What is Pentapeptide-3 Powder?
Xi'an Faithful BioTech Co., Ltd. is situated in Xi'an, the birthplace of the ancient Silk Road. Leveraging the city's mature logistics network and abundant fine chemical industrial resources, our enterprise has grown into an integrated fine chemical provider that delivers products to global partners. Pentapeptide-3 Powder, CAS 725232-44-0, is a diacetate form and a widely used water-soluble peptide raw material in the cosmetics industry. Its molecular sequence is H-Gly-Pro-Arg-Pro-Ala-NH₂. The product is a white powder with excellent water solubility, dissolving directly in aqueous systems without complex pretreatment. This raw material can interact with nicotinic acetylcholine receptors, regulating neuromuscular signal transmission, relieving facial muscle tension, and improving the appearance of dynamic wrinkles caused by repetitive facial movements.
Application of Pentapeptide-3 Powder
Pentapeptide-3 (CAS 725232-44-0), a water-soluble peptide ingredient, is widely used in various facial skincare formulations, suitable for serums, eye care products, and lotions. It is recommended to add it during the later stages of emulsification in production, at a rate of 0.005%-0.01%, with processing temperature controlled below 45℃ and the formulation pH maintained at 5.0-7.0. It can be combined with other peptide components. By regulating neuromuscular signal transmission and relieving muscle tension, it can improve the appearance of wrinkles caused by frequent facial movements. It is intended for use only as a cosmetic ingredient.
COA
| Test Item | Specification | Test Result |
| Appearance | White crystalline powder | Complies |
| Solubility | Freely soluble in water | Complies |
| Purity(HPLC) | ≥98.0% | 98.65% |
| Molecular Weight | 615.68 | Complies |
| Loss on Drying | ≤2.0% | 0.82% |
| Residue on Ignition | ≤0.5% | 0.21% |
| Heavy Metals(Pb) | ≤10ppm | <10ppm |
| Arsenic(As) | ≤2ppm | <2ppm |
| Total Plate Count | ≤100CFU/g | Complies |
| Mold &Yeast | ≤10CFU/g | Complies |
| Escherichia Coli | Negative | Negative |
| Conclusion | Conform with enterprise specification | |
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Pentapeptide-3 (CAS 725232-44-0) is a synthetically produced diacetate pentapeptide. Its sequence is inspired by natural snake venom peptide fragments and, after structural optimization, is adapted for topical skin formulations. Related research focuses on receptor binding characteristics, in vitro cell models, and human skin trials. Molecular docking and in vitro experiments have confirmed that this ingredient can competitively bind to nicotinic acetylcholine receptors, interfering with neuromuscular signal transmission and reducing muscle contraction intensity. In vitro tests show that it can downregulate muscle contraction behavior in a short period of time, and its effects are reversible; muscle condition returns to normal after discontinuation of use.
Mechanism of action of Pentapeptide-3
It targets and binds to nicotinic acetylcholine receptors, competitively occupying receptor sites and weakening neuromuscular signal transmission.
It soothes tense facial muscles, reduces high-frequency muscle contractions, and improves the appearance of skin texture caused by dynamic facial expressions.
Its mechanism of action is to gently regulate signaling pathways without damaging the muscle structure, making it suitable for long-term use in skincare formulations.
When combined with other peptide ingredients, it can create a synergistic effect, further optimizing the skin's appearance.
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With our continuous efforts and good service, we sincerely hope to establish long-term cooperation and common development with customers and give us a chance. We believe that we will satisfy you with first-class quality, safe and fast delivery and enthusiastic after-sales service.
Our Factory
Package
Shipping Methods
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS |
Suitable for under 50kg. International door to door express |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order |
|
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
FAQ
01. What is the amino acid sequence of Pentapeptide-3?
The sequence is H-Gly-Pro-Arg-Pro-Ala-NH₂.
02. What are the appearance and solubility properties of Pentapeptide-3?
It appears as a white powder with good water solubility, dissolving directly in aqueous systems.
03. What are the correct storage conditions?
Pentapeptide-3 Powder needs to be sealed and stored in a dry, dark environment at -20°C, avoiding repeated freeze-thaw cycles.
Click email：Sales4@Faithfulbio.Com Or WhatsApp：+86 17782784907
Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.
Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.
Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.
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