it?
Storage: raw powder should be sealed, protected from light and moisture, and stored at 2-8 C or-20 C; It is suggested that the dissolved solution be stored at-20 C after sub-packaging to avoid repeated freezing and thawing.
Usage: It can be added to skin care products such as essence, cream, emulsion, etc. The recommended addition amount is 0.005-0.05%, which needs to be adjusted according to the formula and skin quality.
Q2. Can it match other ingredients?
Sure. Hexapeptide-10 can be compounded with vitamin C derivatives, nicotinamide, hyaluronic acid, etc., to enhance the anti-wrinkle, repair and moisturizing effects. However, it is necessary to pay attention to the pH value of the formula (recommended 5.5-7.0) to avoid direct mixing with strong acidic components.
Q3. What's the difference between it and hexapeptide -1 and hexapeptide -2?
Hexapeptide -1, Hexapeptide -2 and Hexapeptide -10 are all hexapeptides, but their amino acid sequences and functions are different. Hexapeptide -10 Powder is mainly aimed at dermal-epidermal junction to strengthen skin firmness; Hexapeptide -1 and Hexapeptide -2 are more focused on whitening and antioxidation. The three can be used in combination to realize multi-channel skin care.

Disclaimer: The information published on this website comes from the internet, which does not mean that this website agrees with its views or confirms the authenticity of the content. Please pay attention to distinguish it. In addition, the products provided by our company are only used for scientific research. We are not responsible for the consequences of any improper use.

If you are interested in our products, or have critical suggestions on our articles or are not completely satisfied with the products received, please contact us by Email ：sales6@faithfulbio.com   . Our team is committed to ensuring the complete satisfaction of customers.

Hot Tags: raw material hexapeptide-10 cas 146439-94-3, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China